Screpanti, Isabella

Lymphoproliferative disorder and imbalanced T-helper response in C/EBP beta-deficient mice

Screpanti, I., Romani, L., Musiani, P., Modesti, A., Fattori, E., Lazzaro, D., Sellitto, C., Scarpa, S., Bellavia, D., & Lattanzio, G. (1995) · The EMBO Journal

T-cell and B-cell ImmunologyCytokine Signaling Pathways and Interactions

Cited by 407

Histone deacetylase and Cullin3–RENKCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation

Canettieri, G., Di Marcotullio, L., Greco, A., Coni, S., Antonucci, L., Infante, P., Pietrosanti, L., De Smaele, E., Ferretti, E., Miele, E., et al. (2010) · Nature Cell Biology

Hedgehog Signaling Pathway StudiesHistone Deacetylase Inhibitors Research

Cited by 322

Heterozygous germline mutations in the CBL tumor-suppressor gene cause a Noonan syndrome-like phenotype

Martinelli, S., De Luca, A., Stellacci, E., Rossi, C., Checquolo, S., Lepri, F., Caputo, V., Silvano, M., Buscherini, F., Consoli, F., et al. (2010) · The American Journal of Human Genetics

Protein Tyrosine PhosphatasesGenomics and Rare Diseases

Cited by 259

REN KCTD11 is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma

Di Marcotullio, L., Ferretti, E., De Smaele, E., Argenti, B., Mincione, C., Zazzeroni, F., Gallo, R., Masuelli, L., Napolitano, M., Maroder, M., et al. (2004) · Proceedings of the National Academy of Sciences

Hedgehog Signaling Pathway StudiesGlioma Diagnosis and Treatment

Cited by 179

Identification and Characterization of KCASH2 and KCASH3, 2 Novel Cullin3 Adaptors Suppressing Histone Deacetylase and Hedgehog Activity in Medulloblastoma

De Smaele, E., Di Marcotullio, L., Moretti, M., Pelloni, M., Occhione, M. A., Infante, P., Cucchi, D., Greco, A., Pietrosanti, L., Todorovic, J., et al. (2011) · Neoplasia

Hedgehog Signaling Pathway StudiesGlioma Diagnosis and Treatment

Cited by 92

Notch3 and the Notch3‐upregulated RNA‐binding protein HuD regulate Ikaros alternative splicing

Bellavia, D., Mecarozzi, M., Campese, A. F., Grazioli, P., Talora, C., Frati, L., Gulino, A., & Screpanti, I. (2007) · The EMBO Journal

Developmental Biology and Gene RegulationGenomics and Chromatin Dynamics

Cited by 80

Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma

Coni, S., Mancuso, A. B., Di Magno, L., Sdruscia, G., Manni, S., Serrao, S. M., Rotili, D., Spiombi, E., Bufalieri, F., Petroni, M., et al. (2017) · Scientific Reports

Hedgehog Signaling Pathway StudiesHistone Deacetylase Inhibitors Research

Cited by 75

Hedgehog Antagonist RENKCTD11Regulates Proliferation and Apoptosis of Developing Granule Cell Progenitors

Argenti, B., Gallo, R., Di Marcotullio, L., Ferretti, E., Napolitano, M., Canterini, S., De Smaele, E., Greco, A., Fiorenza, M. T., Maroder, M., et al. (2005) · The Journal of Neuroscience

Hedgehog Signaling Pathway StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 73