Becker, Kevin G.

Resveratrol improves health and survival of mice on a high-calorie diet

Baur, J. A., Pearson, K. J., Price, N. L., Jamieson, H. A., Lerin, C., Kalra, A., Prabhu, V. V., Allard, J. S., Lopez-Lluch, G., Lewis, K., et al. (2006) · Nature

Sirtuins and Resveratrol in MedicineGenetics, Aging, and Longevity in Model Organisms

Cited by 4,290

Metformin improves healthspan and lifespan in mice

Martin-Montalvo, A., Mercken, E. M., Mitchell, S. J., Palacios, H. H., Mote, P. L., Scheibye-Knudsen, M., Gomes, A. P., Ward, T. M., Minor, R. K., Blouin, M.-J., et al. (2013) · Nature Communications

Genetics, Aging, and Longevity in Model OrganismsMetabolism, Diabetes, and Cancer

Cited by 1,445

Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span

Pearson, K. J., Baur, J. A., Lewis, K. N., Peshkin, L., Price, N. L., Labinskyy, N., Swindell, W. R., Kamara, D., Minor, R. K., Perez, E., et al. (2008) · Cell Metabolism

Sirtuins and Resveratrol in MedicineGenetics, Aging, and Longevity in Model Organisms

Cited by 1,162

RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr1 null mice

Miyashiro, K. Y., Beckel-Mitchener, A., Purk, T. P., Becker, K. G., Barret, T., Liu, L., Carbonetto, S., Weiler, I. J., Greenough, W. T., & Eberwine, J. (2003) · Neuron

Genetics and Neurodevelopmental DisordersRNA Research and Splicing

Cited by 495

Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice

Mitchell, S. J., Madrigal-Matute, J., Scheibye-Knudsen, M., Fang, E., Aon, M., González-Reyes, J. A., Cortassa, S., Kaushik, S., Gonzalez-Freire, M., Patel, B., et al. (2016) · Cell Metabolism

Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine

Cited by 451

AGEMAP: A Gene Expression Database for Aging in Mice

Zahn, J. M., Poosala, S., Owen, A. B., Ingram, D. K., Lustig, A., Carter, A., Weeraratna, A. T., Taub, D. D., Gorospe, M., Mazan-Mamczarz, K., et al. (2007) · PLoS Genetics

Genetics, Aging, and Longevity in Model OrganismsSingle-cell and spatial transcriptomics

Cited by 431

RETRACTED ARTICLE: sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance

Kaur, A., Webster, M. R., Marchbank, K., Behera, R., Ndoye, A., Kugel, C. H., Dang, V. M., Appleton, J., O’Connell, M. P., Cheng, P., et al. (2016) · Nature

Melanoma and MAPK PathwaysWnt/β-catenin signaling in development and cancer

Cited by 398

Transcriptional profiling of aging in human muscle reveals a common aging signature

Zahn, J. M., Sonu, R., Vogel, H., Crane, E., Mazan-Mamczarz, K., Rabkin, R., Davis, R. W., Becker, K. G., Owen, A. B., & Kim, S. K. (2006) · PLoS Genetics

Genetics, Aging, and Longevity in Model OrganismsMuscle Physiology and Disorders

Cited by 351

Age-related changes in microRNA levels in serum

Hooten, N. N., Fitzpatrick, M., Wood, W. H., De, S., Ejiogu, N., Zhang, Y., Mattison, J. A., Becker, K. G., Zonderman, A. B., & Evans, M. K. (2013) · Aging

MicroRNA in disease regulationTelomeres, Telomerase, and Senescence

Cited by 329

Calorie restriction in humans inhibits the PI 3 K/AKT pathway and induces a younger transcription profile

Mercken, E. M., Crosby, S. D., Lamming, D. W., JeBailey, L., Krzysik‐Walker, S., Villareal, D. T., Capri, M., Franceschi, C., Zhang, Y., Becker, K., et al. (2013) · Aging Cell

Genetics, Aging, and Longevity in Model OrganismsMuscle Physiology and Disorders

Cited by 261

Evidence for miR‐181 involvement in neuroinflammatory responses of astrocytes

Hutchison, E. R., Kawamoto, E. M., Taub, D. D., Lal, A., Abdelmohsen, K., Zhang, Y., Wood, W. H., Lehrmann, E., Camandola, S., Becker, K. G., et al. (2013) · Glia

