Identification of the first small-molecule inhibitor of the REV7 DNA repair protein interaction

DNA interstrand crosslink repair and cancer

Deans, A. J., & West, S. C. (2011) · Nature reviews. Cancer · doi:10.1038/nrc3088 · Cited by 1,019 · see citing works

REV7 counteracts DNA double-strand break resection and affects PARP inhibition

Xu, G., Chapman, J. R., Brandsma, I., Yuan, J., Mistrík, M., Bouwman, P., Bártková, J., Gogola, E., Warmerdam, D. O., Barazas, M., et al. (2015) · Nature · doi:10.1038/nature14328 · Cited by 594 · see citing works

WaterLOGSY as a method for primary NMR screening: Practical aspects and range of applicability

Dalvit, C., Fogliatto, G., Stewart, A., Veronesi, M., & Stockman, B. J. (2001) · Journal of Biomolecular NMR · doi:10.1023/a:1013302231549 · Cited by 570 · see citing works

Mechanism of Replication-Coupled DNA Interstrand Crosslink Repair

Räschle, M., Knipscheer, P., Enoiu, M., Angelov, T., Sun, J., Griffith, J. D., Ellenberger, T., Schärer, O. D., & Walter, J. C. (2008) · Cell · doi:10.1016/j.cell.2008.08.030 · Cited by 507 · see citing works

Enhancing tumor cell response to chemotherapy through nanoparticle-mediated codelivery of siRNA and cisplatin prodrug

Xu, X., Xie, K., Zhang, X.-Q., Pridgen, E. M., Park, G. Y., Cui, D. S., Shi, J., Wu, J., Kantoff, P. W., Lippard, S. J., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1303958110 · Cited by 340 · see citing works

MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5′ end resection

Boersma, V., Moatti, N., Segura‐Bayona, S., Peuscher, M. H., van der Torre, J., Wevers, B. A., Orthwein, A., Durocher, D., & Jacobs, J. J. L. (2015) · Nature · doi:10.1038/nature14216 · Cited by 304 · see citing works

Advances in Understanding the Complex Mechanisms of DNA Interstrand Cross-Link RepairPreprint

Clauson, C. L., Schärer, O. D., & Niedernhofer, L. J. (2013) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a012732 · Cited by 245 · see citing works

DNA polymerase zeta (pol ζ) in higher eukaryotes

Gan, G. N., Wittschieben, J. P., Wittschieben, B. Ø., & Wood, R. D. (2007) · Cell Research · doi:10.1038/cr.2007.117 · Cited by 202 · see citing works

Suppression of Rev3, the catalytic subunit of Polζ, sensitizes drug-resistant lung tumors to chemotherapy

Doles, J., Oliver, T. G., Cameron, E. R., Hsu, G., Jacks, T., Walker, G. C., & Hemann, M. T. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1011409107 · Cited by 190 · see citing works

A Human REV7 Homolog That Interacts with the Polymerase ζ Catalytic Subunit hREV3 and the Spindle Assembly Checkpoint Protein hMAD2

Murakumo, Y., Roth, T., Ishii, H., Rasio, D., Numata, S., Croce, C. M., & Fishel, R. A. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.6.4391 · Cited by 181 · see citing works

Human Pol ζ purified with accessory subunits is active in translesion DNA synthesis and complements Pol η in cisplatin bypass

Lee, Y., Gregory, M., & Yang, W. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1324001111 · Cited by 167 · see citing works

MAD2B is an inhibitor of the anaphase-promoting complexPreprint

Chen, J., & Fang, G. (2001) · Genes & Development · doi:10.1101/gad.898701 · Cited by 144 · see citing works

Inhibition of Cdh1–APC by the MAD2-related protein MAD2L2: a novel mechanism for regulating Cdh1Preprint

Pfleger, C. M., Salic, A. N., Lee, E. N., & Kirschner, M. W. (2001) · Genes & Development · doi:10.1101/gad.897901 · Cited by 140 · see citing works

