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CAPN1 is a novel binding partner and regulator of the tumor suppressor NF1 in melanoma

Alon, M., Arafeh, R., Lee, J. S., Madan, S., Kalaora, S., Nagler, A., Abgarian, T., Greenberg, P., Ruppin, E., & Samuels, Y. (2018) · Oncotarget · doi:10.18632/oncotarget.25805 · Cited by 15 · see citing works

Identification of Potential Genes and Critical Pathways in Postoperative Recurrence of Crohn’s Disease by Machine Learning And WGCNA Network Analysis

Rajalingam, A., Sekar, K., & Ganjiwale, A. D. (2023) · Current Genomics · doi:10.2174/1389202924666230601122334 · Cited by 14 · see citing works

Genomic and Transcriptomic Underpinnings of Melanoma Genesis, Progression, and Metastasis

Cherepakhin, O. S., Argényi, Z. B., & Moshiri, A. S. (2021) · Cancers · doi:10.3390/cancers14010123 · Cited by 14 · see citing works

Molecular Profile of Skin Cancer

Porumb‐Andrese, E., Scutariu, M. M., Luchian, I. A., Schreiner, T. G., Mârţu, I., Porumb, V., Popa, C. G., Sandu, D., & Ursu, R. G. (2021) · Applied Sciences · doi:10.3390/app11199142 · Cited by 13 · see citing works

Two GEO MicroRNA Expression Profile Based High-Throughput Screen to Identify MicroRNA-31-3p Regulating Growth of Medullary Thyroid Carcinoma Cell by Targeting RASA2

Jiang, M., Shi, X., Zhu, H., Wu, W. D., & Li, J. (2019) · Medical Science Monitor · doi:10.12659/msm.916815 · Cited by 12 · see citing works

RASA4 inhibits the HIFα signaling pathway to suppress proliferation of cervical cancer cells

Chen, J., Huang, J., Huang, Q., Li, J., Chen, E., & Xu, W. (2021) · Bioengineered · doi:10.1080/21655979.2021.2002499 · Cited by 12 · see citing works

Gene editing: Towards the third generation of adoptive T-cell transfer therapies

Puig-Saus, C., & Ribas, A. (2019) · Immuno-Oncology Technology · doi:10.1016/j.iotech.2019.06.001 · Cited by 11 · see citing works

A Melanoma-Tailored Next-Generation Sequencing Panel Coupled with a Comprehensive Analysis to Improve Routine Melanoma Genotyping

Louveau, B., Jouenne, F., Tétu, P., Sadoux, A., Gruber, A., Lopes, E., Delyon, J., Serror, K., Marco, O., Meda, L. D., et al. (2020) · Targeted Oncology · doi:10.1007/s11523-020-00764-4 · Cited by 10 · see citing works

Targeted DNA Sequencing of Cutaneous Melanoma Identifies Prognostic and Predictive Alterations

Haugh, A. M., Osorio, R. C., Francois, R. A., Tawil, M. E., Tsai, K. K., Tetzlaff, M. T., DAUD, A. I., & Vasudevan, H. N. (2024) · Cancers · doi:10.3390/cancers16071347 · Cited by 9 · see citing works

EGR3 Inhibits Tumor Progression by Inducing Schwann Cell‐Like Differentiation

Chen, C., Chen, Y., Li, Y., Zhang, H., Huang, X., Li, Y., Li, Z., Han, J., Wu, X., Liu, H., et al. (2024) · Advanced Science · doi:10.1002/advs.202400066 · Cited by 8 · see citing works

The Dynamics of ERK Signaling in Melanoma, and the Response to BRAF or MEK Inhibition, Are Cell Cycle DependentPreprint

Simpson, C., Ferrari, N., Calvo, F., & Bakal, C. (2018) · SSRN Electronic Journal · doi:10.2139/ssrn.3188455 · Cited by 9 · see citing works

