Holmes, Megan C.

A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

Guy, J., Hendrich, B., Holmes, M., Martin, J. E., & Bird, A. (2001) · Nature Genetics

Genetics and Neurodevelopmental DisordersEpigenetics and DNA Methylation

Cited by 1,558

11β-hydroxysteroid dehydrogenases: Intracellular gate-keepers of tissue glucocorticoid action

Chapman, K., Holmes, M., & Seckl, J. (2013) · Physiological Reviews

Hormonal Regulation and HypertensionAdrenal Hormones and Disorders

Cited by 887

Mechanisms of Disease: glucocorticoids, their placental metabolism and fetal 'programming' of adult pathophysiology

Seckl, J. R., & Holmes, M. C. (2007) · Nature Clinical Practice Endocrinology & Metabolism

Birth, Development, and HealthStress Responses and Cortisol

Cited by 754

Novel Adipose Tissue–Mediated Resistance to Diet-Induced Visceral Obesity in 11β-Hydroxysteroid Dehydrogenase Type 1–Deficient Mice

Morton, N. M., Paterson, J. M., Masuzaki, H., Holmes, M. C., Staels, B., Fievet, C., Walker, B. R., Flier, J. S., Mullins, J. J., & Seckl, J. R. (2004) · Diabetes

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 512

11β-Hydroxysteroid dehydrogenases and the brain: From zero to hero, a decade of progress

Wyrwoll, C. S., Holmes, M. C., & Seckl, J. R. (2011) · Frontiers in Neuroendocrinology

Stress Responses and CortisolHormonal Regulation and Hypertension

Cited by 244

The Mother or the Fetus? 11β-Hydroxysteroid Dehydrogenase Type 2 Null Mice Provide Evidence for Direct Fetal Programming of Behavior by Endogenous Glucocorticoids

Holmes, M. C., Abrahamsen, C. T., French, K. L., Paterson, J. M., Mullins, J. J., & Seckl, J. R. (2006) · The Journal of Neuroscience

Birth, Development, and HealthStress Responses and Cortisol

Cited by 200

Altered Placental Function of 11β-Hydroxysteroid Dehydrogenase 2 Knockout Mice

Wyrwoll, C. S., Seckl, J. R., & Holmes, M. C. (2009) · Endocrinology

Birth, Development, and HealthPregnancy and preeclampsia studies

Cited by 169

Foetal and placental 11 β‐HSD 2: a hub for developmental programming

Cottrell, E. C., Seckl, J. R., Holmes, M. C., & Wyrwoll, C. S. (2014) · Acta Physiologica

Birth, Development, and HealthPregnancy and preeclampsia studies

Cited by 123

Reconciling the nutritional and glucocorticoid hypotheses of fetal programming

Cottrell, E. C., Holmes, M. C., Livingstone, D. E., Kenyon, C. J., & Seckl, J. R. (2012) · The FASEB Journal

Birth, Development, and HealthPregnancy and preeclampsia studies

Cited by 102

Maternal high-fat diet acts as a stressor increasing maternal glucocorticoids’ signaling to the fetus and disrupting maternal behavior and brain activation in C57BL/6J mice

Bellisario, V., Panetta, P., Balsevich, G., Baumann, V., Noble, J., Raggi, C., Nathan, O., Berry, A., Seckl, J., Schmidt, M., et al. (2015) · Psychoneuroendocrinology

Neuroendocrine regulation and behaviorBirth, Development, and Health

Cited by 88