Sharp, Stephen J.

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

DIAGRAM Consortium, Dupuis, J., GIANT Consortium, Global BPgen Consortium, Anders Hamsten on behalf of Procardis Consortium, the MAGIC investigators, Langenberg, C., Prokopenko, I., Saxena, R., Soranzo, N., et al. (2010) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 2,166

Sedentary behaviour and risk of all-cause, cardiovascular and cancer mortality, and incident type 2 diabetes: a systematic review and dose response meta-analysis

Patterson, R., McNamara, E., Tainio, M., de Sá, T. H., Smith, A. D., Sharp, S. J., Edwards, P., Woodcock, J., Brage, S., & Wijndaele, K. (2018) · European Journal of Epidemiology

Physical Activity and HealthNutritional Studies and Diet

Cited by 1,423

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

Swerdlow, D. I., Preiss, D., Kuchenbaecker, K. B., Holmes, M. V., Engmann, J. E. L., Shah, T., Sofat, R., Stender, S., Johnson, P. C. D., Scott, R. A., et al. (2015) · The Lancet

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 680

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

Holmes, M. V., Dale, C. E., Zuccolo, L., Silverwood, R. J., Guo, Y., Ye, Z., Prieto-Merino, D., Dehghan, A., Trompet, S., Wong, A., et al. (2014) · BMJ

Alcohol Consumption and Health EffectsGenetic Associations and Epidemiology

Cited by 669

Physical distancing interventions and incidence of coronavirus disease 2019: natural experiment in 149 countries

Islam, N., Sharp, S. J., Chowell, G., Shabnam, S., Kawachi, I., Lacey, B., Massaro, J. M., D’Agostino, R. B., & White, M. (2020) · BMJ

COVID-19 epidemiological studiesCOVID-19 Prevention and Impact

Cited by 601

Differences in the prospective association between individual plasma phospholipid saturated fatty acids and incident type 2 diabetes: the EPIC-InterAct case-cohort study

Forouhi, N. G., Koulman, A., Sharp, S. J., Imamura, F., Kröger, J., Schulze, M. B., Crowe, F. L., Huerta, J. M., Guevara, M., Beulens, J. W., et al. (2014) · The Lancet Diabetes & Endocrinology

Fatty Acid Research and HealthNutritional Studies and Diet

Cited by 557

Early age at menarche associated with cardiovascular disease and mortality

Lakshman, R., Forouhi, N. G., Sharp, S. J., Luben, R., Bingham, S. A., Khaw, K.-T., Wareham, N. J., & Ong, K. K. (2009) · The Journal of Clinical Endocrinology & Metabolism

Menopause: Health Impacts and TreatmentsHypothalamic control of reproductive hormones

Cited by 542

Effect of early intensive multifactorial therapy on 5-year cardiovascular outcomes in individuals with type 2 diabetes detected by screening (ADDITION-Europe): a cluster-randomised trial

Griffin, S. J., Borch-Johnsen, K., Davies, M. J., Khunti, K., Rutten, G. E., Sandbæk, A., Sharp, S. J., Simmons, R. K., van den Donk, M., Wareham, N. J., et al. (2011) · The Lancet

Health Promotion and Cardiovascular PreventionDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 462

Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis

Lotta, L. A., Scott, R. A., Sharp, S. J., Burgess, S., Luan, J., Tillin, T., Schmidt, A. F., Imamura, F., Stewart, I. D., Perry, J. R. B., et al. (2016) · PLOS Medicine

Genetic Associations and EpidemiologyDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 417

Impact of common genetic determinants of hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis

Wheeler, E., Leong, A., Liu, C.-T., Hivert, M.-F., Strawbridge, R. J., Podmore, C., Li, M., Yao, J., Sim, X., Hong, J., et al. (2017) · PLOS Medicine

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 408

Association Between Low-Density Lipoprotein Cholesterol–Lowering Genetic Variants and Risk of Type 2 Diabetes: A Meta-analysis

Lotta, L. A., Sharp, S. J., Burgess, S., Perry, J. R. B., Stewart, I. D., Willems, S. M., Luan, J., Ardanaz, E., Arriola, L., Balkau, B., et al. (2016) · JAMA

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 394

Wearable-device-measured physical activity and future health risk

Strain, T., Wijndaele, K., Dempsey, P. C., Sharp, S. J., Pearce, M., Jeon, J., Lindsay, T., Wareham, N., & Brage, S. (2020) · Nature Medicine

Physical Activity and HealthContext-Aware Activity Recognition Systems

Cited by 355

The UK‐PBC risk scores: Derivation and validation of a scoring system for long‐term prediction of end‐stage liver disease in primary biliary cholangitis

