Pearce, Margaret M.P.

Prion-like transmission of neuronal huntingtin aggregates to phagocytic glia in the Drosophila brain

Pearce, M. M. P., Spartz, E. J., Hong, W., Luo, L., & Kopito, R. R. (2015) · Nature Communications

Genetic Neurodegenerative DiseasesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 159

An Endoplasmic Reticulum (ER) Membrane Complex Composed of SPFH1 and SPFH2 Mediates the ER-associated Degradation of Inositol 1,4,5-Trisphosphate Receptors

Pearce, M. M. P., Wormer, D. B., Wilkens, S., & Wojcikiewicz, R. J. H. (2009) · Journal of Biological Chemistry

Endoplasmic Reticulum Stress and DiseaseUbiquitin and proteasome pathways

Cited by 114

SPFH2 Mediates the Endoplasmic Reticulum-associated Degradation of Inositol 1,4,5-Trisphosphate Receptors and Other Substrates in Mammalian Cells

Pearce, M. M. P., Wang, Y., Kelley, G. G., & Wojcikiewicz, R. J. H. (2007) · Journal of Biological Chemistry

Endoplasmic Reticulum Stress and DiseaseUbiquitin and proteasome pathways

Cited by 107

RNF170 Protein, an Endoplasmic Reticulum Membrane Ubiquitin Ligase, Mediates Inositol 1,4,5-Trisphosphate Receptor Ubiquitination and Degradation

Lu, J. P., Wang, Y., Sliter, D. A., Pearce, M. M. P., & Wojcikiewicz, R. J. H. (2011) · Journal of Biological Chemistry

Ubiquitin and proteasome pathwaysIon Channels and Receptors

Cited by 102

When worlds collide: IP3 receptors and the ERAD pathway

Wojcikiewicz, R. J. H., Pearce, M. M. P., Sliter, D. A., & Wang, Y. (2009) · Cell Calcium

Endoplasmic Reticulum Stress and DiseaseIon Channels and Receptors

Cited by 54

SPFH1 and SPFH2 mediate the ubiquitination and degradation of inositol 1,4,5-trisphosphate receptors in muscarinic receptor-expressing HeLa cells

Wang, Y., Pearce, M. M. P., Sliter, D. A., Olzmann, J. A., Christianson, J. C., Kopito, R. R., Boeckmann, S., Gagen, C., Leichner, G. S., Roitelman, J., et al. (2009) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Ubiquitin and proteasome pathwaysEndoplasmic Reticulum Stress and Disease

Cited by 33