HGVA: the Human Genome Variation Archive

López, J., Coll, J., Haimel, M., Kandasamy, S., Tárraga, J., Furió-Tarí, P., Bari, W., Bleda, M., Rueda, A., Gräf, S., et al. (2017) · Nucleic Acids Res. · doi:10.1093/nar/gkx445 · Cited by 10 · see citing works

Multiomic Sequencing of Intermediate- to High-Risk Cutaneous Squamous Cell Carcinoma Identifies Critical Genes and Expression Patterns Associated with Disease and Poor Outcomes

Nassir, S., Yousif, M. L., Li, X., Severson, K. J., Hughes, A., Kechter, J. A., Hwang, A., Boudreaux, B. W., Bhullar, P. K., Zhang, N., et al. (2025) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2025.01.015 · Cited by 7 · see citing works

Standardized diagnostic algorithm for spitzoid lesions aids clinical decision-making and management: a case series from a Swiss reference center

Hilbers, M.-L., Waelchli, R., Mühleisen, B., Freiberger, S. N., Mangana, J., & Dummer, R. (2021) · Oncotarget · doi:10.18632/oncotarget.27854 · Cited by 7 · see citing works

Interactions between RASA2, CADM1, HIF1AN gene polymorphisms and body fatness with breast cancer: a population-based case-control study in China

Zhu, Z., Teng, Z., van Duijnhoven, F. J. B., Dong, M., Qian, Y., Hao, Y., Yang, J., Han, R., Su, J., Du, W., et al. (2017) · Oncotarget · doi:10.18632/oncotarget.21530 · Cited by 7 · see citing works

Genome-Wide Association Study Reveals Quantitative Trait Loci and Candidate Genes Associated with High Interferon-gamma Production in Holstein Cattle Naturally Infected with Mycobacterium Bovis

Badia-Bringué, G., Canive, M., Vázquez, P., Garrido, J. M., Fernández, A., Juste, R. A., Jiménez-Montero, J. A., González-Recio, Ó., & Alonso‐Hearn, M. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25116165 · Cited by 5 · see citing works

Loss of NF1 Accelerates Uveal and Intradermal Melanoma Tumorigenesis, and Oncogenic GNAQ Transforms Schwann Cells

Longakit, A. N., Urtatiz, O., Luty, A., Zhang, C., Hess, C., Yoo, A., Bourget, H., & Raamsdonk, C. D. V. (2025) · Cancer Research Communications · doi:10.1158/2767-9764.crc-24-0386 · Cited by 5 · see citing works

KLHL7 promotes hepatocellular carcinoma progression and molecular therapy resistance by degrading RASA2

Chen, L., Li, Y., & Chen, Y. (2023) · iScience · doi:10.1016/j.isci.2023.106914 · Cited by 5 · see citing works

The role of RASA2 in predicting radioresistance in lung cancer through regulation of p53

Li, J., Zong, Y., Tuo, Z., Liu, J., & Liu, J. (2024) · Translational Lung Cancer Research · doi:10.21037/tlcr-24-160 · Cited by 5 · see citing works

The Multiplex Genotyping Method for Single-Nucleotide Polymorphisms of Genes Associated with Obesity and Body Mass Index

Trifonova, E. A., Попович, А. А., Вагайцева, К. В., Бочарова, А. В., Gavrilenko, M. M., Ivanov, V. V., & Степанов, В. А. (2019) · Russian Journal of Genetics · doi:10.1134/s1022795419100144 · Cited by 5 · see citing works

Contemporary and potential future molecular diagnosis of melanoma

Gandolfi, G., Dallaglio, K., Longo, C., Moscarella, E., Lallas, A., Alfano, R., Argenziano, G., & Ciarrocchi, A. (2016) · Expert Review of Molecular Diagnostics · doi:10.1080/14737159.2016.1206473 · Cited by 4 · see citing works

Decoding directional genetic dependencies through orthogonal CRISPR/Cas screensPreprint

