Blobel, Gerd A.

A comparative encyclopedia of DNA elements in the mouse genome

Yue, F., Cheng, Y., Breschi, A., Vierstra, J., Wu, W., Ryba, T., Sandstrom, R., Ma, Z., Davis, C., Pope, B. D., et al. (2014) · Nature

Genomics and Chromatin DynamicsChromosomal and Genetic Variations

Cited by 1,781

Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor

Deng, W., Lee, J., Wang, H., Miller, J., Reik, A., Gregory, P. D., Dean, A., & Blobel, G. A. (2012) · Cell

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

Cited by 734

Proximity among Distant Regulatory Elements at the β-Globin Locus Requires GATA-1 and FOG-1

Vakoc, C. R., Letting, D. L., Gheldof, N., Sawado, T., Bender, M. A., Groudine, M., Weiss, M. J., Dekker, J., & Blobel, G. A. (2005) · Molecular Cell

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

Cited by 490

Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation

Shi, J., Whyte, W. A., Zepeda-Mendoza, C. J., Milazzo, J. P., Shen, C., Roe, J.-S., Minder, J. L., Mercan, F., Wang, E., Eckersley-Maslin, M. A., et al. (2013) · Genes & Development

Chromatin Remodeling and CancerGenomics and Chromatin Dynamics

Cited by 463

An encyclopedia of mouse DNA elements (Mouse ENCODE)

Mouse ENCODE Consortium, Stamatoyannopoulos, J. A., Snyder, M., Hardison, R., Ren, B., Gingeras, T., Gilbert, D. M., Groudine, M., Bender, M., Kaul, R., et al. (2012) · Genome Biology

Genomics and Chromatin DynamicsGenomics and Phylogenetic Studies

Cited by 446

Reactivation of developmentally silenced globin genes by forced chromatin looping

Deng, W., Rupon, J. W., Krivega, I., Breda, L., Motta, I., Jahn, K. S., Reik, A., Gregory, P. D., Rivella, S., Dean, A., et al. (2014) · Cell

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

Cited by 443

A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition

Traxler, E. A., Yao, Y., Wang, Y.-D., Woodard, K. J., Kurita, R., Nakamura, Y., Hughes, J. R., Hardison, R. C., Blobel, G. A., Li, C., et al. (2016) · Nature Medicine

Hemoglobinopathies and Related DisordersCRISPR and Genetic Engineering

Cited by 366

CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation

Blobel, G. A., Nakajima, T., Eckner, R., Montminy, M., & Orkin, S. H. (1998) · Proceedings of the National Academy of Sciences

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

Cited by 355

Enhancer Regulation of Transcriptional Bursting Parameters Revealed by Forced Chromatin Looping

Bartman, C. R., Hsu, S. C., Hsiung, C. C.-S., Raj, A., & Blobel, G. A. (2016) · Molecular Cell

Genomics and Chromatin DynamicsGene Regulatory Network Analysis

Cited by 345

GATA Transcription Factors and Cancer

Zheng, R., & Blobel, G. A. (2010) · Genes & Cancer

Genomics and Chromatin DynamicsCancer-related Molecular Pathways

Cited by 276

Chromatin structure dynamics during the mitosis-to-G1 phase transition

Zhang, H., Emerson, D. J., Gilgenast, T. G., Titus, K. R., Lan, Y., Huang, P., Zhang, D., Wang, H., Keller, C. A., Giardine, B., et al. (2019) · Nature

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 271

CREB-Binding Protein Acetylates Hematopoietic Transcription Factor GATA-1 at Functionally Important Sites

Hung, H.-L., Lau, J., Kim, A. Y., Weiss, M. J., & Blobel, G. A. (1999) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

Cited by 247

Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression

Cheng, Y., Wu, W., Ashok Kumar, S., Yu, D., Deng, W., Tripic, T., King, D. C., Chen, K.-B., Zhang, Y., Drautz, D., et al. (2009) · Genome Research

