Carette, Jan E.

Gene essentiality and synthetic lethality in haploid human cells

Blomen, V. A., Májek, P., Jae, L. T., Bigenzahn, J. W., Nieuwenhuis, J., Staring, J., Sacco, R., van Diemen, F. R., Olk, N., Stukalov, A., et al. (2015) · Science

Fungal and yeast genetics researchBioinformatics and Genomic Networks

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An essential receptor for adeno-associated virus infection

Pillay, S., Meyer, N. L., Puschnik, A. S., Davulcu, O., Diep, J., Ishikawa, Y., Jae, L. T., Wosen, J. E., Nagamine, C. M., Chapman, M. S., et al. (2016) · Nature

Virus-based gene therapy researchRNA Interference and Gene Delivery

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Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens

Marceau, C. D., Puschnik, A. S., Majzoub, K., Ooi, Y. S., Brewer, S. M., Fuchs, G., Swaminathan, K., Mata, M. A., Elias, J. E., Sarnow, P., et al. (2016) · Nature

Mosquito-borne diseases and controlViral Infectious Diseases and Gene Expression in Insects

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PLA2G16 represents a switch between entry and clearance of Picornaviridae

Staring, J., von Castelmur, E., Blomen, V. A., van den Hengel, L. G., Brockmann, M., Baggen, J., Thibaut, H. J., Nieuwenhuis, J., Janssen, H., van Kuppeveld, F. J. M., et al. (2017) · Nature

Viral Infections and Immunology Researchinterferon and immune responses

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MLKL Requires the Inositol Phosphate Code to Execute Necroptosis

Dovey, C. M., Diep, J., Clarke, B. P., Hale, A. T., McNamara, D. E., Guo, H., Brown, N. W., Cao, J. Y., Grace, C. R., Gough, P. J., et al. (2018) · Molecular Cell

Cell death mechanisms and regulationFerroptosis and cancer prognosis

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A CREB3–ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens

Reiling, J. H., Olive, A. J., Sanyal, S., Carette, J. E., Brummelkamp, T. R., Ploegh, H. L., Starnbach, M. N., & Sabatini, D. M. (2013) · Nature Cell Biology

Cellular transport and secretionEndoplasmic Reticulum Stress and Disease

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Complement pathway amplifies caspase-11–dependent cell death and endotoxin-induced sepsis severity

Napier, B. A., Brubaker, S. W., Sweeney, T. E., Monette, P., Rothmeier, G. H., Gertsvolf, N. A., Puschnik, A., Carette, J. E., Khatri, P., & Monack, D. M. (2016) · Journal of Experimental Medicine

Inflammasome and immune disordersImmune Response and Inflammation

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Human induced pluripotent stem cell–derived cardiomyocytes as an in vitro model for coxsackievirus B3–induced myocarditis and antiviral drug screening platform

Sharma, A., Marceau, C., Hamaguchi, R., Burridge, P. W., Rajarajan, K., Churko, J. M., Wu, H., Sallam, K. I., Matsa, E., Sturzu, A. C., et al. (2014) · Circulation Research

Viral Infections and Immunology ResearchPluripotent Stem Cells Research

Cited by 148

Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome

Tsvetkov, P., Mendillo, M. L., Zhao, J., Carette, J. E., Merrill, P. H., Cikes, D., Varadarajan, M., van Diemen, F. R., Penninger, J. M., Goldberg, A. L., et al. (2015) · eLife

Ubiquitin and proteasome pathwaysHeat shock proteins research

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Tissue Inhibitor of Metalloproteinase-3 Expression from an Oncolytic Adenovirus Inhibits Matrix Metalloproteinase Activity In vivo without Affecting Antitumor Efficacy in Malignant Glioma

Lamfers, M. L. M., Gianni, D., Tung, C.-H., Idema, S., Schagen, F. H. E., Carette, J. E., Quax, P. H. A., Van Beusechem, V. W., Vandertop, W. P., Dirven, C. M. F., et al. (2005) · Cancer Research

Virus-based gene therapy researchProtease and Inhibitor Mechanisms

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