Powner, Matthew W.

Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions.

Powner, M. W., Gerland, B., & Sutherland, J. D. (2009) · Nature

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 1,383

Prebiotic synthesis of cysteine peptides that catalyze peptide ligation in neutral water

Foden, C. S., Islam, S., Fernández-García, C., Maugeri, L., Sheppard, T. D., & Powner, M. W. (2020) · Science

Origins and Evolution of LifeChemical Synthesis and Analysis

Cited by 207

Peptide ligation by chemoselective aminonitrile coupling in water

Canavelli, P., Islam, S., & Powner, M. W. (2019) · Nature

Chemical Synthesis and AnalysisOrigins and Evolution of Life

Cited by 188

Prebiotic Systems Chemistry: Complexity Overcoming Clutter

Islam, S., & Powner, M. W. (2017) · Chem

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 154

Chemoselective Multicomponent One-Pot Assembly of Purine Precursors in Water

Powner, M. W., Sutherland, J. D., & Szostak, J. W. (2010) · Journal of the American Chemical Society

Origins and Evolution of LifeMulticomponent Synthesis of Heterocycles

Cited by 150

Prebiotic chemistry: a new modus operandi

Powner, M. W., & Sutherland, J. D. (2011) · Philosophical Transactions of the Royal Society B: Biological Sciences

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 144

Prebiotic selection and assembly of proteinogenic amino acids and natural nucleotides from complex mixtures

Islam, S., Bučar, D.-K., & Powner, M. W. (2017) · Nature Chemistry

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 115

Prebiotic synthesis of phosphoenol pyruvate by α-phosphorylation-controlled triose glycolysis

Coggins, A. J., & Powner, M. W. (2017) · Nature Chemistry

Origins and Evolution of LifePhysical Organic Chemistry and Reaction Kinetics

Cited by 113

Divergent prebiotic synthesis of pyrimidine and 8-oxo-purine ribonucleotides

Stairs, S., Nikmal, A., Bučar, D.-K., Zheng, S.-L., Szostak, J. W., & Powner, M. W. (2017) · Nature Communications

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 113

Prebiotically plausible oligoribonucleotide ligation facilitated by chemoselective acetylation

Bowler, F. R., Chan, C. K. W., Duffy, C. D., Gerland, B., Islam, S., Powner, M. W., Sutherland, J. D., & Xu, J. (2013) · Nature Chemistry

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 108

Functional RNAs exhibit tolerance for non-heritable 2’-5’ versus 3’-5’ backbone heterogeneity

Engelhart, A. E., Powner, M. W., & Szostak, J. W. (2013) · Nature Chemistry

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 107

Heated gas bubbles enrich, crystallize, dry, phosphorylate and encapsulate prebiotic molecules

Morasch, M., Liu, J., Dirscherl, C. F., Ianeselli, A., Kühnlein, A., Le Vay, K., Schwintek, P., Islam, S., Corpinot, M. K., Scheu, B., et al. (2019) · Nature Chemistry

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 96

Direct Assembly of Nucleoside Precursors from Two‐ and Three‐Carbon Units

Anastasi, C., Crowe, M. A., Powner, M. W., & Sutherland, J. D. (2006) · Angewandte Chemie International Edition

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 86

Amino acids catalyse RNA formation under ambient alkaline conditions

Rout, S. K., Wunnava, S., Krepl, M., Cassone, G., Šponer, J. E., Mast, C. B., Powner, M. W., & Braun, D. (2025) · Nature Communications

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 15