Guy, R. Kiplin

A surface on the androgen receptor that allosterically regulates coactivator binding

Estébanez-Perpiñá, E., Arnold, L. A., Nguyen, P., Rodrigues, E. D., Mar, E., Bateman, R., Pallai, P., Shokat, K. M., Baxter, J. D., Guy, R. K., et al. (2007) · Proceedings of the National Academy of Sciences

Prostate Cancer Treatment and ResearchEstrogen and related hormone effects

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Identification and Characterization of the First Small Molecule Inhibitor of MDMX

Reed, D., Shen, Y., Shelat, A. A., Arnold, L. A., Ferreira, A. M., Zhu, F., Mills, N., Smithson, D. C., Regni, C. A., Bashford, D., et al. (2010) · Journal of Biological Chemistry

Cancer-related Molecular PathwaysHeat shock proteins research

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NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells

Paugh, S. W., Bonten, E. J., Savic, D., Ramsey, L. B., Thierfelder, W. E., Gurung, P., Malireddi, R. K. S., Actis, M., Mayasundari, A., Min, J., et al. (2015) · Nature Genetics

Acute Lymphoblastic Leukemia researchInflammasome and immune disorders

Cited by 164

Targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKBP52 in prostate cancer cells

De Leon, J. T., Iwai, A., Feau, C., Garcia, Y., Balsiger, H. A., Storer, C. L., Suro, R. M., Garza, K. M., Lee, S., Sang Kim, Y., et al. (2011) · Proceedings of the National Academy of Sciences

Prostate Cancer Treatment and ResearchHeat shock proteins research

Cited by 132

Novel Selective Inhibitors of the Interaction of Individual Nuclear Hormone Receptors with a Mutually Shared Steroid Receptor Coactivator 2

Geistlinger, T. R., & Guy, R. K. (2003) · Journal of the American Chemical Society

Estrogen and related hormone effectsChemical Synthesis and Analysis

Cited by 94

Whole-body physiologically based pharmacokinetic model for nutlin-3a in mice after intravenous and oral administration

Zhang, F., Tagen, M., Throm, S., Mallari, J., Miller, L., Guy, R. K., Dyer, M. A., Williams, R. T., Roussel, M. F., Nemeth, K., et al. (2011) · Drug Metabolism and Disposition

Pharmaceutical studies and practicesPharmacogenetics and Drug Metabolism

Cited by 67

On the Mechanism of Action of SJ-172550 in Inhibiting the Interaction of MDM4 and p53

Bista, M., Smithson, D., Pecak, A., Salinas, G., Pustelny, K., Min, J., Pirog, A., Finch, K., Zdzalik, M., Waddell, B., et al. (2012) · PLoS ONE

Cancer-related Molecular PathwaysHeat shock proteins research

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