Croucher, David R.

CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan

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MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer

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MASTL overexpression promotes chromosome instability and metastasis in breast cancer

Rogers, S., McCloy, R. A., Parker, B. L., Gallego-Ortega, D., Law, A. M. K., Chin, V. T., Conway, J. R. W., Fey, D., Millar, E. K. A., O’Toole, S., et al. (2018) · Oncogene

Microtubule and mitosis dynamicsCancer-related Molecular Pathways

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Activation of CAMK2 by pseudokinase PEAK1 represents a targetable pathway in triple negative breast cancer

Yang, X., Ma, X., Zhao, T., Croucher, D. R., Nguyen, E. V., Clark, K. C., Hu, C., Latham, S. L., Bayly-Jones, C., Nguyen, B. V., et al. (2025) · Nature Communications

Protein Kinase Regulation and GTPase SignalingCancer Mechanisms and Therapy

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Feed-forward stimulation of CAMK2 by the oncogenic pseudokinase PEAK1 generates a therapeutically ‘actionable’ signalling axis in triple negative breast cancer

Yang, X., Ma, X., Zhao, T., Croucher, D. R., Nguyen, E. V., Clark, K. C., Hu, C., Latham, S. L., Bayly-Jones, C., Nguyen, V. C. B., et al. (2024) · Nature Communications

Protein Kinase Regulation and GTPase SignalingCancer Mechanisms and Therapy

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