Cellular Functions of DNA Polymerase ζ and Rev1 Protein

Lawrence, C. W. (2004) · Advances in protein chemistry · doi:10.1016/s0065-3233(04)69006-1 · Cited by 137 · see citing works

Differential Roles for DNA Polymerases Eta, Zeta, and REV1 in Lesion Bypass of Intrastrand versus Interstrand DNA Cross-Links

Hicks, J. K., Chute, C. L., Paulsen, M. T., Ragland, R. L., Howlett, N. G., Guéranger, Q., Glover, T. W., & Canman, C. E. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.00993-09 · Cited by 129 · see citing works

Translesion DNA synthesis polymerases in DNA interstrand crosslink repair

Ho, T. V., & Schärer, O. D. (2010) · Environmental and Molecular Mutagenesis · doi:10.1002/em.20573 · Cited by 126 · see citing works

Crystal Structure of Human REV7 in Complex with a Human REV3 Fragment and Structural Implication of the Interaction between DNA Polymerase ζ and REV1

Hara, K., Hashimoto, H., Murakumo, Y., Kobayashi, S., Kogame, T., Unzai, S., Akashi, S., Takeda, S., Shimizu, T., & Sato, M. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.092403 · Cited by 123 · see citing works

Structural Basis of Rev1-mediated Assembly of a Quaternary Vertebrate Translesion Polymerase Complex Consisting of Rev1, Heterodimeric Polymerase (Pol) ζ, and Pol κ

Wojtaszek, J. L., Lee, C., D’Souza, S., Minesinger, B. K., Kim, H., D’Andrea, A. D., Walker, G. C., & Zhou, P. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.394841 · Cited by 111 · see citing works

DNA Polymerase ζ Regulates Cisplatin Cytotoxicity, Mutagenicity, and The Rate of Development of Cisplatin Resistance

Wu, F., Lin, X., Okuda, T., & Howell, S. B. (2004) · Cancer Research · doi:10.1158/0008-5472.can-03-3942 · Cited by 110 · see citing works

Structural Basis of Recruitment of DNA Polymerase ζ by Interaction between REV1 and REV7 Proteins

Kikuchi, S., Hara, K., Shimizu, T., Sato, M., & Hashimoto, H. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.396838 · Cited by 103 · see citing works

A Small Molecule Inhibitor of Monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) Inhibits Repair of Interstrand DNA Cross-link, Enhances DNA Double Strand Break, and Sensitizes Cancer Cells to Cisplatin

Inoue, A., Kikuchi, S., Hishiki, A., Shao, Y., Heath, R. J., Evison, B. J., Actis, M. L., Canman, C. E., Hashimoto, H., & Fujii, N. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.520429 · Cited by 99 · see citing works

REV3 and REV1 Play Major Roles in Recombination-independent Repair of DNA Interstrand Cross-links Mediated by Monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA)

Shen, X. H., Jun, S., O'Neal, L. E., Sonoda, E., Bemark, M., Sale, J. E., & Li, L. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.c600071200 · Cited by 97 · see citing works

Inactivation of Human MAD2B in Nasopharyngeal Carcinoma Cells Leads to Chemosensitization to DNA-Damaging Agents

Cheung, H. W., Chun, A. C. S., Wang, Q., Deng, W., Hu, L., Guan, X., Nicholls, J. M., Ling, M., Wong, Y. C., Tsao, S. W., et al. (2006) · Cancer Research · doi:10.1158/0008-5472.can-05-3602 · Cited by 91 · see citing works

Overcoming the solubility limit with solubility-enhancement tags: successful applications in biomolecular NMR studies

Zhou, P., & Wagner, G. H. (2009) · Journal of Biomolecular NMR · doi:10.1007/s10858-009-9371-6 · Cited by 84 · see citing works

REV7 is essential for DNA damage tolerance via two REV3L binding sites in mammalian DNA polymerase ζ

