Kinch, Lisa N.

Accurate prediction of protein structures and interactions using a 3-track network

Baek, M., DiMaio, F., Anishchenko, I., Dauparas, J., Ovchinnikov, S., Lee, G. R., Wang, J., Cong, Q., Kinch, L. N., Schaeffer, R. D., et al. (2021) · Science

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 5,549

Identification of a candidate therapeutic autophagy-inducing peptide

Shoji-Kawata, S., Sumpter, R., Leveno, M., Campbell, G. R., Zou, Z., Kinch, L., Wilkins, A. D., Sun, Q., Pallauf, K., MacDuff, D., et al. (2013) · Nature

Autophagy in Disease and TherapyRNA Interference and Gene Delivery

Cited by 760

An E3 ligase possessing an iron-responsive hemerythrin domain is a regulator of iron homeostasis

Salahudeen, A. A., Thompson, J. W., Ruiz, J. C., Ma, H.-W., Kinch, L. N., Li, Q., Grishin, N. V., & Bruick, R. K. (2009) · Science

Iron Metabolism and DisordersUbiquitin and proteasome pathways

Cited by 432

ECOD: an evolutionary classification of protein domains

Cheng, H., Schaeffer, R. D., Liao, Y., Kinch, L. N., Pei, J., Shi, S., Kim, B.-H., & Grishin, N. V. (2014) · PLoS Computational Biology

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 426

Structure, lipid scrambling activity and role in autophagosome formation of ATG9A

Maeda, S., Yamamoto, H., Kinch, L. N., Garza, C. M., Takahashi, S., Otomo, C., Grishin, N. V., Forli, S., Mizushima, N., & Otomo, T. (2020) · Nature Structural & Molecular Biology

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 305

Large-scale determination of previously unsolved protein structures using evolutionary information

Ovchinnikov, S., Kinch, L., Park, H., Liao, Y., Pei, J., Kim, D. E., Kamisetty, H., Grishin, N. V., & Baker, D. (2015) · eLife

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 222

Hyperactivation of TORC1 drives resistance to the pan-HER tyrosine kinase inhibitor neratinib in HER2-mutant cancers

Sudhan, D. R., Guerrero-Zotano, A., Won, H., González Ericsson, P., Servetto, A., Huerta-Rosario, M., Ye, D., Lee, K.-M., Formisano, L., Guo, Y., et al. (2020) · Cancer Cell

PI3K/AKT/mTOR signaling in cancerHER2/EGFR in Cancer Research

Cited by 49

CASP13 target classification into tertiary structure prediction categories

Kinch, L. N., Kryshtafovych, A., Monastyrskyy, B., & Grishin, N. V. (2019) · Proteins Structure Function and Bioinformatics

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 36

Co-Component Signal Transduction Systems: fast-evolving virulence regulation cassettes discovered in enteric bacteria

Kinch, L. N., Cong, Q., Jaishankar, J., & Orth, K. (2022) · Proceedings of the National Academy of Sciences

Bacterial Genetics and BiotechnologyEscherichia coli research studies

Cited by 25

ECOD domain classification of 48 whole proteomes from AlphaFold Structure Database using DPAM2

Schaeffer, R. D., Zhang, J., Medvedev, K. E., Kinch, L. N., Cong, Q., & Grishin, N. V. (2024) · PLOS Computational Biology

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 22

Structure classification of the proteins from Salmonella enterica pangenome revealed novel potential pathogenicity islands

Medvedev, K. E., Zhang, J., Schaeffer, R. D., Kinch, L. N., Cong, Q., & Grishin, N. V. (2024) · Scientific Reports

Salmonella and Campylobacter epidemiologyBacterial Genetics and Biotechnology

Cited by 11