Park, Laibaik

Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer’s disease mouse models

Cruz Hernández, J. C., Bracko, O., Kersbergen, C. J., Muse, V., Haft-Javaherian, M., Berg, M., Park, L., Vinarcsik, L. K., Ivasyk, I., Rivera, D. A., et al. (2019) · Nature Neuroscience

Alzheimer's disease research and treatmentsBarrier Structure and Function Studies

Cited by 508

Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein

Park, L., Zhou, P., Pitstick, R., Capone, C., Anrather, J., Norris, E. H., Younkin, L., Younkin, S., Carlson, G., McEwen, B. S., et al. (2008) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsNeurological Disease Mechanisms and Treatments

Cited by 332

Nox2-Derived Reactive Oxygen Species Mediate Neurovascular Dysregulation in the Aging Mouse Brain

Park, L., Anrather, J., Girouard, H., Zhou, P., & Iadecola, C. (2007) · Journal of Cerebral Blood Flow & Metabolism

Nitric Oxide and Endothelin EffectsNeurological Disease Mechanisms and Treatments

Cited by 275

Brain Perivascular Macrophages Initiate the Neurovascular Dysfunction of Alzheimer Aβ Peptides

Park, L., Uekawa, K., Garcia-Bonilla, L., Koizumi, K., Murphy, M., Pistik, R., Younkin, L., Younkin, S., Zhou, P., Carlson, G., et al. (2017) · Circulation Research

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 259

NADPH Oxidase-Derived Reactive Oxygen Species Mediate the Cerebrovascular Dysfunction Induced by the Amyloid β Peptide

Park, L., Anrather, J., Zhou, P., Frys, K., Pitstick, R., Younkin, S., Carlson, G. A., & Iadecola, C. (2005) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsNitric Oxide and Endothelin Effects

Cited by 244

Threats to the Mind: Aging, Amyloid, and Hypertension

Iadecola, C., Park, L., & Capone, C. (2009) · Stroke

Neurological Disease Mechanisms and TreatmentsNitric Oxide and Endothelin Effects

Cited by 207

Brain perivascular macrophages: characterization and functional roles in health and disease

Faraco, G., Park, L., Anrather, J., & Iadecola, C. (2017) · Journal of Molecular Medicine

Neuroinflammation and Neurodegeneration MechanismsBarrier Structure and Function Studies

Cited by 206

Apoε4 disrupts neurovascular regulation and undermines white matter integrity and cognitive function

Koizumi, K., Hattori, Y., Ahn, S. J., Buendia, I., Ciacciarelli, A., Uekawa, K., Wang, G., Hiller, A., Zhao, L., Voss, H. U., et al. (2018) · Nature Communications

Neurological Disease Mechanisms and TreatmentsCerebrovascular and genetic disorders

Cited by 179

Hypertension enhances A β -induced neurovascular dysfunction, promotes β -secretase activity, and leads to amyloidogenic processing of APP

Faraco, G., Park, L., Zhou, P., Luo, W., Paul, S. M., Anrather, J., & Iadecola, C. (2016) · Journal of Cerebral Blood Flow & Metabolism

Alzheimer's disease research and treatmentsNeurological Disease Mechanisms and Treatments

Cited by 158

Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-β

Park, L., Wang, G., Zhou, P., Zhou, J., Pitstick, R., Previti, M. L., Younkin, L., Younkin, S. G., Van Nostrand, W. E., Cho, S., et al. (2011) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsBarrier Structure and Function Studies

Cited by 156

The cerebrovascular dysfunction induced by slow pressor doses of angiotensin II precedes the development of hypertension

Capone, C., Faraco, G., Park, L., Cao, X., Davisson, R. L., & Iadecola, C. (2011) · American Journal of Physiology-Heart and Circulatory Physiology

Renin-Angiotensin System StudiesNitric Oxide and Endothelin Effects

Cited by 136

Border-associated macrophages promote cerebral amyloid angiopathy and cognitive impairment through vascular oxidative stress

Uekawa, K., Hattori, Y., Ahn, S. J., Seo, J., Casey, N., Anfray, A., Zhou, P., Luo, W., Anrather, J., Park, L., et al. (2023) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 80

Hypoxia Inducible Factor-1α binds and activates γ-secretase for Aβ production under hypoxia and cerebral hypoperfusion

Alexander, C., Li, T., Hattori, Y., Chiu, D., Frost, G. R., Jonas, L., Liu, C., Anderson, C. J., Wong, E., Park, L., et al. (2022) · Molecular Psychiatry

Alzheimer's disease research and treatmentsNeurological Disease Mechanisms and Treatments

Cited by 64