Downar, Jonathan

Resting-state connectivity biomarkers define neurophysiological subtypes of depression

Drysdale, A. T., Grosenick, L., Downar, J., Dunlop, K., Mansouri, F., Meng, Y., Fetcho, R. N., Zebley, B., Oathes, D. J., Etkin, A., et al. (2017) · Nature Medicine

Functional Brain Connectivity StudiesTreatment of Major Depression

Cited by 2,170

Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): a randomised non-inferiority trial

Blumberger, D. M., Vila-Rodriguez, F., Thorpe, K. E., Feffer, K., Noda, Y., Giacobbe, P., Knyahnytska, Y., Kennedy, S. H., Lam, R. W., Daskalakis, Z. J., et al. (2018) · The Lancet

Transcranial Magnetic Stimulation StudiesTreatment of Major Depression

Cited by 1,363

A multimodal cortical network for the detection of changes in the sensory environment

Downar, J., Crawley, A. P., Mikulis, D. J., & Davis, K. D. (2000) · Nature Neuroscience

Multisensory perception and integrationSpatial Neglect and Hemispheric Dysfunction

Cited by 947

Cortico-striatal-thalamic loop circuits of the salience network: A central pathway in psychiatric disease and treatment

Peters, S. K., Dunlop, K., & Downar, J. (2016) · Frontiers in Systems Neuroscience

Neural and Behavioral Psychology StudiesDeep Brain Stimulation and Movement Disorders

Cited by 611

Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder: Section 4. Neurostimulation Treatments

Milev, R. V., Giacobbe, P., Kennedy, S. H., Blumberger, D. M., Daskalakis, Z. J., Downar, J., Modirrousta, M., Patry, S., Vila-Rodriguez, F., Lam, R. W., et al. (2016) · The Canadian Journal of Psychiatry

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 586

A cortical network sensitive to stimulus salience in a neutral behavioral context across multiple sensory modalities.

Downar, J., Crawley, A. P., Mikulis, D. J., & Davis, K. D. (2002) · Journal of Neurophysiology

Neural and Behavioral Psychology StudiesVisual Attention and Saliency Detection

Cited by 544

Using brain imaging to improve spatial targeting of transcranial magnetic stimulation for depression

Cash, R. F. H., Weigand, A., Zalesky, A., Siddiqi, S. H., Downar, J., Fitzgerald, P. B., & Fox, M. D. (2021) · Biological Psychiatry

Transcranial Magnetic Stimulation StudiesTreatment of Major Depression

Cited by 366

rTMS of the dorsomedial prefrontal cortex for major depression: Safety, tolerability, effectiveness, and outcome predictors for 10 Hz versus intermittent theta-burst stimulation

Bakker, N., Shahab, S., Giacobbe, P., Blumberger, D. M., Daskalakis, Z. J., Kennedy, S. H., & Downar, J. (2015) · Brain Stimulation

Transcranial Magnetic Stimulation StudiesTreatment of Major Depression

Cited by 306

Resting-state cortico-thalamic-striatal connectivity predicts response to dorsomedial prefrontal rTMS in major depressive disorder

Salomons, T. V., Dunlop, K., Kennedy, S. H., Flint, A., Geraci, J., Giacobbe, P., & Downar, J. (2014) · Neuropsychopharmacology

Transcranial Magnetic Stimulation StudiesFunctional Brain Connectivity Studies

Cited by 299

Cortico-Striatal-Thalamic Loop Circuits of the Orbitofrontal Cortex: Promising Therapeutic Targets in Psychiatric Illness

Fettes, P., Schulze, L., & Downar, J. (2017) · Frontiers in Systems Neuroscience

Neural and Behavioral Psychology StudiesDeep Brain Stimulation and Movement Disorders

Cited by 299

Concordance between BeamF3 and MRI-neuronavigated target sites for repetitive transcranial magnetic stimulation of the left dorsolateral prefrontal cortex

Mir-Moghtadaei, A., Caballero, R., Fried, P., Fox, M. D., Lee, K., Giacobbe, P., Daskalakis, Z. J., Blumberger, D. M., & Downar, J. (2015) · Brain Stimulation

Transcranial Magnetic Stimulation StudiesDeep Brain Stimulation and Movement Disorders

Cited by 269

New targets for rTMS in depression: A review of convergent evidence

Downar, J., & Daskalakis, Z. J. (2013) · Brain Stimulation

Transcranial Magnetic Stimulation StudiesTreatment of Major Depression

Cited by 257

Efficacy, tolerability, and cognitive effects of deep transcranial magnetic stimulation for late-life depression: a prospective randomized controlled trial

Kaster, T. S., Daskalakis, Z. J., Noda, Y., Knyahnytska, Y., Downar, J., Rajji, T. K., Levkovitz, Y., Zangen, A., Butters, M. A., Mulsant, B. H., et al. (2018) · Neuropsychopharmacology

