Boretto, Matteo

Development of organoids from mouse and human endometrium showing endometrial epithelium physiology and long-term expandability

Boretto, M., Cox, B., Noben, M., Hendriks, N., Fassbender, A., Roose, H., Amant, F., Timmerman, D., Tomassetti, C., Vanhie, A., et al. (2017) · Development

Reproductive Biology and FertilityReproductive System and Pregnancy

Cited by 459

Developing Organoids from Ovarian Cancer as Experimental and Preclinical Models

Maenhoudt, N., Defraye, C., Boretto, M., Jan, Z., Heremans, R., Boeckx, B., Hermans, F., Arijs, I., Cox, B., Van Nieuwenhuysen, E., et al. (2020) · Stem Cell Reports

Ovarian cancer diagnosis and treatmentCancer Cells and Metastasis

Cited by 186

Evaluating CRISPR-based prime editing for cancer modeling and CFTR repair in organoids

Geurts, M. H., de Poel, E., Pleguezuelos-Manzano, C., Oka, R., Carrillo, L., Andersson-Rolf, A., Boretto, M., Brunsveld, J. E., van Boxtel, R., Beekman, J. M., et al. (2021) · Life Science Alliance

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 151

One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids

Geurts, M. H., Gandhi, S., Boretto, M. G., Akkerman, N., Derks, L. L. M., van Son, G., Celotti, M., Harshuk-Shabso, S., Peci, F., Begthel, H., et al. (2023) · Nature Communications

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 66

Epidermal growth factor receptor (EGFR) is a target of the tumor-suppressor E3 ligase FBXW7

Boretto, M., Geurts, M. H., Gandhi, S., Ma, Z., Staliarova, N., Celotti, M., Lim, S., He, G.-W., Millen, R., Driehuis, E., et al. (2024) · Proceedings of the National Academy of Sciences

Ubiquitin and proteasome pathwaysHER2/EGFR in Cancer Research

Cited by 30