Botha, Hugo

The bivariate distribution of amyloid-β and tau: relationship with established neurocognitive clinical syndromes

Jack, C. R., Wiste, H. J., Botha, H., Weigand, S. D., Therneau, T. M., Knopman, D. S., Graff-Radford, J., Jones, D. T., Ferman, T. J., Boeve, B. F., et al. (2019) · Brain

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

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Progressive dysexecutive syndrome due to Alzheimer's disease: a description of 55 cases and comparison to other phenotypes

Townley, R. A., Graff-Radford, J., Mantyh, W. G., Botha, H., Polsinelli, A. J., Przybelski, S. A., Machulda, M. M., Makhlouf, A. T., Senjem, M. L., Murray, M. E., et al. (2020) · Brain Communications

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 145

Temporal order of clinical and biomarker changes in familial frontotemporal dementia

Staffaroni, A. M., Quintana, M., Wendelberger, B., Heuer, H. W., Russell, L. L., Cobigo, Y., Wolf, A., Goh, S.-Y. M., Petrucelli, L., Gendron, T. F., et al. (2022) · Nature Medicine

Dementia and Cognitive Impairment ResearchAmyotrophic Lateral Sclerosis Research

Cited by 140

Predicting future rates of tau accumulation on PET

Jack, C. R., Wiste, H. J., Weigand, S. D., Therneau, T. M., Lowe, V. J., Knopman, D. S., Botha, H., Graff-Radford, J., Jones, D. T., Ferman, T. J., et al. (2020) · Brain

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 117

Primary progressive aphasias and apraxia of speech

Botha, H., & Josephs, K. A. (2019) · Continuum

Dementia and Cognitive Impairment ResearchNeurobiology of Language and Bilingualism

Cited by 95

A computational model of neurodegeneration in Alzheimer’s disease

Jones, D., Lowe, V., Graff-Radford, J., Botha, H., Barnard, L., Wiepert, D., Murphy, M. C., Murray, M., Senjem, M., Gunter, J., et al. (2022) · Nature Communications

Dementia and Cognitive Impairment ResearchFunctional Brain Connectivity Studies

Cited by 78

Comprehensive cross-sectional and longitudinal analyses of plasma neurofilament light across FTD spectrum disorders

Gendron, T. F., Heckman, M. G., White, L. J., Veire, A. M., Pedraza, O., Burch, A. R., Bozoki, A. C., Dickerson, B. C., Domoto-Reilly, K., Foroud, T., et al. (2022) · Cell Reports Medicine

Dementia and Cognitive Impairment ResearchAmyotrophic Lateral Sclerosis Research

Cited by 70

Sensitivity–Specificity of Tau and Amyloid β Positron Emission Tomography in Frontotemporal Lobar Degeneration

Ghirelli, A., Tosakulwong, N., Weigand, S. D., Clark, H. M., Ali, F., Botha, H., Duffy, J. R., Utianski, R. L., Buciuc, M., Murray, M. E., et al. (2020) · Annals of Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 59

Progressive agrammatic aphasia without apraxia of speech as a distinct syndrome

Tetzloff, K. A., Duffy, J. R., Clark, H. M., Utianski, R. L., Strand, E. A., Machulda, M. M., Botha, H., Martin, P. R., Schwarz, C. G., Senjem, M. L., et al. (2019) · Brain

Dementia and Cognitive Impairment ResearchNeurobiology of Language and Bilingualism

Cited by 55

Longitudinal atrophy in prodromal dementia with Lewy bodies points to cholinergic degeneration

Kantarci, K., Nedelska, Z., Chen, Q., Senjem, M. L., Schwarz, C. G., Gunter, J. L., Przybelski, S. A., Lesnick, T. G., Kremers, W. K., Fields, J. A., et al. (2022) · Brain Communications

Dementia and Cognitive Impairment ResearchParkinson's Disease Mechanisms and Treatments

Cited by 39

The evolution of parkinsonism in primary progressive apraxia of speech: a 6-year longitudinal study

Seckin, Z. I., Duffy, J. R., Strand, E. A., Clark, H. M., Utianski, R. L., Machulda, M. M., Botha, H., Ali, F., Thu Pham, N. T., Lowe, V. J., et al. (2020) · Parkinsonism & Related Disorders

Parkinson's Disease Mechanisms and TreatmentsDementia and Cognitive Impairment Research

Cited by 36

Reliability and Validity of Smartphone Cognitive Testing for Frontotemporal Lobar Degeneration

Staffaroni, A. M., Clark, A. L., Taylor, J. C., Heuer, H. W., Sanderson-Cimino, M., Wise, A. B., Dhanam, S., Cobigo, Y., Wolf, A., Manoochehri, M., et al. (2024) · JAMA Network Open

Dementia and Cognitive Impairment ResearchHistorical and Modern Theater Studies

Cited by 28

An FDG-PET-based machine learning framework to support neurologic decision-making in Alzheimer disease and related disorders

Barnard, L., Botha, H., Corriveau-Lecavalier, N., Graff-Radford, J., Dicks, E., Gogineni, V., Zhang, G., Burkett, B. J., Johnson, D. R., Huls, S. J., et al. (2025) · Neurology

Dementia and Cognitive Impairment ResearchArtificial Intelligence in Healthcare and Education

Cited by 25

Towards cascading genetic risk in Alzheimer’s disease

Altmann, A., Aksman, L. M., Oxtoby, N. P., Young, A. L., ADNI, Weiner, M., Aisen, P., Petersen, R., Weiner, M., Aisen, P., et al. (2024) · Brain

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 18

Deep learning to quantify the pace of brain aging in relation to neurocognitive changes

Yin, C., Imms, P., Chowdhury, N. F., Chaudhari, N. N., Ping, H., Wang, H., Bogdan, P., Irimia, A., Initiative, T. A. D. N., Weiner, M., et al. (2025) · Proceedings of the National Academy of Sciences

Dementia and Cognitive Impairment ResearchAdvanced MRI Techniques and Applications

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