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

Cited by 223

Globin gene activation during haemopoiesis is driven by protein complexes nucleated by GATA‐1 and GATA‐2

Anguita, E., Hughes, J., Heyworth, C., Blobel, G. A., Wood, W. G., & Higgs, D. R. (2004) · The EMBO Journal

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

Cited by 207

Control of megakaryocyte‐specific gene expression by GATA‐1 and FOG‐1: role of Ets transcription factors

Wang, X., Crispino, J. D., Letting, D. L., Nakazawa, M., Poncz, M., & Blobel, G. A. (2002) · The EMBO Journal

Genomics and Chromatin DynamicsPlatelet Disorders and Treatments

Cited by 163

Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element

Huang, P., Keller, C. A., Giardine, B., Grevet, J. D., Davies, J. O. J., Hughes, J. R., Kurita, R., Nakamura, Y., Hardison, R. C., & Blobel, G. A. (2017) · Genes & Development

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

Cited by 127

Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration

Wu, W., Cheng, Y., Keller, C. A., Ernst, J., Kumar, S. A., Mishra, T., Morrissey, C., Dorman, C. M., Chen, K.-B., Drautz, D., et al. (2011) · Genome Research

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 118

Occupancy by key transcription factors is a more accurate predictor of enhancer activity than histone modifications or chromatin accessibility

Dogan, N., Wu, W., Morrissey, C. S., Chen, K.-B., Stonestrom, A., Long, M., Keller, C. A., Cheng, Y., Jain, D., Visel, A., et al. (2015) · Epigenetics & Chromatin

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 114

Insight into the Architecture of the NuRD Complex

Alqarni, S. S. M., Murthy, A., Zhang, W., Przewloka, M. R., Silva, A. P. G., Watson, A. A., Lejon, S., Pei, X. Y., Smits, A. H., Kloet, S. L., et al. (2014) · Journal of Biological Chemistry

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 84

Forced chromatin looping raises fetal hemoglobin in adult sickle cells to higher levels than pharmacologic inducers

Breda, L., Motta, I., Lourenco, S., Gemmo, C., Deng, W., Rupon, J. W., Abdulmalik, O. Y., Manwani, D., Blobel, G. A., & Rivella, S. (2016) · Blood

Hemoglobinopathies and Related DisordersVirus-based gene therapy research

Cited by 83

Inhibition of CBP-Mediated Protein Acetylation by the Ets Family Oncoprotein PU.1

Hong, W., Kim, A. Y., Ky, S., Rakowski, C., Seo, S.-B., Chakravarti, D., Atchison, M., & Blobel, G. A. (2002) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsAcute Myeloid Leukemia Research

Cited by 74

LDB1 establishes multi-enhancer networks to regulate gene expression

Aboreden, N. G., Lam, J. C., Goel, V. Y., Wang, S., Wang, X., Midla, S. C., Quijano, A., Keller, C. A., Giardine, B. M., Hardison, R. C., et al. (2025) · Molecular Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 61

Understanding heterogeneity of fetal hemoglobin induction through comparative analysis of F and A-erythroblasts

Khandros, E., Huang, P., Peslak, S. A., Sharma, M., Abdulmalik, O., Giardine, B. M., Zhang, Z., Keller, C. A., Hardison, R. C., & Blobel, G. A. (2020) · Blood

Hemoglobinopathies and Related DisordersHemoglobin structure and function

Cited by 40

Targeting the EIF2AK1 Signaling Pathway Rescues Red Blood Cell Production in SF3B1 -Mutant Myelodysplastic Syndromes With Ringed Sideroblasts

Adema, V., Ma, F., Kanagal-Shamanna, R., Thongon, N., Montalban-Bravo, G., Yang, H., Peslak, S. A., Wang, F., Acha, P., Sole, F., et al. (2022) · Blood Cancer Discovery

Acute Myeloid Leukemia ResearchRNA Research and Splicing

Cited by 20