Tomida, J., Takata, K., Lange, S. S., Schibler, A. C., Yousefzadeh, M. J., Bhetawal, S., Dent, S., & Wood, R. D. (2015) · Nucleic Acids Research · doi:10.1093/nar/gku1385 · Cited by 64 · see citing works

Suppression of REV 7 enhances cisplatin sensitivity in ovarian clear cell carcinoma cells

Niimi, K., Murakumo, Y., Watanabe, N., Kato, T., Mii, S., Enomoto, A., Asai, M., Asai, N., Yamamoto, E., Kajiyama, H., et al. (2014) · Cancer Science · doi:10.1111/cas.12390 · Cited by 56 · see citing works

REV1 and DNA polymerase zeta in DNA interstrand crosslink repair

Sharma, S., & Canman, C. E. (2012) · Environmental and Molecular Mutagenesis · doi:10.1002/em.21736 · Cited by 54 · see citing works

Sequence requirement and subtype specificity in the high‐affinity interaction between human frizzled and dishevelled proteins

Punchihewa, C., Ferreira, A. M., Cassell, R. J., Rodrigues, P., & Fujii, N. (2009) · Protein Science · doi:10.1002/pro.109 · Cited by 50 · see citing works

Rev7/MAD2B Links c-Jun N-Terminal Protein Kinase Pathway Signaling to Activation of the Transcription Factor Elk-1

Zhang, L., Yang, S., & Sharrocks, A. D. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.02276-06 · Cited by 47 · see citing works

The Vital Role of Polymerase ζ and REV1 in Mutagenic, but Not Correct, DNA Synthesis across Benzo[a]pyrene-dG and Recruitment of Polymerase ζ by REV1 to Replication-stalled Site

Hashimoto, K., Cho, Y., Yang, I.-Y., Akagi, J., Ohashi, E., Tateishi, S., de Wind, N., Hanaoka, F., Ohmori, H., & Moriya, M. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.331728 · Cited by 45 · see citing works

The Transcription Factor TFII-I Promotes DNA Translesion Synthesis and Genomic Stability

Fattah, F. J., Hara, K., Fattah, K. R., Yang, C., Wu, N., Warrington, R. T., Chen, D. J., Zhou, P., Boothman, D. A., & Yu, H. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004419 · Cited by 44 · see citing works

The property of DNA polymerase ζ: REV7 is a putative protein involved in translesion DNA synthesis and cell cycle control

Murakumo, Y. (2002) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/s0027-5107(02)00250-6 · Cited by 38 · see citing works

Rev7/Mad2B plays a critical role in the assembly of a functional mitotic spindle

Bhat, A., Wu, Z., Maher, V. M., McCormick, J. J., & Xiao, W. (2015) · Cell Cycle · doi:10.1080/15384101.2015.1120922 · Cited by 36 · see citing works

Overlapping in short motif sequences for binding to human REV7 and MAD2 proteins

Hanafusa, T., Habu, T., Tomida, J., Ohashi, E., Murakumo, Y., & Ohmori, H. (2010) · Genes to Cells · doi:10.1111/j.1365-2443.2009.01380.x · Cited by 32 · see citing works

Purification, crystallization and initial X-ray diffraction study of human REV7 in complex with a REV3 fragment

Hara, K., Shimizu, T., Unzai, S., Akashi, S., Sato, M., & Hashimoto, H. (2009) · Acta Crystallographica Section F Structural Biology and Crystallization Communications · doi:10.1107/s1744309109046181 · Cited by 28 · see citing works

A Missense Mutation in Rev7 Disrupts Formation of Polζ, Impairing Mouse Development and Repair of Genotoxic Agent-induced DNA Lesions

Khalaj, M., Abbasi, A., Yamanishi, H., Akiyama, K., Wakitani, S., Kikuchi, S., Hirose, M., Yuzuriha, M., Magari, M., Degheidy, H. A., et al. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.514752 · Cited by 28 · see citing works

