Holzer, Max

Tau and tauopathies

Arendt, T., Stieler, J. T., & Holzer, M. (2016) · Brain Research Bulletin

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 609

Glutaminyl cyclase inhibition attenuates pyroglutamate Aβ and Alzheimer's disease–like pathology

Schilling, S., Zeitschel, U., Hoffmann, T., Heiser, U., Francke, M., Kehlen, A., Holzer, M., Hutter-Paier, B., Prokesch, M., Windisch, M., et al. (2008) · Nature Medicine

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 357

Reversible paired helical filament-like phosphorylation of tau is an adaptive process associated with neuronal plasticity in hibernating animals

Arendt, T., Stieler, J., Strijkstra, A. M., Hut, R. A., Rüdiger, J., Van der Zee, E. A., Harkany, T., Holzer, M., & Härtig, W. (2003) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 357

Expression of the cyclin-dependent kinase inhibitor p16 in Alzheimerʼs disease

Lars Rödel, T. A., Gärtner, U., & Holzer, M. (1996) · NeuroReport

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 250

Tau Oligomers Impair Artificial Membrane Integrity and Cellular Viability

Flach, K., Hilbrich, I., Schiffmann, A., Gärtner, U., Krüger, M., Leonhardt, M., Waschipky, H., Wick, L., Arendt, T., & Holzer, M. (2012) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 188

Expression of endothelial and inducible NOS-isoforms is increased in Alzheimer’s disease, in APP23 transgenic mice and after experimental brain lesion in rat: Evidence for an induction by amyloid pathology

Lüth, H.-J., Holzer, M., Gärtner, U., Staufenbiel, M., & Arendt, T. (2001) · Brain Research

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 183

Neuronal expression of cycline dependent kinase inhibitors of the INK4 family in Alzheimer's disease

Arendt, T., Holzer, M., & Gärtner, U. (1998) · Journal of Neural Transmission

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 137

Aberrant expression of nNOS in pyramidal neurons in Alzheimer's disease is highly co-localized with p21ras and p16INK4a

Lüth, H. J., Holzer, M., Gertz, H.-J., & Arendt, T. (2000) · Brain Research

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 105

Tenascin-R promotes assembly of the extracellular matrix of perineuronal nets via clustering of aggrecan

Morawski, M., Dityatev, A., Hartlage-Rübsamen, M., Blosa, M., Holzer, M., Flach, K., Pavlica, S., Dityateva, G., Grosche, J., Brückner, G., et al. (2014) · Philosophical Transactions of the Royal Society B: Biological Sciences

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 100

Axotrophin/MARCH7 acts as an E3 ubiquitin ligase and ubiquitinates tau protein in vitro impairing microtubule binding

Flach, K., Ramminger, E., Hilbrich, I., Arsalan-Werner, A., Albrecht, F., Herrmann, L., Goedert, M., Arendt, T., & Holzer, M. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Alzheimer's disease research and treatmentsUbiquitin and proteasome pathways

Cited by 58

Progression of neurofibrillary changes and PHF-τ in end-stage Alzheimer’s disease is different from plaque and cortical microglial pathology

Thal, D. R., Arendt, T., Waldmann, G., Holzer, M., Zedlick, D., Rüb, U., & Schober, R. (1998) · Neurobiology of Aging

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 53

The neuronal extracellular matrix restricts distribution and internalization of aggregated Tau-protein

Suttkus, A., Holzer, M., Morawski, M., & Arendt, T. (2016) · Neuroscience

Alzheimer's disease research and treatmentsProteoglycans and glycosaminoglycans research

Cited by 50

Impairment of mitogenic activation of peripheral blood lymphocytes in Alzheimer's disease

Stieler, J. T., Lederer, C., Brückner, M. K., Wolf, H., Holzer, M., Gertz, H.-J., & Arendt, T. (2001) · Neuroreport

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 43