Kügler, Sebastian

Depletion of microglia and inhibition of exosome synthesis halt tau propagation

Asai, H., Ikezu, S., Tsunoda, S., Medalla, M., Luebke, J., Haydar, T., Wolozin, B., Butovsky, O., Kügler, S., & Ikezu, T. (2015) · Nature Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 1,591

A dual‐AAV approach restores fast exocytosis and partially rescues auditory function in deaf otoferlin knock‐out mice

Al‐Moyed, H., Cepeda, A. P., Jung, S., Moser, T., Kügler, S., & Reisinger, E. (2019) · EMBO Molecular Medicine

Hearing, Cochlea, Tinnitus, GeneticsVirus-based gene therapy research

Cited by 230

Reorganization of cortical population activity imaged throughout long-term sensory deprivation

Margolis, D. J., Lütcke, H., Schulz, K., Haiss, F., Weber, B., Kügler, S., Hasan, M. T., & Helmchen, F. (2012) · Nature Neuroscience

Tactile and Sensory InteractionsNeural dynamics and brain function

Cited by 203

Single-spike detection in vitro and in vivo with a genetic Ca2+ sensor

Wallace, D. J., zum Alten Borgloh, S. M., Astori, S., Yang, Y., Bausen, M., Kügler, S., Palmer, A. E., Tsien, R. Y., Sprengel, R., Kerr, J. N. D., et al. (2008) · Nature Methods

Advanced Fluorescence Microscopy TechniquesNeuroscience and Neuropharmacology Research

Cited by 191

Fractalkine activates NRF2/NFE2L2 and heme oxygenase 1 to restrain tauopathy-induced microgliosis

Lastres-Becker, I., Innamorato, N. G., Jaworski, T., Rábano, A., Kügler, S., Van Leuven, F., & Cuadrado, A. (2014) · Brain

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 160

β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration

Lodygin, D., Hermann, M., Schweingruber, N., Flügel-Koch, C., Watanabe, T., Schlosser, C., Merlini, A., Körner, H., Chang, H.-F., Fischer, H. J., et al. (2019) · Nature

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 140

Silencing and un-silencing of tetracycline-controlled genes in neurons

Zhu, P., Aller, M. I., Baron, U., Cambridge, S., Bausen, M., Herb, J., Sawinski, J., Cetin, A., Osten, P., Nelson, M. L., et al. (2007) · PLoS ONE

Bacterial Genetics and BiotechnologyGene Regulatory Network Analysis

Cited by 136

The X-linked inhibitor of apoptosis (XIAP) prevents cell death in axotomized CNS neurons in vivo

Kügler, S., Straten, G., Kreppel, F., Isenmann, S., Liston, P., & Bähr, M. (2000) · Cell Death & Differentiation

Cell death mechanisms and regulationNerve injury and regeneration

Cited by 84

CX3CR1-deficient microglia shows impaired signalling of the transcription factor NRF2: Implications in tauopathies

Castro-Sánchez, S., García-Yagüe, Á. J., Kügler, S., & Lastres-Becker, I. (2019) · Redox Biology

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 76

Identification of inhibitor‐of‐differentiation 2 (Id2) as a modulator of neuronal apoptosis

Gleichmann, M., Buchheim, G., El‐Bizri, H., Yokota, Y., Klockgether, T., Kügler, S., Bähr, M., Weller, M., & Schulz, J. B. (2002) · Journal of Neurochemistry

Cell death mechanisms and regulationNeurogenesis and neuroplasticity mechanisms

Cited by 35