Boettcher, M., Tian, R., Blau, J. A., Markegard, E., Wu, D., Biton, A., Zaitlen, N., McCormick, F. P., Kampmann, M., & McManus, M. T. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/120170 · Cited by 5 · see citing works

Suppression of Class Switch Recombination to IgA by RASA2 and RASA3 through Inhibition of TGF-β Signaling

Mamand, S., Liu, H., Kashem, M. A., & Martín, A. (2024) · The Journal of Immunology · doi:10.4049/jimmunol.2400353 · Cited by 4 · see citing works

MEK Inhibition Reverses Aberrant Signaling in Melanoma Cells through Reorganization of NRas and BRAF in Self Nanoclusters

Yakovian, O., Sajman, J., Arafeh, R., Neve-Oz, Y., Alon, M., Samuels, Y., & Sherman, E. (2020) · Cancer Research · doi:10.1158/0008-5472.can-20-1205 · Cited by 4 · see citing works

Identifying targeted therapies for CBFA2T3::GLIS2 acute myeloid leukemia

Gonzales, F., Schneider, C., Alexe, G., Lin, S., Khalid, D., Alvarez, M., Basanthakumar, A. T., Ellegast, J. M., Merickel, L. A., Salhotra, S., et al. (2026) · Leukemia · doi:10.1038/s41375-025-02845-7 · Cited by 3 · see citing works

Genome Editing for Engineering the Next Generation of Advanced Immune Cell Therapies

de Lima, S. C. G., Fantacini, D. M. C., Furtado, I. P., Rossetti, R., Silveira, R. M., Covas, D. T., & de Souza, L. E. B. (2023) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-33325-5_6 · Cited by 2 · see citing works

Understanding the RAS in RASopathies

McCormick, F. P. (2024) · Springer eBooks · doi:10.1007/978-3-031-62945-7_20 · Cited by 2 · see citing works

Genetic Profiling of Malignant Melanoma Arising from an Ovarian Mature Cystic Teratoma: A Case Report

Nakamura, K., Aimono, E., Takamatsu, R., Tanishima, S., Tohyama, T., 笹野, 勝., Sakuma, H., & Nishihara, H. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22052436 · Cited by 2 · see citing works

Molecular Genetics of Melanoma Progression

Kohli, J. S., & Bennett, D. C. (2017) · Encyclopedia of Life Sciences · doi:10.1002/9780470015902.a0027340 · Cited by 2 · see citing works

Integrated methylome analysis identifies an epigenetically silenced tumor suppressor RASA4 in small cell lung cancer

Fu, M., Zhu, Q., Qi, J., Zhang, X., Wang, Z., Wang, J., Huang, X., Hu, Z., Wang, W., Hong, B., et al. (2025) · Communications Biology · doi:10.1038/s42003-025-09440-7 · Cited by 1 · see citing works

Promising Novel Biomarkers and Candidate Drugs or Herbs in Osteoarthritis: Evidence from Bioinformatics Analysis of High‐throughput Data

Qiao, L., Han, J., Wang, G., Yuan, T., & Gu, Y. (2022) · Current Bioinformatics · doi:10.2174/1574893617666220331090947 · Cited by 1 · see citing works

Melanomics: Comprehensive Molecular Analysis of Normal and Neoplastic Melanocytes

Nguyen, X. T. S., & Watson, I. R. (2018) · Springer eBooks · doi:10.1007/978-1-4614-7322-0_30-1 · Cited by 1 · see citing works

A QTL on chromosome 3q23 influences processing speed in humans

Knowles, E. E. M., Mathias, S. R., Mollon, J., Rodrigue, A., Koenis, M. M. G., Dyer, T. D., Göring, H. H. H., Curran, J. E., Olvera, R. L., Duggirala, R., et al. (2018) · Genes Brain & Behavior · doi:10.1111/gbb.12530 · Cited by 1 · see citing works