Neuroinflammation and Neurodegeneration MechanismsMicroRNA in disease regulation

Cited by 246

Sex-dependent metabolic, neuroendocrine, and cognitive responses to dietary energy restriction and excess

Martin, B., Pearson, M., Kebejian, L., Golden, E., Keselman, A., Bender, M., Carlson, O., Egan, J., Ladenheim, B., Cadet, J.-L., et al. (2007) · Endocrinology

Regulation of Appetite and ObesityDietary Effects on Health

Cited by 199

Metformin‐mediated increase in DICER1 regulates microRNA expression and cellular senescence

Noren Hooten, N., Martin‐Montalvo, A., Dluzen, D. F., Zhang, Y., Bernier, M., Zonderman, A. B., Becker, K. G., Gorospe, M., Cabo, R., & Evans, M. K. (2016) · Aging Cell

Metabolism, Diabetes, and CancerTelomeres, Telomerase, and Senescence

Cited by 196

Tomatidine Enhances Lifespan and Healthspan in C. elegans through Mitophagy Induction Via the SKN-1/Nrf2 Pathway

Fang, E. F., Waltz, T. B., Kassahun, H., Lu, Q., Kerr, J. S., Morevati, M., Fivenson, E. M., Wollman, B. N., Marosi, K., Wilson, M. A., et al. (2017) · Scientific Reports

Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and Therapy

Cited by 187

Control of gene expression during T cell activation: alternate regulation of mRNA transcription and mRNA stability

Cheadle, C., Fan, J., Cho-Chung, Y. S., Werner, T., Ray, J., Do, L., Gorospe, M., & Becker, K. G. (2005) · BMC Genomics

RNA Research and SplicingGene expression and cancer classification

Cited by 183

Commensal bacteria contribute to insulin resistance in aging by activating innate B1a cells

Bodogai, M., O’Connell, J., Kim, K., Kim, Y., Moritoh, K., Chen, C., Gusev, F., Vaughan, K., Shulzhenko, N., Mattison, J. A., et al. (2018) · Science Translational Medicine

Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases

Cited by 182

Disulfiram Treatment Normalizes Body Weight in Obese Mice

Bernier, M., Mitchell, S. J., Wahl, D., Diaz, A., Singh, A., Seo, W., Wang, M., Ali, A., Kaiser, T., Price, N. L., et al. (2020) · Cell Metabolism

Regulation of Appetite and ObesityPharmacology and Obesity Treatment

Cited by 85

Role of heparin binding growth factors in nigrostriatal dopamine system development and Parkinson's disease

Marchionini, D. M., Lehrmann, E., Chu, Y., He, B., Sortwell, C. E., Becker, K. G., Freed, W. J., Kordower, J. H., & Collier, T. J. (2007) · Brain Research

Parkinson's Disease Mechanisms and TreatmentsNerve injury and regeneration

Cited by 69

The mitochondrial uncoupler DNP triggers brain cell mTOR signaling network reprogramming and CREB pathway up‐regulation

Liu, D., Zhang, Y., Gharavi, R., Park, H. R., Lee, J., Siddiqui, S., Telljohann, R., Nassar, M. R., Cutler, R. G., Becker, K. G., et al. (2015) · Journal of Neurochemistry

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 68

Environmental enrichment during adolescence regulates gene expression in the striatum of mice

Thiriet, N., Amar, L., Toussay, X., Lardeux, V., Ladenheim, B., Becker, K. G., Cadet, J. L., Solinas, M., & Jaber, M. (2008) · Brain Research

Neurotransmitter Receptor Influence on BehaviorNeurogenesis and neuroplasticity mechanisms

Cited by 51

Age-associated alterations in inducible gene transcription in human CD4+ T lymphocytes

Bektas, A., Zhang, Y., Wood, W. H., Becker, K. G., Madara, K., Ferrucci, L., & Sen, R. (2013) · Aging

T-cell and B-cell ImmunologyNF-κB Signaling Pathways

Cited by 31