Hayward, Nicholas K.

POT1 loss-of-function variants predispose to familial melanoma

Robles-Espinoza, C. D., Harland, M., Ramsay, A. J., Aoude, L. G., Quesada, V., Ding, Z., Pooley, K. A., Pritchard, A. L., Tiffen, J. C., Petljak, M., et al. (2014) · Nature Genetics

Telomeres, Telomerase, and SenescenceCutaneous Melanoma Detection and Management

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A Single SNP in an Evolutionary Conserved Region within Intron 86 of the HERC2 Gene Determines Human Blue-Brown Eye Color

Sturm, R. A., Duffy, D. L., Zhao, Z. Z., Leite, F. P. N., Stark, M. S., Hayward, N. K., Martin, N. G., & Montgomery, G. W. (2008) · The American Journal of Human Genetics

melanin and skin pigmentationGenetic Associations and Epidemiology

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Increased MAPK reactivation in early resistance to dabrafenib/trametinib combination therapy of BRAF-mutant metastatic melanoma

Long, G. V., Fung, C., Menzies, A. M., Pupo, G. M., Carlino, M. S., Hyman, J., Shahheydari, H., Tembe, V., Thompson, J. F., Saw, R. P., et al. (2014) · Nature Communications

Melanoma and MAPK PathwaysLung Cancer Treatments and Mutations

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The CDKN2A (p16) Gene and Human Cancer

Foulkes, W. D., Flanders, T. Y., Pollock, P. M., & Hayward, N. K. (1997) · Molecular Medicine

Cancer-related Molecular PathwaysCutaneous Melanoma Detection and Management

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Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer

Akdemir, K. C., Le, V. T., Chandran, S., Li, Y., Verhaak, R. G., Beroukhim, R., Campbell, P. J., Chin, L., Dixon, J. R., Futreal, P. A., et al. (2020) · Nature Genetics

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

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Transcriptional Pathway Signatures Predict MEK Addiction and Response to Selumetinib (AZD6244)

Dry, J. R., Pavey, S., Pratilas, C. A., Harbron, C., Runswick, S., Hodgson, D., Chresta, C., McCormack, R., Byrne, N., Cockerill, M., et al. (2010) · Cancer Research

Melanoma and MAPK PathwaysProtein Kinase Regulation and GTPase Signaling

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A three-single-nucleotide polymorphism haplotype in intron 1 of OCA2 explains most human eye-color variation

Duffy, D. L., Montgomery, G. W., Chen, W., Zhao, Z. Z., Le, L., James, M. R., Hayward, N. K., Martin, N. G., & Sturm, R. A. (2007) · The American Journal of Human Genetics

melanin and skin pigmentationGenetic Associations and Epidemiology

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Whole genome landscapes of uveal melanoma show an ultraviolet radiation signature in iris tumours

Johansson, P. A., Brooks, K., Newell, F., Palmer, J. M., Wilmott, J. S., Pritchard, A. L., Broit, N., Wood, S., Carlino, M. S., Leonard, C., et al. (2020) · Nature Communications

Ocular Oncology and TreatmentsCancer Genomics and Diagnostics

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MC1R Is a Potent Regulator of PTEN after UV Exposure in Melanocytes

Cao, J., Wan, L., Hacker, E., Dai, X., Lenna, S., Jimenez-Cervantes, C., Wang, Y., Leslie, N. R., Xu, G. X., Widlund, H. R., et al. (2013) · Molecular Cell

Melanoma and MAPK Pathwaysmelanin and skin pigmentation

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Melanocortin 1 receptor and risk of cutaneous melanoma: A meta‐analysis and estimates of population burden

Williams, P. F., Olsen, C. M., Hayward, N. K., & Whiteman, D. C. (2011) · International Journal of Cancer

melanin and skin pigmentationCutaneous Melanoma Detection and Management

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Recurrent inactivating RASA2 mutations in melanoma

Arafeh, R., Qutob, N., Emmanuel, R., Keren-Paz, A., Madore, J., Elkahloun, A., Wilmott, J. S., Gartner, J. J., Di Pizio, A., Winograd-Katz, S., et al. (2015) · Nature Genetics

Melanoma and MAPK PathwaysProtein Kinase Regulation and GTPase Signaling

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Medical and Surgical Care of Patients with Mesothelioma and Their Relatives Carrying Germline BAP1 Mutations

Carbone, M., Pass, H. I., Ak, G., Alexander, H. R., Baas, P., Baumann, F., Blakely, A. M., Bueno, R., Bzura, A., Cardillo, G., et al. (2022) · Journal of Thoracic Oncology

Occupational and environmental lung diseasesBRCA gene mutations in cancer

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