REV7/MAD2L2: the multitasking maestro emerges as a barrier to recombination

Sale, J. E. (2015) · The EMBO Journal · doi:10.15252/embj.201591697 · Cited by 22 · see citing works

Destabilization of pluripotency in the absence of Mad2l2

Pirouz, M., Rahjouei, A., Shamsi, F., Eckermann, K. N., Salinas, G., Pommerenke, C., & Kessel, M. (2015) · Cell Cycle · doi:10.1080/15384101.2015.1026485 · Cited by 19 · see citing works

A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy

Wojtaszek, J. L., Chatterjee, N., Najeeb, J., Ramos, A., Lee, M., Bian, K., Xue, J. Y., Fenton, B. A., Park, H., Li, D., et al. (2019) · Cell · doi:10.1016/j.cell.2019.05.028 · Cited by 194 · see citing works

CDK-Independent and PCNA-Dependent Functions of p21 in DNA Replication

Mansilla, S. F., De La Vega, M. B., Calzetta, N. L., Siri, S. O., & Gottifredi, V. (2020) · Genes · doi:10.3390/genes11060593 · Cited by 114 · see citing works

Inhibition of mutagenic translesion synthesis: A possible strategy for improving chemotherapy?

Yamanaka, K., Chatterjee, N., Hemann, M. T., & Walker, G. C. (2017) · PLOS Genetics · doi:10.1371/journal.pgen.1006842 · Cited by 87 · see citing works

Targeting DNA repair and replication stress in the treatment of ovarian cancer

Murai, J. (2017) · International Journal of Clinical Oncology · doi:10.1007/s10147-017-1145-7 · Cited by 75 · see citing works

Roles of trans-lesion synthesis (TLS) DNA polymerases in tumorigenesis and cancer therapy

Anand, J. R., Chiou, L. F., Sciandra, C. A., Zhang, X., Hong, J., Wu, D., Zhou, P., & Vaziri, C. (2023) · NAR Cancer · doi:10.1093/narcan/zcad005 · Cited by 73 · see citing works

Fanconi anemia pathway as a prospective target for cancer intervention

Liu, W., Palovcak, A., Li, F., Zafar, A., Yuan, F., & Zhang, Y. (2020) · Cell & Bioscience · doi:10.1186/s13578-020-00401-7 · Cited by 67 · see citing works

Structure and mechanism of B-family DNA polymerase ζ specialized for translesion DNA synthesis

Malik, R., Kopylov, M., Gómez-Llorente, Y., Jain, R., Johnson, R. E., Prakash, L., Prakash, S., Ubarretxena‐Belandia, I., & Aggarwal, A. K. (2020) · Nature Structural & Molecular Biology · doi:10.1038/s41594-020-0476-7 · Cited by 67 · see citing works

REV7: Jack of many trades

de Krijger, I., Boersma, V., & Jacobs, J. (2021) · Trends in Cell Biology · doi:10.1016/j.tcb.2021.04.002 · Cited by 40 · see citing works

Mitotic syndicates Aurora Kinase B (AURKB) and mitotic arrest deficient 2 like 2 (MAD2L2) in cohorts of DNA damage response (DDR) and tumorigenesis

Marima, R. M., Hull, R., Penny, C. B., & Dlamini, Z. (2021) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2021.108376 · Cited by 55 · see citing works

Translesion DNA Synthesis in Cancer: Molecular Mechanisms and Therapeutic Opportunities

Zafar, M. K., & Eoff, R. L. (2017) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.7b00157 · Cited by 47 · see citing works

Beyond Kinases: Targeting Replication Stress Proteins in Cancer Therapy

Baillie, K. E., & Stirling, P. C. (2020) · Trends in cancer · doi:10.1016/j.trecan.2020.10.010 · Cited by 40 · see citing works

