Dolmetsch, Ricardo E.

MicroRNA-mediated conversion of human fibroblasts to neurons

Yoo, A. S., Sun, A. X., Li, L., Shcheglovitov, A., Portmann, T., Li, Y., Lee-Messer, C., Dolmetsch, R. E., Tsien, R. W., & Crabtree, G. R. (2011) · Nature

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 989

p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells

Ihry, R. J., Worringer, K. A., Salick, M. R., Frias, E., Ho, D., Theriault, K., Kommineni, S., Chen, J., Sondey, M., Ye, C., et al. (2018) · Nature Medicine

CRISPR and Genetic EngineeringPluripotent Stem Cells Research

Cited by 978

Signaling to the Nucleus by an L-type Calcium Channel-Calmodulin Complex Through the MAP Kinase Pathway

Dolmetsch, R. E., Pajvani, U., Fife, K., Spotts, J. M., & Greenberg, M. E. (2001) · Science

Ion channel regulation and functionProtein Kinase Regulation and GTPase Signaling

Cited by 900

Gabapentin Receptor α2δ-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis

Eroglu, Ç., Allen, N. J., Susman, M. W., O'Rourke, N. A., Park, C. Y., Özkan, E., Chakraborty, C., Mulinyawe, S. B., Annis, D. S., Huberman, A. D., et al. (2009) · Cell

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 893

Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy

Sun, N., Yazawa, M., Liu, J., Han, L., Sanchez-Freire, V., Abilez, O. J., Navarrete, E. G., Hu, S., Wang, L., Lee, A., et al. (2012) · Science Translational Medicine

Pluripotent Stem Cells ResearchCardiomyopathy and Myosin Studies

Cited by 696

Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome

Yazawa, M., Hsueh, B., Jia, X., Pasca, A. M., Bernstein, J. A., Hallmayer, J., & Dolmetsch, R. E. (2011) · Nature

Cardiac electrophysiology and arrhythmiasPluripotent Stem Cells Research

Cited by 677

Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome

Paşca, S. P., Portmann, T., Voineagu, I., Yazawa, M., Shcheglovitov, A., Paşca, A. M., Cord, B., Palmer, T. D., Chikahisa, S., Nishino, S., et al. (2011) · Nature Medicine

Pluripotent Stem Cells ResearchGenetics and Neurodevelopmental Disorders

Cited by 585

SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients

Shcheglovitov, A., Shcheglovitova, O., Yazawa, M., Portmann, T., Shu, R., Sebastiano, V., Krawisz, A., Froehlich, W., Bernstein, J. A., Hallmayer, J. F., et al. (2013) · Nature

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 470

Behavioral abnormalities and circuit defects in the basal ganglia of a mouse model of 16p11.2 deletion syndrome

Portmann, T., Yang, M., Mao, R., Panagiotakos, G., Ellegood, J., Dolen, G., Bader, P. L., Grueter, B. A., Goold, C., Fisher, E., et al. (2014) · Cell Reports

Genomic variations and chromosomal abnormalitiesGenetics and Neurodevelopmental Disorders

Cited by 245

Neuronal defects in a human cellular model of 22q11.2 deletion syndrome

Khan, T. A., Revah, O., Gordon, A., Yoon, S.-J., Krawisz, A. K., Goold, C., Sun, Y., Kim, C. H., Tian, Y., Li, M.-Y., et al. (2020) · Nature Medicine

Pluripotent Stem Cells ResearchGenomic variations and chromosomal abnormalities

Cited by 186

Molecular mechanisms of autism: a possible role for Ca2+ signaling

Krey, J. F., & Dolmetsch, R. E. (2007) · Current Opinion in Neurobiology

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 169

CLK2 inhibition ameliorates autistic features associated with SHANK3 deficiency

Bidinosti, M., Botta, P., Krüttner, S., Proenca, C. C., Stoehr, N., Bernhard, M., Fruh, I., Mueller, M., Bonenfant, D., Voshol, H., et al. (2016) · Science

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 151

A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients

Sun, Y., Paşca, S. P., Portmann, T., Goold, C., Worringer, K. A., Guan, W., Chan, K. C., Gai, H., Vogt, D., Chen, Y.-J. J., et al. (2016) · eLife

Epilepsy research and treatmentIon channel regulation and function

Cited by 141

16p11.2 deletion syndrome mice display sensory and ultrasonic vocalization deficits during social interactions

Yang, M., Mahrt, E. J., Lewis, F., Foley, G., Portmann, T., Dolmetsch, R. E., Portfors, C. V., & Crawley, J. N. (2015) · Autism Research

Genomic variations and chromosomal abnormalitiesGenetics and Neurodevelopmental Disorders

Cited by 96

Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome

Tian, Y., Voineagu, I., Paşca, S. P., Won, H., Chandran, V., Horvath, S., Dolmetsch, R. E., & Geschwind, D. H. (2014) · Genome Medicine

Genetics and Neurodevelopmental DisordersIon channel regulation and function

Cited by 93

Calcium influx through L-type CaV1.2 Ca2+ channels regulates mandibular development

Ramachandran, K. V., Hennessey, J. A., Barnett, A. S., Yin, X., Stadt, H. A., Foster, E., Shah, R. A., Yazawa, M., Dolmetsch, R. E., Kirby, M. L., et al. (2013) · Journal of Clinical Investigation

Ion channel regulation and functionCraniofacial Disorders and Treatments

Cited by 75

The 22q11.2 region regulates presynaptic gene-products linked to schizophrenia

Nehme, R., Pietiläinen, O., Artomov, M., Tegtmeyer, M., Valakh, V., Lehtonen, L., Bell, C., Singh, T., Trehan, A., Sherwood, J., et al. (2022) · Nature Communications

Genomic variations and chromosomal abnormalitiesSchizophrenia research and treatment

Cited by 58

State-dependent signaling by Cav1.2 regulates hair follicle stem cell function

Yucel, G., Altindag, B., Gomez-Ospina, N., Rana, A., Panagiotakos, G., Lara, M. F., Dolmetsch, R., & Oro, A. E. (2013) · Genes & Development

Hair Growth and DisordersIon channel regulation and function

Cited by 31