Austin, Christopher P.

Organs-on-chips: into the next decade

Low, L. A., Mummery, C., Berridge, B. R., Austin, C. P., & Tagle, D. A. (2021) · Nature Reviews Drug Discovery

3D Printing in Biomedical ResearchTissue Engineering and Regenerative Medicine

Cited by 1,029

The promise and peril of chemical probes

Arrowsmith, C. H., Audia, J. E., Austin, C., Baell, J., Bennett, J., Blagg, J., Bountra, C., Brennan, P. E., Brown, P. J., Bunnage, M. E., et al. (2015) · Nature Chemical Biology

Click Chemistry and ApplicationsComputational Drug Discovery Methods

Cited by 839

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

Anastasiou, D., Yu, Y., Israelsen, W. J., Jiang, J.-K., Boxer, M. B., Hong, B. S., Tempel, W., Dimov, S., Shen, M., Jha, A., et al. (2012) · Nature Chemical Biology

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 816

The National COVID Cohort Collaborative (N3C): Rationale, design, infrastructure, and deployment

Haendel, M. A., Chute, C. G., Bennett, T. D., Eichmann, D. A., Guinney, J., Kibbe, W. A., Payne, P. R. O., Pfaff, E. R., Robinson, P. N., Saltz, J. H., et al. (2021) · Journal of the American Medical Informatics Association

Research Data Management PracticesElectronic Health Records Systems

Cited by 553

Therapies for rare diseases: therapeutic modalities, progress and challenges ahead

Tambuyzer, E., Vandendriessche, B., Austin, C. P., Brooks, P. J., Larsson, K., Miller Needleman, K. I., Valentine, J., Davies, K., Groft, S. C., Preti, R., et al. (2020) · Nature Reviews Drug Discovery

Pharmaceutical Economics and PolicyGenomics and Rare Diseases

Cited by 357

The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology

Richard, A. M., Huang, R., Waidyanatha, S., Shinn, P., Collins, B. J., Thillainadarajah, I., Grulke, C. M., Williams, A. J., Lougee, R. R., Judson, R. S., et al. (2021) · Chemical Research in Toxicology

Computational Drug Discovery MethodsEnvironmental Toxicology and Ecotoxicology

Cited by 323

The Tox21 robotic platform for the assessment of environmental chemicals – from vision to reality

Attene-Ramos, M. S., Miller, N., Huang, R., Michael, S., Itkin, M., Kavlock, R. J., Austin, C. P., Shinn, P., Simeonov, A., Tice, R. R., et al. (2013) · Drug Discovery Today

Effects and risks of endocrine disrupting chemicalsComputational Drug Discovery Methods

Cited by 255

Opportunities and challenges in translational science

Austin, C. P. (2021) · Clinical and Translational Science

Health and Medical Research ImpactsInterdisciplinary Research and Collaboration

Cited by 188

Glimmers in illuminating the druggable genome

Rodgers, G., Austin, C., Anderson, J., Pawlyk, A., Colvis, C., Margolis, R., & Baker, J. (2018) · Nature Reviews Drug Discovery

Computational Drug Discovery MethodsScience, Research, and Medicine

Cited by 126

Collaborative Development of 2-Hydroxypropyl-β-Cyclodextrin for the Treatment of Niemann-Pick Type C1 Disease

Ottinger, E., Kao, M., Carrillo-Carrasco, N., Yanjanin, N., Shankar, R., Janssen, M., Brewster, M., Scott, I., Xu, X., Cradock, J., et al. (2014) · Current Topics in Medicinal Chemistry

Lysosomal Storage Disorders ResearchGlycogen Storage Diseases and Myoclonus

Cited by 121

Advancing translational science education

Faupel‐Badger, J. M., Vogel, A. L., Austin, C. P., & Rutter, J. L. (2022) · Clinical and Translational Science

Health and Medical Research ImpactsInnovations in Medical Education

Cited by 85

Application of a Dynamic Map for Learning, Communicating, Navigating, and Improving Therapeutic Development

Wagner, J. A., Dahlem, A. M., Hudson, L. D., Terry, S. F., Altman, R. B., Gilliland, C. T., DeFeo, C., & Austin, C. P. (2018) · Clinical and Translational Science

Health and Medical Research ImpactsInterdisciplinary Research and Collaboration

Cited by 45

Recommendations toward a human pathway-based approach to disease research

Marshall, L. J., Austin, C. P., Casey, W., Fitzpatrick, S. C., & Willett, C. (2018) · Drug Discovery Today

Animal testing and alternativesComputational Drug Discovery Methods

Cited by 28

Evaluation of Cholesterol Reduction Activity of Methyl-β-cyclodextrin Using Differentiated Human Neurons and Astrocytes

Swaroop, M., Thorne, N., Rao, M. S., Austin, C. P., McKew, J. C., & Zheng, W. (2012) · SLAS Discovery

Lysosomal Storage Disorders ResearchCholesterol and Lipid Metabolism

Cited by 22