Ordureau, Alban

The BioPlex network: a systematic exploration of the human interactome

Huttlin, E. L., Ting, L., Bruckner, R. J., Gebreab, F., Gygi, M. P., Szpyt, J., Tam, S., Zarraga, G., Colby, G., Baltier, K., et al. (2015) · Cell

Bioinformatics and Genomic NetworksAdvanced Proteomics Techniques and Applications

Cited by 1,425

Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways

Cirulli, E. T., Lasseigne, B. N., Petrovski, S., Sapp, P. C., Dion, P. A., Leblond, C. S., Couthouis, J., Lu, Y.-F., Wang, Q., Krueger, B. J., et al. (2015) · Science

Amyotrophic Lateral Sclerosis ResearchHereditary Neurological Disorders

Cited by 966

The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy

Heo, J.-M., Ordureau, A., Paulo, J. A., Rinehart, J., & Harper, J. W. (2015) · Molecular Cell

Autophagy in Disease and TherapyParkinson's Disease Mechanisms and Treatments

Cited by 906

Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress

Pickrell, A. M., Huang, C.-H., Kennedy, S. R., Ordureau, A., Sideris, D. P., Hoekstra, J. G., Harper, J. W., & Youle, R. J. (2015) · Neuron

Parkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and Therapy

Cited by 327

Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy

Ordureau, A., Heo, J.-M., Duda, D. M., Paulo, J. A., Olszewski, J. L., Yanishevski, D., Rinehart, J., Schulman, B. A., & Harper, J. W. (2015) · Proceedings of the National Academy of Sciences

Parkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and Therapy

Cited by 310

RAB7A phosphorylation by TBK1 promotes mitophagy via the PINK-PARKIN pathway

Heo, J.-M., Ordureau, A., Swarup, S., Paulo, J. A., Shen, K., Sabatini, D. M., & Harper, J. W. (2018) · Science Advances

Autophagy in Disease and TherapyParkinson's Disease Mechanisms and Treatments

Cited by 199

System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes

Zhang, W., Wu, K.-P., Sartori, M. A., Kamadurai, H. B., Ordureau, A., Jiang, C., Mercredi, P. Y., Murchie, R., Hu, J., Persaud, A., et al. (2016) · Molecular Cell

Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors

Cited by 168

Substitution of PINK1 Gly411 modulates substrate receptivity and turnover

Fiesel, F. C., Fričová, D., Hayes, C. S., Coban, M. A., Hudec, R., Bredenberg, J. M., Broadway, B. J., Markham, B. N., Yan, T., Boneski, P. K., et al. (2023) · Autophagy

Parkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and Therapy

Cited by 29