Kormann, Michael S.D.

Expression of therapeutic proteins after delivery of chemically modified mRNA in mice

Kormann, M. S. D., Hasenpusch, G., Aneja, M. K., Nica, G., Flemmer, A. W., Herber-Jonat, S., Huppmann, M., Mays, L. E., Illenyi, M., Schams, A., et al. (2011) · Nature Biotechnology

RNA Interference and Gene DeliveryRNA and protein synthesis mechanisms

Cited by 733

Uridine Depletion and Chemical Modification Increase Cas9 mRNA Activity and Reduce Immunogenicity without HPLC Purification

Vaidyanathan, S., Azizian, K. T., Haque, A. K. M. A., Henderson, J. M., Hendel, A., Shore, S., Antony, J. S., Hogrefe, R. I., Kormann, M. S. D., Porteus, M. H., et al. (2018) · Molecular Therapy Nucleic Acids

CRISPR and Genetic EngineeringRNA Interference and Gene Delivery

Cited by 262

In vivo genome editing using nuclease-encoding mRNA corrects SP-B deficiency

Mahiny, A. J., Dewerth, A., Mays, L. E., Alkhaled, M., Mothes, B., Malaeksefat, E., Loretz, B., Rottenberger, J., Brosch, D. M., Reautschnig, P., et al. (2015) · Nature Biotechnology

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 139

Modified Foxp3 mRNA protects against asthma through an IL-10-dependent mechanism

Mays, L. E., Ammon-Treiber, S., Mothes, B., Alkhaled, M., Rottenberger, J., Müller-Hermelink, E. S., Grimm, M., Mezger, M., Beer-Hammer, S., von Stebut, E., et al. (2013) · Journal of Clinical Investigation

Asthma and respiratory diseasesAllergic Rhinitis and Sensitization

Cited by 113

Recent Developments in mRNA-Based Protein Supplementation Therapy to Target Lung Diseases

Sahu, I., Haque, A. K. M. A., Weidensee, B., Weinmann, P., & Kormann, M. S. D. (2019) · Molecular Therapy

RNA Interference and Gene DeliveryInhalation and Respiratory Drug Delivery

Cited by 104

Chemically modified hCFTR mRNAs recuperate lung function in a mouse model of cystic fibrosis

Haque, A. K. M. A., Dewerth, A., Antony, J. S., Riethmüller, J., Schweizer, G. R., Weinmann, P., Latifi, N., Yasar, H., Pedemonte, N., Sondo, E., et al. (2018) · Scientific Reports

RNA Interference and Gene DeliveryCystic Fibrosis Research Advances

Cited by 80

Rare TLR2 mutations reduce TLR2 receptor function and can increase atopy risk

Kormann, M. S. D., Ferstl, R., Depner, M., Klopp, N., Spiller, S., Illig, T., Vogelberg, C., Von Mutius, E., Kirschning, C. J., & Kabesch, M. (2009) · Allergy

Immune Response and InflammationDermatology and Skin Diseases

Cited by 39