Principles of Targeted Therapy

Bollag, G. E., & Flaherty, K. T. (2018) · Springer eBooks · doi:10.1007/978-1-4614-7322-0_35-1

Novel Tumor Suppressive Role of the RAS GTPase-Activating Protein RASA5 to RAS Signaling Perturbation in Human CarcinomasPreprint

Li, L., Fan, Y., Huang, X., Zhong, L., Shu, X., Luo, J., Lu, L., Xiang, T., Chan, A. T. �., Yeo, W., et al. (2019) · SSRN Electronic Journal · doi:10.2139/ssrn.3357918

Melanomics: Comprehensive Molecular Analysis of Normal and Neoplastic Melanocytes

Nguyen, X. T. S., & Watson, I. R. (2019) · Springer eBooks · doi:10.1007/978-1-4614-7147-9_30

Principles of Targeted Therapy

Bollag, G. E., & Flaherty, K. T. (2019) · Springer eBooks · doi:10.1007/978-1-4614-7147-9_35

NRas activity is regulated by dynamic interactions with nanoscale signaling clusters at the plasma membrane

Yakovian, O., Sajman, J., Alon, M., Arafeh, R., Samuels, Y., & Sherman, E. (2022) · iScience · doi:10.1016/j.isci.2022.105282

Data from MEK Inhibition Reverses Aberrant Signaling in Melanoma Cells through Reorganization of NRas and BRAF in Self Nanoclusters

Yakovian, O., Sajman, J., Arafeh, R., Neve-Oz, Y., Alon, M., Samuels, Y., & Sherman, E. (2023) · doi:10.1158/0008-5472.c.6512581.v1

Inhibition of RAS as a novel therapeutic approach in Luminal B breast cancer.

Jigo, R. (2023) · doi:10.18297/etd/4150

Loss of neurofibromin accelerates uveal and dermal melanoma formation driven by GNAQPreprint

Longakit, A. N., Urtatiz, O., Luty, A., Zhang, C., Hess, C., Yoo, A., Bourget, H., & Raamsdonk, C. D. V. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.06.26.600903

Abstract LB-031: Deciphering distinct roles of RASA2 in melanomagenesis

Arafeh, R., Qutob, N., Emmanuel, R., Madore, J., Elkahloun, A. G., Wilmott, J. S., Gartner, J. J., Pizio, A. D., Rotkopf, R., Dutton‐Regester, K., et al. (2017) · Cancer Research · doi:10.1158/1538-7445.am2017-lb-031

RASA2 and NF1; two-negative regulators of Ras with complementary functions in melanoma

Arafeh, R., Pizio, A. D., Elkahloun, A. G., Dym, O., Niv, M. Y., & Samuels, Y. (2018) · Oncogene · doi:10.1038/s41388-018-0578-4 · Cited by 16 · see citing works

Abstract 1863: Inactivation of RASA1 promotes melanoma tumorigenesis via R-Ras activation

Hill, K. S., Sung, H., Kanchi, K., Messina, J. L., Lee, J., Kim, Y., Ding, L., Wilson, R. K., Weber, J. S., & Kim, M. (2016) · Cancer Research · doi:10.1158/1538-7445.am2016-1863

Abstract A05: Identification of RASA1 as a novel melanoma tumor suppressor gene

Sung, H., Kanchi, K., Messina, J. L., Lee, J., Ding, L., Wilson, R. K., Weber, J. S., & Kim, M. (2015) · Cancer Research · doi:10.1158/1538-7445.mel2014-a05

Abstract A2-25: Identification of RASA1 as a novel melanoma tumor suppressor gene

Sung, H., Kanchi, K., Messina, J. L., Lee, J., Kim, Y., Ding, L., Wilson, R. K., Weber, J. S., & Kim, M. (2015) · Cancer Research · doi:10.1158/1538-7445.transcagen-a2-25