Translesion synthesis inhibitors as a new class of cancer chemotherapeutics

Patel, S. M., Dash, R. C., & Hadden, M. K. (2020) · Expert Opinion on Investigational Drugs · doi:10.1080/13543784.2021.1850692 · Cited by 39 · see citing works

Targeting protein–protein interactions in the DNA damage response pathways for cancer chemotherapy

McPherson, K. S., & Korzhnev, D. M. (2021) · RSC Chemical Biology · doi:10.1039/d1cb00101a · Cited by 33 · see citing works

Inactivation of REV7 enhances chemosensitivity and overcomes acquired chemoresistance in testicular germ cell tumors

Sakurai, Y., Ichinoe, M., Yoshida, K., Nakazato, Y., Saito, S., Satoh, M., Nakada, N., Sanoyama, I., Umezawa, A., Numata, Y., et al. (2020) · Cancer Letters · doi:10.1016/j.canlet.2020.06.001 · Cited by 30 · see citing works

Replication Fork Remodeling and Therapy Escape in DNA Damage Response-Deficient Cancers

Liptay, M., Barbosa, J. S., & Rottenberg, S. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.00670 · Cited by 29 · see citing works

Post-replication repair: Rad5/HLTF regulation, activity on undamaged templates, and relationship to cancer

Gallo, D., & Brown, G. W. (2019) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409238.2019.1651817 · Cited by 21 · see citing works

Inhibition of Human DNA Polymerases Eta and Kappa by Indole-Derived Molecules Occurs through Distinct Mechanisms

Ketkar, A. D., Maddukuri, L., Penthala, N. R., Reed, M. R., Zafar, M. K., Crooks, P. A., & Eoff, R. L. (2019) · ACS Chemical Biology · doi:10.1021/acschembio.9b00304 · Cited by 21 · see citing works

Translesion DNA Synthesis and Reinitiation of DNA Synthesis in Chemotherapy Resistance

Shilkin, E. S., Boldinova, E. O., Stolyarenko, A. D., Гончарова, Р. И., Chuprov‐Netochin, R. N., Smal, M. P., & Makarova, А. V. (2020) · Biochemistry (Moscow) · doi:10.1134/s0006297920080039 · Cited by 18 · see citing works

Small-molecules that bind to the ubiquitin-binding motif of REV1 inhibit REV1 interaction with K164-monoubiquitinated PCNA and suppress DNA damage tolerance

Vanarotti, M., Evison, B. J., Actis, M. L., Inoue, A., McDonald, E. T., Shao, Y., Heath, R. J., & Fujii, N. (2018) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2018.03.028 · Cited by 17 · see citing works

N-(4-acetamidophenyl)-5-acetylfuran-2-carboxamide as a novel orally available diuretic that targets urea transporters with improved PD and PK properties

Wang, S., Xu, Y. C., Zhao, Y. T., Zhang, S., Li, M., Li, X., He, J., Zhou, H., Ge, Z., Li, R., et al. (2021) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2021.113859 · Cited by 17 · see citing works

REV7 in Cancer Biology and Management

Murakumo, Y., Sakurai, Y., Kato, T., Hashimoto, H., & Ichinoe, M. (2023) · Cancers · doi:10.3390/cancers15061721 · Cited by 14 · see citing works

Protein–Protein Interactions in Translesion Synthesis

Dash, R. C., & Hadden, M. K. (2021) · Molecules · doi:10.3390/molecules26185544 · Cited by 12 · see citing works

Structural insight into inhibition of REV7 protein interaction revealed by docking, molecular dynamics and MM/PBSA studies

Ren, X., Zeng, R., Wang, C., Zhang, M., Liang, C., Tang, Z., & Ren, J. (2017) · RSC Advances · doi:10.1039/c7ra03716c · Cited by 11 · see citing works

One-Step Synthesis of Thieno[2,3-d]pyrimidin-4(3H)-ones via a Catalytic Four-Component Reaction of Ketones, Ethyl Cyanoacetate, S8, and Formamide

