Tönges, Lars
St. Josef-Hospital · Ruhr University Bochum
13 papers on CoChatORCID 0000-0001-6621-144X
Most cited papers
- Verified
Guidelines for the use and interpretation of assays for monitoring autophagy
Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy
Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism
Cited by 3,996
- Verified
Mechanisms of acute axonal degeneration in the optic nerve in vivo
Knöferle, J., Koch, J. C., Ostendorf, T., Michel, U., Planchamp, V., Vutova, P., Tönges, L., Stadelmann, C., Brück, W., Bähr, M., et al. (2010) · Proceedings of the National Academy of Sciences
Nerve injury and regenerationAutophagy in Disease and Therapy
Cited by 310
- Verified
ROCK inhibition in models of neurodegeneration and its potential for clinical translation
Koch, J. C., Tatenhorst, L., Roser, A.-E., Saal, K.-A., Tönges, L., & Lingor, P. (2018) · Pharmacology & Therapeutics
Protein Kinase Regulation and GTPase SignalingAlzheimer's disease research and treatments
Cited by 239
- Verified
ROCK2 is a major regulator of axonal degeneration, neuronal death and axonal regeneration in the CNS
Koch, J. C., Tönges, L., Barski, E., Michel, U., Bähr, M., & Lingor, P. (2014) · Cell Death & Disease
Nerve injury and regenerationAxon Guidance and Neuronal Signaling
Cited by 197
- Verified
Fasudil attenuates aggregation of α-synuclein in models of Parkinson’s disease
Tatenhorst, L., Eckermann, K., Dambeck, V., Fonseca-Ornelas, L., Walle, H., Lopes da Fonseca, T., Koch, J. C., Becker, S., Tönges, L., Bähr, M., et al. (2016) · Acta Neuropathologica Communications
Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling
Cited by 158
- Verified
Rho kinase inhibition modulates microglia activation and improves survival in a model of amyotrophic lateral sclerosis
Tönges, L., Günther, R., Suhr, M., Jansen, J., Balck, A., Saal, K., Barski, E., Nientied, T., Götz, A. A., Koch, J., et al. (2014) · Glia
Amyotrophic Lateral Sclerosis ResearchNeuroinflammation and Neurodegeneration Mechanisms
Cited by 121
- Verified
Axonal degeneration as a therapeutic target in the CNS
Lingor, P., Koch, J. C., Tönges, L., & Bähr, M. (2012) · Cell and Tissue Research
Nerve injury and regenerationHereditary Neurological Disorders
Cited by 119
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Interventional Influence of the Intestinal Microbiome Through Dietary Intervention and Bowel Cleansing Might Improve Motor Symptoms in Parkinson’s Disease
Hegelmaier, T., Lebbing, M., Duscha, A., Tomaske, L., Tönges, L., Holm, J. B., Bjørn Nielsen, H., Gatermann, S. G., Przuntek, H., & Haghikia, A. (2020) · Cells
Parkinson's Disease Mechanisms and TreatmentsGut microbiota and health
Cited by 118
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Modulation of Microglial Activity by Rho-Kinase (ROCK) Inhibition as Therapeutic Strategy in Parkinson’s Disease and Amyotrophic Lateral Sclerosis
Roser, A.-E., Tönges, L., & Lingor, P. (2017) · Frontiers in Aging Neuroscience
Neuroinflammation and Neurodegeneration MechanismsParkinson's Disease Mechanisms and Treatments
Cited by 77
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Emerging Immunotherapies for Parkinson Disease
Zella, S. M. A., Metzdorf, J., Ciftci, E., Ostendorf, F., Muhlack, S., Gold, R., & Tönges, L. (2019) · Neurology and Therapy
Parkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms
Cited by 64
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TGF-β 1 enhances neurite outgrowth via regulation of proteasome function and EFABP
Knöferle, J., Ramljak, S., Koch, J. C., Tönges, L., Asif, A. R., Michel, U., Wouters, F. S., Heermann, S., Krieglstein, K., Zerr, I., et al. (2010) · Neurobiology of Disease
Ubiquitin and proteasome pathwaysParkinson's Disease Mechanisms and Treatments
Cited by 50
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Rho Kinase Inhibition with Fasudil in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis—Symptomatic Treatment Potential after Disease Onset
Günther, R., Balck, A., Koch, J. C., Nientiedt, T., Sereda, M., Bähr, M., Lingor, P., & Tönges, L. (2017) · Frontiers in Pharmacology
Amyotrophic Lateral Sclerosis ResearchNeurogenetic and Muscular Disorders Research
Cited by 47
- Verified
Propionic acid and fasudil as treatment against rotenone toxicity in an in vitro model of Parkinson's disease
Ostendorf, F., Metzdorf, J., Gold, R., Haghikia, A., & Tönges, L. (2020) · Molecules
Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling
Cited by 46
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