Smith, Malcolm A.

Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma

Yu, A. L., Gilman, A. L., Ozkaynak, M. F., London, W. B., Kreissman, S. G., Chen, H. X., Smith, M., Anderson, B., Villablanca, J. G., Matthay, K. K., et al. (2010) · New England Journal of Medicine

Neuroblastoma Research and TreatmentsGlioma Diagnosis and Treatment

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Deletion of IKZF1 and Prognosis in Acute Lymphoblastic Leukemia

Mullighan, C. G., Su, X., Zhang, J., Radtke, I., Phillips, L. A. A., Miller, C. B., Ma, J., Liu, W., Cheng, C., Schulman, B. A., et al. (2009) · New England Journal of Medicine

Acute Lymphoblastic Leukemia researchLymphoma Diagnosis and Treatment

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Outcomes for children and adolescents with cancer: challenges for the twenty-first century

Smith, M. A., Seibel, N. L., Altekruse, S. F., Ries, L. A. G., Melbert, D. L., O'Leary, M., Smith, F. O., & Reaman, G. H. (2010) · Journal of Clinical Oncology

Global Cancer Incidence and ScreeningAcute Lymphoblastic Leukemia research

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The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia

Liu, Y., Easton, J., Shao, Y., Maciaszek, J., Wang, Z., Wilkinson, M. R., McCastlain, K., Edmonson, M., Pounds, S. B., Shi, L., et al. (2017) · Nature Genetics

Acute Lymphoblastic Leukemia researchAcute Myeloid Leukemia Research

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Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours

Ma, X., Liu, Y., Liu, Y., Alexandrov, L. B., Edmonson, M. N., Gawad, C., Zhou, X., Li, Y., Rusch, M. C., Easton, J., et al. (2018) · Nature

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

Cited by 901

Declining childhood and adolescent cancer mortality

Smith, M. A., Altekruse, S. F., Adamson, P. C., Reaman, G. H., & Seibel, N. L. (2014) · Cancer

Global Cancer Incidence and ScreeningAcute Lymphoblastic Leukemia research

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The pediatric preclinical testing program: Description of models and early testing results

Houghton, P. J., Morton, C. L., Tucker, C., Payne, D., Favours, E., Cole, C., Gorlick, R., Kolb, E. A., Zhang, W., Lock, R., et al. (2007) · Pediatric Blood & Cancer

Acute Lymphoblastic Leukemia researchSarcoma Diagnosis and Treatment

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Design Issues of Randomized Phase II Trials and a Proposal for Phase II Screening Trials

Rubinstein, L. V., Korn, E. L., Freidlin, B., Hunsberger, S., Ivy, S. P., & Smith, M. A. (2005) · Journal of Clinical Oncology

Statistical Methods in Clinical TrialsOptimal Experimental Design Methods

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Toward a Drug Development Path That Targets Metastatic Progression in Osteosarcoma

Khanna, C., Fan, T. M., Gorlick, R., Helman, L. J., Kleinerman, E. S., Adamson, P. C., Houghton, P. J., Tap, W. D., Welch, D. R., Steeg, P. S., et al. (2014) · Clinical Cancer Research

Sarcoma Diagnosis and TreatmentCancer Cells and Metastasis

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New policies to address the global burden of childhood cancers

Sullivan, R., Kowalczyk, J. R., Agarwal, B., Ladenstein, R., Fitzgerald, E., Barr, R., Steliarova-Foucher, E., Magrath, I., Howard, S. C., Kruger, M., et al. (2013) · The Lancet Oncology

Advances in Oncology and RadiotherapyGlobal Cancer Incidence and Screening

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The B7-H3–Targeting Antibody–Drug Conjugate m276-SL-PBD Is Potently Effective Against Pediatric Cancer Preclinical Solid Tumor Models

Kendsersky, N. M., Lindsay, J., Kolb, E. A., Smith, M. A., Teicher, B. A., Erickson, S. W., Earley, E. J., Mosse, Y. P., Martinez, D., Pogoriler, J., et al. (2021) · Clinical Cancer Research

