Inoue, Akira

Identification of small molecule proliferating cell nuclear antigen (PCNA) inhibitor that disrupts interactions with PIP-box proteins and inhibits DNA replication

Punchihewa, C., Inoue, A., Hishiki, A., Fujikawa, Y., Connelly, M., Evison, B., Shao, Y., Heath, R., Kuraoka, I., Rodrigues, P., et al. (2012) · Journal of Biological Chemistry

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 135

Senescence and cytoskeleton: overproduction of vimentin induces senescent-like morphology in human fibroblasts

Nishio, K., Inoue, A., Qiao, S., Kondo, H., & Mimura, A. (2001) · Histochemistry and Cell Biology

Telomeres, Telomerase, and SenescenceSkin and Cellular Biology Research

Cited by 115

Phospho-Ser727 of STAT3 regulates STAT3 activity by enhancing dephosphorylation of phospho-Tyr705 largely through TC45

Wakahara, R., Kunimoto, H., Tanino, K., Kojima, H., Inoue, A., Shintaku, H., & Nakajima, K. (2012) · Genes to Cells

Cytokine Signaling Pathways and InteractionsProtein Tyrosine Phosphatases

Cited by 95

Identification of the first small-molecule inhibitor of the REV7 DNA repair protein interaction

Actis, M. L., Ambaye, N. D., Evison, B. J., Shao, Y., Vanarotti, M., Inoue, A., McDonald, E. T., Kikuchi, S., Heath, R., Hara, K., et al. (2016) · Bioorganic & Medicinal Chemistry

DNA Repair MechanismsMetal complexes synthesis and properties

Cited by 42

Small-molecules that bind to the ubiquitin-binding motif of REV1 inhibit REV1 interaction with K164-monoubiquitinated PCNA and suppress DNA damage tolerance

Vanarotti, M., Evison, B. J., Actis, M. L., Inoue, A., McDonald, E. T., Shao, Y., Heath, R. J., & Fujii, N. (2018) · Bioorganic & Medicinal Chemistry

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 17