Pothula, Santosh

GABA interneurons are the cellular trigger for ketamine's rapid antidepressant actions

Gerhard, D. M., Pothula, S., Liu, R.-J., Wu, M., Li, X.-Y., Girgenti, M. J., Taylor, S. R., Duman, C. H., Delpire, E., Picciotto, M., et al. (2020) · Journal of Clinical Investigation

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 345

Optogenetic stimulation of medial prefrontal cortex Drd1 neurons produces rapid and long-lasting antidepressant effects

Hare, B. D., Shinohara, R., Liu, R. J., Pothula, S., DiLeone, R. J., & Duman, R. S. (2019) · Nature Communications

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 217

Ketamine disinhibits dendrites and enhances calcium signals in prefrontal dendritic spines

Ali, F., Gerhard, D. M., Sweasy, K., Pothula, S., Pittenger, C., Duman, R. S., & Kwan, A. C. (2020) · Nature Communications

Neuroscience and Neuropharmacology ResearchTreatment of Major Depression

Cited by 196

Sestrin modulator NV-5138 produces rapid antidepressant effects via direct mTORC1 activation

Kato, T., Pothula, S., Liu, R.-J., Duman, C. H., Terwilliger, R., Vlasuk, G. P., Saiah, E., Hahm, S., & Duman, R. S. (2019) · Journal of Clinical Investigation

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 88