Carbone, M., Sharp, S. J., Flack, S., Paximadas, D., Spiess, K., Adgey, C., Griffiths, L., Lim, R., Trembling, P., Williamson, K., et al. (2016) · Hepatology

Liver Diseases and ImmunityPediatric Hepatobiliary Diseases and Treatments

Cited by 354

Factors associated with the presence of diabetic ketoacidosis at diagnosis of diabetes in children and young adults: a systematic review

Usher-Smith, J. A., Thompson, M. J., Sharp, S. J., & Walter, F. M. (2011) · BMJ

Diabetes Management and ResearchDiabetes and associated disorders

Cited by 348

Physical activity and all-cause mortality across levels of overall and abdominal adiposity in European men and women: the European Prospective Investigation into Cancer and Nutrition Study (EPIC)

Ekelund, U., Ward, H. A., Norat, T., Luan, J., May, A. M., Weiderpass, E., Sharp, S. J., Overvad, K., Østergaard, J. N., Tjønneland, A., et al. (2015) · The American Journal of Clinical Nutrition

Physical Activity and HealthObesity, Physical Activity, Diet

Cited by 347

Human gain-of-function MC4R variants show signaling bias and protect against obesity

Lotta, L. A., Mokrosiński, J., Mendes de Oliveira, E., Li, C., Sharp, S. J., Luan, J., Brouwers, B., Ayinampudi, V., Bowker, N., Kerrison, N., et al. (2019) · Cell

Regulation of Appetite and ObesityReceptor Mechanisms and Signaling

Cited by 284

Television viewing time independently predicts all-cause and cardiovascular mortality: the EPIC Norfolk Study

Wijndaele, K., Brage, S., Besson, H., Khaw, K.-T., Sharp, S. J., Luben, R., Wareham, N. J., & Ekelund, U. (2011) · International Journal of Epidemiology

Physical Activity and HealthNutritional Studies and Diet

Cited by 278

The spectrum effect in tests for risk prediction, screening, and diagnosis

Usher-Smith, J. A., Sharp, & Griffin, S. J. (2016) · BMJ

Statistical Methods in EpidemiologyMeta-analysis and systematic reviews

Cited by 250

Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors

Lotta, L. A., Wittemans, L. B. L., Zuber, V., Stewart, I. D., Sharp, S. J., Luan, J., Day, F. R., Li, C., Bowker, N., Cai, L., et al. (2018) · JAMA

Genetic Associations and EpidemiologyDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 229

The amount and type of dairy product intake and incident type 2 diabetes: results from the EPIC-InterAct Study

Sluijs, I., Forouhi, N. G., Beulens, J. W., van der Schouw, Y. T., Agnoli, C., Arriola, L., Balkau, B., Barricarte, A., Boeing, H., Bueno-de-Mesquita, H. B., et al. (2012) · The American Journal of Clinical Nutrition

Nutritional Studies and DietProbiotics and Fermented Foods

Cited by 223

Change in objectively measured physical activity during the transition to adolescence

Corder, K., Sharp, S. J., Atkin, A. J., Griffin, S. J., Jones, A. P., Ekelund, U., & van Sluijs, E. M. F. (2015) · British Journal of Sports Medicine

Physical Activity and HealthObesity, Physical Activity, Diet

Cited by 220

The absolute and relative risk of type 2 diabetes after gestational diabetes: A systematic review and meta-analysis of 129 studies

Dennison, R. A., Chen, E. S., Green, M. E., Legard, C., Kotecha, D., Farmer, G., Sharp, S. J., Ward, R. J., Usher-Smith, J. A., & Griffin, S. J. (2021) · Diabetes Research and Clinical Practice

Gestational Diabetes Research and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 214

Associations between potentially modifiable risk factors and Alzheimer disease: a mendelian randomization study

Østergaard, S. D., Mukherjee, S., Sharp, S. J., Proitsi, P., Lotta, L. A., Day, F., Perry, J. R. B., Boehme, K. L., Walter, S., Kauwe, J. S., et al. (2015) · PLOS Medicine

Dementia and Cognitive Impairment ResearchGenetic Associations and Epidemiology

Cited by 203

Prevalence of autism in mainland China, Hong Kong and Taiwan: a systematic review and meta-analysis

Sun, X., Allison, C., Matthews, F. E., Sharp, S. J., Auyeung, B., Baron-Cohen, S., & Brayne, C. (2013) · Molecular Autism

Autism Spectrum Disorder ResearchChild Nutrition and Feeding Issues

Cited by 200