Goel, Gautam

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

Tannahill, G. M., Curtis, A. M., Adamik, J., Palsson-McDermott, E. M., McGettrick, A. F., Goel, G., Frezza, C., Bernard, N. J., Kelly, B., Foley, N. H., et al. (2013) · Nature

Immune Response and InflammationImmune cells in cancer

Cited by 4,176

Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the Warburg effect in LPS-activated macrophages

Palsson-McDermott, E. M., Curtis, A. M., Goel, G., Lauterbach, M. A. R., Sheedy, F. J., Gleeson, L. E., van den Bosch, M. W. M., Quinn, S. R., Domingo-Fernandez, R., Johnston, D. G. W., et al. (2015) · Cell Metabolism

Immune cells in cancerCancer, Hypoxia, and Metabolism

Cited by 1,397

RNF166 determines recruitment of adaptor proteins during antibacterial autophagy

Heath, R. J., Goel, G., Baxt, L. A., Rush, J. S., Mohanan, V., Paulus, G. L. C., Jani, V., Lassen, K. G., & Xavier, R. J. (2016) · Cell Reports

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 108

Deep immune phenotyping reveals similarities between aging, Down syndrome, and autoimmunity

Lambert, K., Moo, K. G., Arnett, A., Goel, G., Hu, A., Flynn, K. J., Speake, C., Wiedeman, A. E., Gersuk, V. H., Linsley, P. S., et al. (2022) · Science Translational Medicine

Down syndrome and intellectual disability researchT-cell and B-cell Immunology

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