Cheng, Jingdong

Collided ribosomes form a unique structural interface to induce Hel2-driven quality control pathways

Ikeuchi, K., Tesina, P., Matsuo, Y., Sugiyama, T., Cheng, J., Saeki, Y., Tanaka, K., Becker, T., Beckmann, R., & Inada, T. (2019) · The EMBO Journal

RNA and protein synthesis mechanismsUbiquitin and proteasome pathways

Cited by 315

Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation.

Cheng, J., Yang, H., Fang, J., Ma, L., Gong, R., Wang, P., Li, Z., & Xu, Y. (2015) · Nature Communications

Epigenetics and DNA MethylationUbiquitin and proteasome pathways

Cited by 158

RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1

Matsuo, Y., Tesina, P., Nakajima, S., Mizuno, M., Endo, A., Buschauer, R., Cheng, J., Shounai, O., Ikeuchi, K., Saeki, Y., et al. (2020) · Nature Structural & Molecular Biology

RNA and protein synthesis mechanismsUbiquitin and proteasome pathways

Cited by 150

Crystal structure of the Gtr1p–Gtr2p complex reveals new insights into the amino acid-induced TORC1 activation

Gong, R., Li, L., Liu, Y., Wang, P., Yang, H., Wang, L., Cheng, J., Guan, K.-L., & Xu, Y. (2011) · Genes & Development

PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling

Cited by 98

Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel

Osterman, I. A., Wieland, M., Maviza, T. P., Lashkevich, K. A., Lukianov, D. A., Komarova, E. S., Zakalyukina, Y. V., Buschauer, R., Shiriaev, D. I., Leyn, S. A., et al. (2020) · Nature Chemical Biology

RNA and protein synthesis mechanismsMicrobial Natural Products and Biosynthesis

Cited by 75

Structural basis of INTAC-regulated transcription

Zheng, H., Jin, Q., Qi, Y., Liu, W., Ren, Y., Wang, X., Chen, F., Cheng, J., Chen, X., & Xu, Y. (2021) · Protein & Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 45

Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline

Li, X., Wang, M., Denk, T., Buschauer, R., Li, Y., Beckmann, R., & Cheng, J. (2024) · Nature Communications

RNA and protein synthesis mechanismsRNA modifications and cancer

Cited by 21