Chowdhury, Rasheduzzaman

The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases

Chowdhury, R., Yeoh, K. K., Tian, Y., Hillringhaus, L., Bagg, E. A., Rose, N. R., Leung, I. K. H., Li, X. S., Woon, E. C. Y., Yang, M., et al. (2011) · The EMBO Reports

Cancer, Hypoxia, and MetabolismEpigenetics and DNA Methylation

Cited by 1,035

2-Oxoglutarate-Dependent Oxygenases

Islam, M. S., Leissing, T. M., Chowdhury, R., Hopkinson, R. J., & Schofield, C. J. (2018) · Annual Review of Biochemistry

Metal-Catalyzed Oxygenation MechanismsBiochemical Acid Research Studies

Cited by 472

Structural studies on human 2-oxoglutarate dependent oxygenases

McDonough, M. A., Loenarz, C., Chowdhury, R., Clifton, I. J., & Schofield, C. J. (2010) · Current Opinion in Structural Biology

Metal-Catalyzed Oxygenation MechanismsEnzyme Structure and Function

Cited by 280

Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans

Ge, W., Wolf, A., Feng, T., Ho, C.-H., Sekirnik, R., Zayer, A., Granatino, N., Cockman, M. E., Loenarz, C., Loik, N. D., et al. (2012) · Nature Chemical Biology

RNA and protein synthesis mechanismsRNA modifications and cancer

Cited by 154

Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases

Chowdhury, R., Leung, I. K. H., Tian, Y.-M., Abboud, M. I., Ge, W., Domene, C., Cantrelle, F.-X., Landrieu, I., Hardy, A. P., Pugh, C. W., et al. (2016) · Nature Communications

Cancer, Hypoxia, and MetabolismMetal-Catalyzed Oxygenation Mechanisms

Cited by 145

Ribosomal oxygenases are structurally conserved from prokaryotes to humans

Chowdhury, R., Sekirnik, R., Brissett, N. C., Krojer, T., Ho, C.-H., Ng, S. S., Clifton, I. J., Ge, W., Kershaw, N. J., Fox, G. C., et al. (2014) · Nature

Metal-Catalyzed Oxygenation MechanismsEnzyme Structure and Function

Cited by 105