Shi, T., Kaneko, L. K., Sandino, M., Busse, R., Zhang, M., Mason, D. J., Machulis, J., Ambrose, A. J., Zhang, D. D., & Chapman, E. (2018) · ACS Sustainable Chemistry & Engineering · doi:10.1021/acssuschemeng.8b05276 · Cited by 11 · see citing works

REV7 is involved in outcomes of platinum‐based chemotherapy in pancreatic cancer by controlling the DNA damage response

Tamaki, A., Kato, T., Sakurai, Y., Sato, K., Adachi, K., Tadehara, M., Kogami, T., Matsushita, M., Hoshino, A., Sanoyama, I., et al. (2023) · Cancer Science · doi:10.1111/cas.16044 · Cited by 10 · see citing works

Protein Assemblies in Translesion Synthesis

Arianna, G. A., & Korzhnev, D. M. (2024) · Genes · doi:10.3390/genes15070832 · Cited by 10 · see citing works

Design, synthesis, and evaluation of the self‐assembled antimicrobial peptides based on the ovalbumin‐derived peptide TK913

Tan, A., Xu, F., Yokoyama, C., Yano, S., & Konno, H. (2021) · Journal of Peptide Science · doi:10.1002/psc.3375 · Cited by 9 · see citing works

Inhibitors of the Fanconi anaemia pathway as potential antitumour agents for ovarian cancer

Taylor, S. J., Arends, M. J., & Langdon, S. P. (2020) · Exploration of Targeted Anti-tumor Therapy · doi:10.37349/etat.2020.00003 · Cited by 8 · see citing works

SLFN11 counteracts the RFWD3-PRIMPOL DNA damage tolerance axis to restrain gapped DNA synthesis in response to replication stress

Coleman, K. E., Shin, D.-W., Goehring, L. J., Szeitz, B., Fenyö, D., Rothenberg, E., Poirier, J. T., & Huang, T. T. (2025) · Nature Communications · doi:10.1038/s41467-025-66068-1 · Cited by 6 · see citing works

Potential Strategies to Target Protein–Protein Interactions in the DNA Damage Response and Repair Pathways

Fujii, N. (2017) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.7b00358 · Cited by 6 · see citing works

Antiviral peptides inhibiting the main protease of SARS‐CoV‐2 investigated by computational screening and in vitro protease assay

Stewart, J. T., Shawon, J., Ali, M., Williams, B., Shahinuzzaman, A. D. A., Rupa, S. A., Al‐Adhami, T., Jia, R., Bourque, C., Faddis, R., et al. (2023) · Journal of Peptide Science · doi:10.1002/psc.3553 · Cited by 4 · see citing works

Peptiligase, an Enzyme for Efficient Chemo-Enzymatic Peptide Synthesis (Ceps) of Aviptadil

Mahmoudzadeh, K., Habibi, Z., Yousefi, M., Mostafavi, M., & Mohammadi, M. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.127089 · Cited by 4 · see citing works

High levels of REV7 expression are associated with poor prognosis and chemoresistance in gastric adenocarcinoma

Kesen, Y., Ichinoe, M., Hayashi, S., Umezawa, A., Numata, Y., Kogami, T., Matsushita, M., Sanoyama, I., Hoshino, A., Sakurai, Y., et al. (2024) · Pathology International · doi:10.1111/pin.13504 · Cited by 1 · see citing works

Rev1-Rev7 Complex Inhibitor JH-RE-06 Enhances Mitomycin C Chemosensitivity in HCT116 Colorectal Cancer CellsPreprint

Cheng, J., Sun, H., Ma, W., Yu, J., Hao, Y., Wang, F., Li, X., Wang, H., Ling, J., & Xu, F. (2023) · Research Square · doi:10.21203/rs.3.rs-3071400/v1 · Cited by 1 · see citing works

Structural Basis of the Multifunctional Hub Protein and Identification of a Small-molecule Compound for Drug Discovery