Cancer Immunotherapy and BiomarkersMonoclonal and Polyclonal Antibodies Research

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Evaluation of Alternative In Vivo Drug Screening Methodology: A Single Mouse Analysis

Murphy, B., Yin, H., Maris, J. M., Kolb, E. A., Gorlick, R., Reynolds, C. P., Kang, M. H., Keir, S. T., Kurmasheva, R. T., Dvorchik, I., et al. (2016) · Cancer Research

Animal testing and alternativesCancer Cells and Metastasis

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MYCN controls an alternative RNA splicing program in high-risk metastatic neuroblastoma

Zhang, S., Wei, J. S., Li, S. Q., Badgett, T. C., Song, Y. K., Agarwal, S., Coarfa, C., Tolman, C., Hurd, L., Liao, H., et al. (2016) · Cancer Letters

Neuroblastoma Research and TreatmentsRNA Research and Splicing

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ABBV-085, Antibody–Drug Conjugate Targeting LRRC15, Is Effective in Osteosarcoma: A Report by the Pediatric Preclinical Testing Consortium

Hingorani, P., Roth, M. E., Wang, Y., Zhang, W., Gill, J. B., Harrison, D. J., Teicher, B., Erickson, S., Gatto, G., Smith, M. A., et al. (2021) · Molecular Cancer Therapeutics

Sarcoma Diagnosis and TreatmentMonoclonal and Polyclonal Antibodies Research

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Comprehensive Surfaceome Profiling to Identify and Validate Novel Cell-Surface Targets in Osteosarcoma

Wang, Y., Tian, X., Zhang, W., Zhang, Z., Lazcano, R., Hingorani, P., Roth, M. E., Gill, J. D., Harrison, D. J., Xu, Z., et al. (2022) · Molecular Cancer Therapeutics

Sarcoma Diagnosis and TreatmentAdvanced Proteomics Techniques and Applications

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Initial Testing (Stage 1) of MK‐8242—A Novel MDM2 Inhibitor—by the Pediatric Preclinical Testing Program

Kang, M. H., Reynolds, C. P., Kolb, E. A., Gorlick, R., Carol, H., Lock, R., Keir, S. T., Maris, J. M., Wu, J., Lyalin, D., et al. (2016) · Pediatric Blood & Cancer

Cancer-related Molecular PathwaysCancer Mechanisms and Therapy

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Trastuzumab Deruxtecan, Antibody–Drug Conjugate Targeting HER2, Is Effective in Pediatric Malignancies: A Report by the Pediatric Preclinical Testing Consortium

Hingorani, P., Zhang, W., Zhang, Z., Xu, Z., Wang, W.-L., Roth, M. E., Wang, Y., Gill, J. B., Harrison, D. J., Teicher, B. A., et al. (2022) · Molecular Cancer Therapeutics

HER2/EGFR in Cancer ResearchMonoclonal and Polyclonal Antibodies Research

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Initial testing of JNJ‐26854165 (Serdemetan) by the pediatric preclinical testing program

Smith, M. A., Gorlick, R., Kolb, E. A., Lock, R., Carol, H., Maris, J. M., Keir, S. T., Morton, C. L., Reynolds, C. P., Kang, M. H., et al. (2012) · Pediatric Blood & Cancer

Cancer-related Molecular PathwaysAcute Lymphoblastic Leukemia research

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Paediatric Strategy Forum for medicinal product development of multi-targeted kinase inhibitors in bone sarcomas

Pearson, A. D., Gaspar, N., Janeway, K., Campbell-Hewson, Q., Lawlor, E. R., Copland, C., Karres, D., Norga, K., Benzaghou, F., Weiner, S., et al. (2022) · European Journal of Cancer

Sarcoma Diagnosis and TreatmentPharmaceutical studies and practices

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Abstract LB-217: Preclinical evaluation of trastuzumab deruxtecan (T-DXd; DS-8201a), a HER2 antibody-drug conjugate, in pediatric solid tumors by the Pediatric Preclinical Testing Consortium (PPTC)

Hingorani, P., Zhang, W., Kurmasheva, R., Zhang, Z., Wang, Y., Xu, Z., Roth, M., Gill, J., Harrison, D., Erickson, S., et al. (2020) · Cancer Research

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