Transcranial Magnetic Stimulation StudiesElectroconvulsive Therapy Studies

Cited by 174

Noninvasive brain stimulation treatments for addiction and major depression

Dunlop, K., Hanlon, C. A., & Downar, J. (2017) · Annals of the New York Academy of Sciences

Transcranial Magnetic Stimulation StudiesTreatment of Major Depression

Cited by 171

The neural crossroads of psychiatric illness: an emerging target for brain stimulation

Downar, J., Blumberger, D. M., & Daskalakis, Z. J. (2016) · Trends in Cognitive Sciences

Transcranial Magnetic Stimulation StudiesDeep Brain Stimulation and Movement Disorders

Cited by 166

Reductions in cortico-striatal hyperconnectivity accompany successful treatment of obsessive-compulsive disorder with dorsomedial prefrontal rTMS

Dunlop, K., Woodside, B., Olmsted, M., Colton, P., Giacobbe, P., & Downar, J. (2016) · Neuropsychopharmacology

Obsessive-Compulsive Spectrum DisordersTranscranial Magnetic Stimulation Studies

Cited by 147

Effectiveness of Standard Sequential Bilateral Repetitive Transcranial Magnetic Stimulation vs Bilateral Theta Burst Stimulation in Older Adults With Depression

Blumberger, D. M., Mulsant, B. H., Thorpe, K. E., McClintock, S. M., Konstantinou, G. N., Lee, H. H., Nestor, S. M., Noda, Y., Rajji, T. K., Trevizol, A. P., et al. (2022) · JAMA Psychiatry

Transcranial Magnetic Stimulation StudiesTreatment of Major Depression

Cited by 142

1 Hz rTMS of the right orbitofrontal cortex for major depression: Safety, tolerability and clinical outcomes

Feffer, K., Fettes, P., Giacobbe, P., Daskalakis, Z. J., Blumberger, D. M., & Downar, J. (2018) · European Neuropsychopharmacology

Transcranial Magnetic Stimulation StudiesTreatment of Major Depression

Cited by 116

Unilateral and bilateral MRI-targeted repetitive transcranial magnetic stimulation for treatment-resistant depression: a randomized controlled study

Blumberger, D. M., Maller, J. J., Thomson, L., Mulsant, B. H., Rajji, T. K., Maher, M., Brown, P. E., Downar, J., Vila-Rodriguez, F., Fitzgerald, P. B., et al. (2016) · Journal of Psychiatry and Neuroscience

Transcranial Magnetic Stimulation StudiesTreatment of Major Depression

Cited by 106

Magnetic seizure therapy (MST) for major depressive disorder

Daskalakis, Z. J., Dimitrova, J., McClintock, S. M., Sun, Y., Voineskos, D., Rajji, T. K., Goldbloom, D. S., Wong, A. H. C., Knyahnytska, Y., Mulsant, B. H., et al. (2020) · Neuropsychopharmacology

Electroconvulsive Therapy StudiesTranscranial Magnetic Stimulation Studies

Cited by 92

Magnetic seizure therapy reduces suicidal ideation and produces neuroplasticity in treatment-resistant depression

Sun, Y., Blumberger, D. M., Mulsant, B. H., Rajji, T. K., Fitzgerald, P. B., Barr, M. S., Downar, J., Wong, W., Farzan, F., & Daskalakis, Z. J. (2018) · Translational Psychiatry

Transcranial Magnetic Stimulation StudiesElectroconvulsive Therapy Studies

Cited by 85

A randomized sham controlled comparison of once vs twice-daily intermittent theta burst stimulation in depression: A Canadian rTMS treatment and biomarker network in depression (CARTBIND) study

Blumberger, D. M., Vila-Rodriguez, F., Wang, W., Knyahnytska, Y., Butterfield, M., Noda, Y., Yariv, S., Isserles, M., Voineskos, D., Ainsworth, N. J., et al. (2021) · Brain Stimulation

Transcranial Magnetic Stimulation StudiesElectroconvulsive Therapy Studies

Cited by 81

Predictors of remission after repetitive transcranial magnetic stimulation for the treatment of major depressive disorder: an analysis from the randomised non-inferiority THREE-D trial

Trevizol, A. P., Downar, J., Vila-Rodriguez, F., Thorpe, K. E., Daskalakis, Z. J., & Blumberger, D. M. (2020) · EClinicalMedicine

Transcranial Magnetic Stimulation StudiesTreatment of Major Depression

Cited by 70

Unilateral and bilateral repetitive transcranial magnetic stimulation for treatment-resistant late-life depression

Trevizol, A. P., Goldberger, K. W., Mulsant, B. H., Rajji, T. K., Downar, J., Daskalakis, Z. J., & Blumberger, D. M. (2019) · International Journal of Geriatric Psychiatry

Transcranial Magnetic Stimulation StudiesTreatment of Major Depression

Cited by 70