Drakesmith, Hal

Hepcidin and the iron-infection axis

Drakesmith, H., & Prentice, A. M. (2012) · Science

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 686

Ironing out Ferroportin

Drakesmith, H., Nemeth, E., & Ganz, T. (2015) · Cell Metabolism

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 638

Viral infection and iron metabolism

Drakesmith, H., & Prentice, A. (2008) · Nature Reviews Microbiology

Iron Metabolism and DisordersTrace Elements in Health

Cited by 469

Control of iron deficiency anemia in low- and middle-income countries

Pasricha, S.-R., Drakesmith, H., Black, J., Hipgrave, D., & Biggs, B.-A. (2013) · Blood

Iron Metabolism and DisordersChild Nutrition and Water Access

Cited by 440

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

Ahern, D. J., Ai, Z., Ainsworth, M., Allan, C., Allcock, A., Angus, B., Ansari, M. A., Arancibia-Cárcamo, C. V., Aschenbrenner, D., Attar, M., et al. (2022) · Cell

COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 Research

Cited by 328

Hepcidin regulation by innate immune and infectious stimuli

Armitage, A. E., Eddowes, L. A., Gileadi, U., Cole, S., Spottiswoode, N., Selvakumar, T. A., Ho, L.-P., Townsend, A. R. M., & Drakesmith, H. (2011) · Blood

Iron Metabolism and DisordersCytokine Signaling Pathways and Interactions

Cited by 294

Erythroferrone inhibits the induction of hepcidin by BMP6

Arezes, J., Foy, N., McHugh, K., Sawant, A., Quinkert, D., Terraube, V., Brinth, A., Tam, M., LaVallie, E. R., Taylor, S., et al. (2018) · Blood

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 277

Resistance to hepcidin is conferred by hemochromatosis-associated mutations of ferroportin

Drakesmith, H., Schimanski, L. M., Ormerod, E., Merryweather-Clarke, A. T., Viprakasit, V., Edwards, J. P., Sweetland, E., Bastin, J. M., Cowley, D., Chinthammitr, Y., et al. (2005) · Blood

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 264

Host-mediated regulation of superinfection in malaria

Portugal, S., Carret, C., Recker, M., Armitage, A. E., Gonçalves, L. A., Epiphanio, S., Sullivan, D., Roy, C., Newbold, C. I., Drakesmith, H., et al. (2011) · Nature Medicine

Malaria Research and ControlBird parasitology and diseases

Cited by 232

In vitro functional analysis of human ferroportin (FPN) and hemochromatosis-associated FPN mutations

Schimanski, L. M., Drakesmith, H., Merryweather-Clarke, A. T., Viprakasit, V., Edwards, J. P., Sweetland, E., Bastin, J. M., Cowley, D., Chinthammitr, Y., Robson, K. J. H., et al. (2005) · Blood

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 212

Hepcidin is the major predictor of erythrocyte iron incorporation in anemic African children

Prentice, A. M., Doherty, C. P., Abrams, S. A., Cox, S. E., Atkinson, S. H., Verhoef, H., Armitage, A. E., & Drakesmith, H. (2012) · Blood

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 167

Could nutrition modulate COVID-19 susceptibility and severity of disease? A systematic review

James, P. T., Ali, Z., Armitage, A. E., Bonell, A., Cerami, C., Drakesmith, H., Jobe, M., Jones, K. S., Liew, Z., Moore, S. E., et al. (2020) · Journal of Nutrition

COVID-19 Clinical Research StudiesNutrition and Health in Aging

Cited by 147

The Role of Nutrition in COVID-19 Susceptibility and Severity of Disease: A Systematic Review

James, P. T., Ali, Z., Armitage, A. E., Bonell, A., Cerami, C., Drakesmith, H., Jobe, M., Jones, K. S., Liew, Z., Moore, S. E., et al. (2021) · The Journal of Nutrition

