Roush, William R.

Targeting the NLRP3 inflammasome in inflammatory diseases

Mangan, M. S. J., Olhava, E. J., Roush, W. R., Seidel, H. M., Glick, G. D., & Latz, E. (2018) · Nature Reviews Drug Discovery

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 1,885

Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand

Solt, L. A., Kumar, N., Nuhant, P., Wang, Y., Lauer, J. L., Liu, J., Istrate, M. A., Kamenecka, T. M., Roush, W. R., Vidović, D., et al. (2011) · Nature

Psoriasis: Treatment and PathogenesisT-cell and B-cell Immunology

Cited by 508

Erratum: Targeting the NLRP3 inflammasome in inflammatory diseases

Mangan, M. S. J., Olhava, E. J., Roush, W. R., Seidel, H. M., Glick, G. D., & Latz, E. (2018) · Nature Reviews Drug Discovery

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 465

Therapeutic Targeting of CDK12/CDK13 in Triple-Negative Breast Cancer

Quereda, V., Bayle, S., Vena, F., Frydman, S. M., Monastyrskyi, A., Roush, W. R., & Duckett, D. R. (2019) · Cancer Cell

PARP inhibition in cancer therapyChromatin Remodeling and Cancer

Cited by 352

A Novel and Specific NADPH Oxidase-1 (Nox1) Small-Molecule Inhibitor Blocks the Formation of Functional Invadopodia in Human Colon Cancer Cells

Gianni, D., Taulet, N., Zhang, H., DerMardirossian, C., Kister, J., Martinez, L., Roush, W. R., Brown, S. J., Bokoch, G. M., & Rosen, H. (2010) · ACS Chemical Biology

Redox biology and oxidative stressNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 192

Identification of Histone Deacetylase Inhibitors with Benzoylhydrazide Scaffold that Selectively Inhibit Class I Histone Deacetylases

Wang, Y., Stowe, R. L., Pinello, C. E., Tian, G., Madoux, F., Li, D., Zhao, L. Y., Li, J.-L., Wang, Y., Wang, Y., et al. (2015) · Chemistry & Biology

Histone Deacetylase Inhibitors ResearchHeterocyclic Compound Synthesis and Bioactivity

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Abstract 4718: SR-4370, a potent and selective inhibitor of class I HDACs, suppresses AR signaling and in vivo prostate tumor growth

Mahmud, I., Tian, G., Wang, J., Stowe, R., Huo, Z., Zhang, Y., Purayil, H. T., Helm, E., Drashansky, T., Avram, D., et al. (2019) · Cancer Research

Histone Deacetylase Inhibitors ResearchProstate Cancer Treatment and Research

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