Hara, K. (2019) · YAKUGAKU ZASSHI · doi:10.1248/yakushi.19-00092

Study on antibacterial activity and self-assembly of ovalbumin-derived peptides

Tan, A., & Konno, H. (2021) · E3S Web of Conferences · doi:10.1051/e3sconf/202124503056

Interview of George Toney by Dian O. Belanger

Toney, G. (2009) · The Knowledge Bank (The Ohio State University)

Ganoboninketal C from Ganoderma boninenseimproves the efficacy of CDDP-based chemotherapy through inhibiting translesion DNA synthesis

Ma, X., Yang, F., Ma, K., Shen, H., Han, J., Wang, K., Yang, Y., Zhu, J., An, R., Wang, Q., et al. (2023) · Food Science and Human Wellness · doi:10.26599/fshw.2022.9250241

Probing hot spots of protein-protein interactions mediated by the safety-belt region of REV7

Dash, R. C., Arianna, G. A., Patel, S. M., Rizzo, A. A., Harrahill, N. J., Korzhnev, D. M., & Hadden, M. K. (2024) · Structure · doi:10.1016/j.str.2024.09.007

Significance of REV7 Expression in p16‐Negative Oropharyngeal Squamous Cell Carcinoma

Momiyama, K., Tsutsumi, S., Sakurai, Y., Mogi, S., Miyamoto, S., Murakumo, Y., & Yamashita, T. (2024) · Head & Neck · doi:10.1002/hed.28015

Regulation of the DNA polymerase zeta in response to genotoxic stress in mammalian cells

Goulas, J. (2025) · doi:10.70675/7894ebf5zbdf7z4147z940ezc553e0ed0e18

Two Secondary Introductions From a Shared Bridgehead Population Show Evidence of Divergent and Parallel Selection

Nugroho, A., Comte, S., Barrière, P., Allen, R. B., Sherwin, W. B., & Rollins, L. A. (2026) · Molecular Ecology · doi:10.1111/mec.70495

BindingDB Entry 50014902: N-(4-acetamidophenyl)-5-acetylfuran-2-carboxamide as a novel orally available diuretic that targets urea transporters with improved PD and PK properties.

BindingDB (2023) · UC San Diego · doi:10.7270/q2gh9nsq

Docking‐Based Virtual Screening Identifies a Small‐Molecule Inhibitor of the Translesion Synthesis REV7/REV3 Protein–Protein Interaction

Harrahill, N. J., Patel, S. M., Dash, R. C., Zaino, A. M., Gupta, V., Geddes-Buehre, D. H., Brereton, C., Rizzo, A. A., Chatterjee, N., Korzhnev, D. M., et al. (2026) · ChemMedChem · doi:10.1002/cmdc.70427

Virtual Pharmacophore Screening Identifies Small‐Molecule Inhibitors of the Rev1‐CT/RIR Protein–Protein Interaction

Dash, R. C., Ozen, Z., McCarthy, K. R., Chatterjee, N., Harris, C. A., Rizzo, A. A., Walker, G. C., Korzhnev, D. M., & Hadden, M. K. (2019) · ChemMedChem · doi:10.1002/cmdc.201900307 · Cited by 15 · see citing works

The Induction and Repair of DNA Interstrand Crosslinks and Implications in Cancer Chemotherapy

Guohui, S., Lijiao, Z., & Ru-gang, Z. (2015) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/1871520615666150824160421 · Cited by 25 · see citing works

Using synthetic DNA interstrand crosslinks to elucidate repair pathways and identify new therapeutic targets for cancer chemotherapy

Guainazzi, A., & Schärer, O. D. (2010) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-010-0492-6 · Cited by 70 · see citing works

REV1-POL ζ Inhibition and Cancer Therapy

Taniguchi, T. (2019) · Molecular Cell · doi:10.1016/j.molcel.2019.07.012 · Cited by 12 · see citing works