Sergeant, Nicolas

The biochemical pathway of neurofibrillary degeneration in aging and Alzheimer's disease.

Delacourte, A., David, J. P., Sergeant, N., Buée, L., Wattez, A., Vermersch, P., Ghozali, F., Fallet-Bianco, C., Pasquier, F., Lebert, F., et al. (1999) · Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 828

Nuclear Tau, a Key Player in Neuronal DNA Protection

Sultan, A., Nesslany, F., Violet, M., Bégard, S., Loyens, A., Talahari, S., Mansuroglu, Z., Marzin, D., Sergeant, N., Humez, S., et al. (2011) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsHeat shock proteins research

Cited by 421

Massive CA1/2 Neuronal Loss with Intraneuronal and N-Terminal Truncated Aβ42 Accumulation in a Novel Alzheimer Transgenic Model

Casas, C., Sergeant, N., Itier, J.-M., Blanchard, V., Wirths, O., van der Kolk, N., Vingtdeux, V., van de Steeg, E., Ret, G., Canton, T., et al. (2004) · The American Journal of Pathology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 400

Biochemistry of Tau in Alzheimer’s disease and related neurological disorders

Sergeant, N., Bretteville, A., Hamdane, M., Caillet-Boudin, M.-L., Grognet, P., Bombois, S., Blum, D., Delacourte, A., Pasquier, F., Vanmechelen, E., et al. (2008) · Expert Review of Proteomics

Alzheimer's disease research and treatmentsAdvanced Proteomics Techniques and Applications

Cited by 300

Tau Phosphorylation and Sevoflurane Anesthesia: An Association to Postoperative Cognitive Impairment

Le Freche, H., Brouillette, J., Fernandez-Gomez, F.-J., Patin, P., Caillierez, R., Zommer, N., Sergeant, N., Buée-Scherrer, V., Lebuffe, G., Blum, D., et al. (2012) · Anesthesiology

Anesthesia and Neurotoxicity ResearchAlzheimer's disease research and treatments

Cited by 212

Targeting Phospho-Ser422 by Active Tau Immunotherapy in the THYTau22 Mouse Model: A Suitable Therapeutic Approach

Zommer, N., Sergeant, N., Schraen-Maschke, S., Blum, D., & Buee, L. (2012) · Current Alzheimer Research

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 193

MBNL Sequestration by Toxic RNAs and RNA Misprocessing in the Myotonic Dystrophy Brain

Goodwin, M., Mohan, A., Batra, R., Lee, K.-Y., Charizanis, K., Gómez, F. J. F., Eddarkaoui, S., Sergeant, N., Buée, L., Kimura, T., et al. (2015) · Cell Reports

RNA Research and SplicingGenetic Neurodegenerative Diseases

Cited by 151

Differential Mass Spectrometry Profiles of Tau Protein in the Cerebrospinal Fluid of Patients with Alzheimer’s Disease, Progressive Supranuclear Palsy, and Dementia with Lewy Bodies

Barthélemy, N. R., Gabelle, A., Hirtz, C., Fenaille, F., Sergeant, N., Schraen-Maschke, S., Vialaret, J., Buée, L., Junot, C., Becher, F., et al. (2016) · Journal of Alzheimer’s Disease

Alzheimer's disease research and treatmentsAdvanced Proteomics Techniques and Applications

Cited by 139

Tau Protein Quantification in Human Cerebrospinal Fluid by Targeted Mass Spectrometry at High Sequence Coverage Provides Insights into Its Primary Structure Heterogeneity

Barthélemy, N. R., Fenaille, F., Hirtz, C., Sergeant, N., Schraen-Maschke, S., Vialaret, J., Buée, L., Gabelle, A., Junot, C., Lehmann, S., et al. (2016) · Journal of Proteome Research

Alzheimer's disease research and treatmentsAdvanced Proteomics Techniques and Applications

Cited by 123

Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology

Dourlen, P., Fernandez-Gomez, F. J., Dupont, C., Grenier-Boley, B., Bellenguez, C., Obriot, H., Caillierez, R., Sottejeau, Y., Chapuis, J., Bretteville, A., et al. (2017) · Molecular Psychiatry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 118

Different distribution of phosphorylated tau protein isoforms in Alzheimer's and Pick's diseases

Sergeant, N., David, J.-P., Lefranc, D., Vermersch, P., Wattez, A., & Delacourte, A. (1997) · FEBS Letters

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 117

Potential Contribution of Exosomes to the Prion-Like Propagation of Lesions in Alzheimer’s Disease

Vingtdeux, V., Sergeant, N., & Buée, L. (2012) · Frontiers in Physiology

Alzheimer's disease research and treatmentsExtracellular vesicles in disease

Cited by 116

Argyrophilic grain disease and Alzheimer's disease are distinguished by their different distribution of tau protein isoforms

Tolnay, M., Sergeant, N., Ghestem, A., Chalbot, S., de Vos, R. A., Jansen Steur, E. N., Probst, A., & Delacourte, A. (2002) · Acta Neuropathologica

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 89

Phosphorylated serine 199 of microtubule-associated protein tau is a neuronal epitope abundantly expressed in youth and an early marker of tau pathology

Maurage, C.-A., Sergeant, N., Ruchoux, M.-M., Hauw, J.-J., & Delacourte, A. (2003) · Acta Neuropathologica

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 51