Lassen, Kara G.

Advances in inflammatory bowel disease pathogenesis: linking host genetics and the microbiome

Knights, D., Lassen, K. G., & Xavier, R. J. (2013) · Gut

Inflammatory Bowel DiseaseGut microbiota and health

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Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense

Lassen, K. G., Kuballa, P., Conway, K. L., Patel, K. K., Becker, C. E., Peloquin, J. M., Villablanca, E. J., Norman, J. M., Liu, T.-C., Heath, R. J., et al. (2014) · Proceedings of the National Academy of Sciences

Autophagy in Disease and TherapyInflammatory Bowel Disease

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RNF166 determines recruitment of adaptor proteins during antibacterial autophagy

Heath, R. J., Goel, G., Baxt, L. A., Rush, J. S., Mohanan, V., Paulus, G. L. C., Jani, V., Lassen, K. G., & Xavier, R. J. (2016) · Cell Reports

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

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Short-term dietary changes can result in mucosal and systemic immune depression

Siracusa, F., Schaltenberg, N., Kumar, Y., Lesker, T. R., Steglich, B., Liwinski, T., Cortesi, F., Frommann, L., Diercks, B.-P., Bönisch, F., et al. (2023) · Nature Immunology

Gut microbiota and healthT-cell and B-cell Immunology

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TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41

Carey, K. L., Paulus, G. L. C., Wang, L., Balce, D. R., Luo, J. W., Bergman, P., Ferder, I. C., Kong, L., Renaud, N., Singh, S., et al. (2020) · Cell Reports

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

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