COVID-19 Clinical Research StudiesNutrition and Health in Aging

Cited by 147

Nrf2 controls iron homoeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin

Lim, P. J., Duarte, T. L., Arezes, J., Garcia-Santos, D., Hamdi, A., Pasricha, S.-R., Armitage, A. E., Mehta, H., Wideman, S., Santos, A. G., et al. (2019) · Nature Metabolism

Iron Metabolism and DisordersGenomics, phytochemicals, and oxidative stress

Cited by 147

The hemochromatosis protein HFE inhibits iron export from macrophages

Drakesmith, H., Sweetland, E., Schimanski, L., Edwards, J., Cowley, D., Ashraf, M., Bastin, J., & Townsend, A. R. M. (2002) · Proceedings of the National Academy of Sciences

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 128

Iron, anemia and hepcidin in malaria

Spottiswoode, N., Duffy, P. E., & Drakesmith, H. (2014) · Frontiers in Pharmacology

Iron Metabolism and DisordersMalaria Research and Control

Cited by 127

Why cells need iron: a compendium of iron utilisation

Teh, M. R., Armitage, A. E., & Drakesmith, H. (2024) · Trends in Endocrinology & Metabolism

Iron Metabolism and DisordersTrace Elements in Health

Cited by 114

Iron deficiency anemia at time of vaccination predicts decreased vaccine response and iron supplementation at time of vaccination increases humoral vaccine response: a birth cohort study and a randomized trial follow-up study in Kenyan infants

Stoffel, N. U., Uyoga, M. A., Mutuku, F. M., Frost, J. N., Mwasi, E., Paganini, D., van der Klis, F. R. M., Malhotra, I. J., LaBeaud, A. D., Ricci, C., et al. (2020) · Frontiers in Immunology

Iron Metabolism and DisordersImmune responses and vaccinations

Cited by 112

Expression of the iron hormone hepcidin distinguishes different types of anemia in African children

Pasricha, S.-R., Atkinson, S. H., Armitage, A. E., Khandwala, S., Veenemans, J., Cox, S. E., Eddowes, L. A., Hayes, T., Doherty, C. P., Demir, A. Y., et al. (2014) · Science Translational Medicine

Iron Metabolism and DisordersHemoglobinopathies and Related Disorders

Cited by 108

Distinct patterns of hepcidin and iron regulation during HIV-1, HBV, and HCV infections

Armitage, A. E., Stacey, A. R., Giannoulatou, E., Marshall, E., Sturges, P., Chatha, K., Smith, N. M. G., Huang, X., Xu, X., Pasricha, S.-R., et al. (2014) · Proceedings of the National Academy of Sciences

Iron Metabolism and DisordersHIV Research and Treatment

Cited by 101

Hepcidin is suppressed by erythropoiesis in hemoglobin E β-thalassemia and β-thalassemia trait

Jones, E., Pasricha, S.-R., Allen, A., Evans, P., Fisher, C. A., Wray, K., Premawardhena, A., Bandara, D., Perera, A., Webster, C., et al. (2015) · Blood

Hemoglobinopathies and Related DisordersIron Metabolism and Disorders

Cited by 68

Combinatorial effects of malaria season, iron deficiency and inflammation determine plasma hepcidin concentration in African children

Atkinson, S. H., Armitage, A. E., Khandwala, S., Mwangi, T. W., Uyoga, S., Bejon, P. A., Williams, T. N., Prentice, A. M., & Drakesmith, H. (2014) · Blood

Iron Metabolism and DisordersMalaria Research and Control

Cited by 64

The battle for iron in enteric infections

Sousa Gerós, A., Simmons, A., Drakesmith, H., Aulicino, A., & Frost, J. N. (2020) · Immunology

Iron Metabolism and DisordersGut microbiota and health

Cited by 58

Twenty Years of Ferroportin Disease: A Review or An Update of Published Clinical, Biochemical, Molecular, and Functional Features

Vlasveld, L. T., Janssen, R., Bardou-Jacquet, E., Venselaar, H., Hamdi-Roze, H., Drakesmith, H., & Swinkels, D. W. (2019) · Pharmaceuticals

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 57