Bendall, Sean C.

Data-Driven Phenotypic Dissection of AML Reveals Progenitor-like Cells that Correlate with Prognosis

Levine, J. H., Simonds, E. F., Bendall, S. C., Davis, K. L., Amir, E.-A. D., Tadmor, M. D., Litvin, O., Fienberg, H. G., Jager, A., Zunder, E. R., et al. (2015) · Cell

Acute Myeloid Leukemia ResearchSingle-cell and spatial transcriptomics

Cited by 2,303

Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum

Bendall, S. C., Simonds, E. F., Qiu, P., Amir, E.-A. D., Krutzik, P. O., Finck, R., Bruggner, R. V., Melamed, R., Trejo, A., Ornatsky, O. I., et al. (2011) · Science

Single-cell and spatial transcriptomicsMetabolomics and Mass Spectrometry Studies

Cited by 2,279

viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia

Amir, E.-A. D., Davis, K. L., Tadmor, M. D., Simonds, E. F., Levine, J. H., Bendall, S. C., Shenfeld, D. K., Krishnaswamy, S., Nolan, G. P., & Pe'er, D. (2013) · Nature Biotechnology

Single-cell and spatial transcriptomicsData Visualization and Analytics

Cited by 1,550

A Structured Tumor-Immune Microenvironment in Triple Negative Breast Cancer Revealed by Multiplexed Ion Beam Imaging

Keren, L., Bosse, M., Marquez, D., Angoshtari, R., Jain, S., Varma, S., Yang, S.-R., Kurian, A., Van Valen, D., West, R., et al. (2018) · Cell

Cancer Immunotherapy and BiomarkersSingle-cell and spatial transcriptomics

Cited by 1,183

Multiplexed ion beam imaging of human breast tumors

Angelo, M., Bendall, S. C., Finck, R., Hale, M. B., Hitzman, C., Borowsky, A. D., Levenson, R. M., Lowe, J. B., Liu, S. D., Zhao, S., et al. (2014) · Nature Medicine

Mass Spectrometry Techniques and ApplicationsIon-surface interactions and analysis

Cited by 1,108

Systemic Immunity Is Required for Effective Cancer Immunotherapy

Spitzer, M. H., Carmi, Y., Reticker-Flynn, N. E., Kwek, S. S., Madhireddy, D., Martins, M. M., Gherardini, P. F., Prestwood, T. R., Chabon, J., Bendall, S. C., et al. (2017) · Cell

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 963

Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE

Qiu, P., Simonds, E. F., Bendall, S. C., Gibbs, K. D., Bruggner, R. V., Linderman, M. D., Sachs, K., Nolan, G. P., & Plevritis, S. K. (2011) · Nature Biotechnology

Single-cell and spatial transcriptomicsCell Image Analysis Techniques

Cited by 956

Whole-cell segmentation of tissue images with human-level performance using large-scale data annotation and deep learning

Greenwald, N. F., Miller, G., Moen, E., Kong, A., Kagel, A., Dougherty, T., Fullaway, C. C., McIntosh, B. J., Leow, K. X., Schwartz, M. S., et al. (2022) · Nature Biotechnology

Cell Image Analysis TechniquesAI in cancer detection

Cited by 953

Single-Cell Trajectory Detection Uncovers Progression and Regulatory Coordination in Human B Cell Development

Bendall, S. C., Davis, K. L., Amir, E.-A. D., Tadmor, M. D., Simonds, E. F., Chen, T. J., Shenfeld, D. K., Nolan, G. P., & Pe’er, D. (2014) · Cell

Single-cell and spatial transcriptomicsT-cell and B-cell Immunology

Cited by 906

Wishbone identifies bifurcating developmental trajectories from single-cell data

Setty, M., Tadmor, M. D., Reich-Zeliger, S., Angel, O., Salame, T. M., Kathail, P., Choi, K., Bendall, S., Friedman, N., & Pe'er, D. (2016) · Nature Biotechnology

Single-cell and spatial transcriptomicsGene Regulatory Network Analysis

Cited by 558

Cytometry by time-of-flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8+ T cell phenotypes

Newell, E. W., Sigal, N., Bendall, S. C., Nolan, G. P., & Davis, M. M. (2012) · Immunity

T-cell and B-cell ImmunologyImmune Cell Function and Interaction

Cited by 555

Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators

Bodenmiller, B., Zunder, E. R., Finck, R., Chen, T. J., Savig, E. S., Bruggner, R. V., Simonds, E. F., Bendall, S. C., Sachs, K., Krutzik, P. O., et al. (2012) · Nature Biotechnology

Metabolomics and Mass Spectrometry StudiesAdvanced Proteomics Techniques and Applications

Cited by 546

Conditional density-based analysis of T cell signaling in single-cell data

Krishnaswamy, S., Spitzer, M. H., Mingueneau, M., Bendall, S. C., Litvin, O., Stone, E., Pe’er, D., & Nolan, G. P. (2014) · Science

Gene Regulatory Network AnalysisSingle-cell and spatial transcriptomics

Cited by 225

Glucose Metabolism Drives Histone Acetylation Landscape Transitions that Dictate Muscle Stem Cell Function

Yucel, N., Wang, Y. X., Mai, T., Porpiglia, E., Lund, P. J., Markov, G., Garcia, B. A., Bendall, S. C., Angelo, M., & Blau, H. M. (2019) · Cell Reports

Muscle Physiology and DisordersMetabolism, Diabetes, and Cancer

Cited by 159

High-resolution myogenic lineage mapping by single-cell mass cytometry

Porpiglia, E., Samusik, N., Ho, A. T. V., Cosgrove, B. D., Mai, T., Davis, K. L., Jager, A., Nolan, G. P., Bendall, S. C., Fantl, W. J., et al. (2017) · Nature Cell Biology

Muscle Physiology and DisordersCongenital heart defects research

Cited by 128

Comprehensive Immune Monitoring of Clinical Trials to Advance Human Immunotherapy

Hartmann, F. J., Babdor, J., Gherardini, P. F., Amir, E.-A. D., Jones, K., Sahaf, B., Marquez, D. M., Krutzik, P., O’Donnell, E., Sigal, N., et al. (2019) · Cell Reports

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 124

Single-Cell Mass Cytometry Analysis of Human Tonsil T Cell Remodeling by Varicella Zoster Virus

Sen, N., Mukherjee, G., Sen, A., Bendall, S. C., Sung, P., Nolan, G. P., & Arvin, A. M. (2014) · Cell Reports

Herpesvirus Infections and TreatmentsT-cell and B-cell Immunology

Cited by 90