Ljungman, Mats

Rate of elongation by RNA polymerase II is associated with specific gene features and epigenetic modifications

Veloso, A., Kirkconnell, K. S., Magnuson, B., Biewen, B., Paulsen, M. T., Wilson, T. E., & Ljungman, M. (2014) · Genome Research

Genomics and Chromatin DynamicsRNA Research and Splicing

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H2AX phosphorylation after UV irradiation is triggered by DNA repair intermediates and is mediated by the ATR kinase

Hanasoge, S., & Ljungman, M. (2007) · Carcinogenesis

DNA Repair MechanismsEffects of Radiation Exposure

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Hsp90-binding immunophilins link p53 to dynein during p53 transport to the nucleus

Galigniana, M. D., Harrell, J. M., O'Hagen, H. M., Ljungman, M., & Pratt, W. B. (2004) · Journal of Biological Chemistry

Heat shock proteins researchCancer-related Molecular Pathways

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Genome-wide de novo L1 Retrotransposition Connects Endonuclease Activity with Replication

Flasch, D. A., Macia, Á., Sánchez, L., Ljungman, M., Heras, S. R., García-Pérez, J. L., Wilson, T. E., & Moran, J. V. (2019) · Cell

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

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ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation

van der Weegen, Y., de Lint, K., van den Heuvel, D., Nakazawa, Y., Mevissen, T. E. T., van Schie, J. J. M., San Martin Alonso, M., Boer, D. E. C., González-Prieto, R., Narayanan, I. V., et al. (2021) · Nature Cell Biology

DNA Repair MechanismsGenomics and Chromatin Dynamics

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A CSB-PAF1C axis restores processive transcription elongation after DNA damage repair

van den Heuvel, D., Spruijt, C. G., González-Prieto, R., Kragten, A., Paulsen, M. T., Zhou, D., Wu, H., Apelt, K., van der Weegen, Y., Yang, K., et al. (2021) · Nature Communications

DNA Repair MechanismsGenomics and Chromatin Dynamics

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A CSB-PAF1C axis restores processive transcription elongation after DNA damage repair

van den Heuvel, D., Spruijt, C. G., González-Prieto, R., Kragten, A., Paulsen, M. T., Zhou, D., Wu, H., Apelt, K., van der Weegen, Y., Yang, K., et al. (2020) · Nature Communications

DNA Repair MechanismsGenomics and Chromatin Dynamics

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STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair

van den Heuvel, D., Rodríguez-Martínez, M., van der Meer, P. J., Moreno, N. N., Park, J., Kim, H.-S., van Schie, J. J. M., Wondergem, A. P., D’Souza, A., Yakoub, G., et al. (2024) · Cell

DNA Repair MechanismsGenomics and Chromatin Dynamics

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KDM6A regulates cell plasticity and pancreatic cancer progression by noncanonical activin pathway

Yi, Z., Wei, S., Jin, L., Jeyarajan, S., Yang, J., Gu, Y., Kim, H. S., Schechter, S., Lu, S., Paulsen, M. T., et al. (2022) · Cellular and Molecular Gastroenterology and Hepatology

Pancreatic and Hepatic Oncology ResearchEpigenetics and DNA Methylation

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Lack of functional pRb results in attenuated recovery of mRNA synthesis and increased apoptosis following UV radiation in human breast cancer cells

Billecke, C. A., Ljungman, M. E., McKay, B. C., Rehemtulla, A., Taneja, N., & Ethier, S. P. (2002) · Oncogene

Cancer-related Molecular PathwaysCell death mechanisms and regulation

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Principles of mRNA control by human PUM proteins elucidated from multimodal experiments and integrative data analysis

Wolfe, M. B., Schagat, T. L., Paulsen, M. T., Magnuson, B., Ljungman, M., Park, D., Zhang, C., Campbell, Z. T., Goldstrohm, A. C., & Freddolino, P. L. (2020) · RNA

RNA Research and SplicingRNA and protein synthesis mechanisms

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Principles of mRNA control by human PUM proteins elucidated from multi-modal experiments and integrative data analysis

Wolfe, M. B., Schagat, T. L., Paulsen, M. T., Magnuson, B., Ljungman, M., Park, D., Zhang, C., Campbell, Z. T., Goldstrohm, A. C., & Freddolino, P. L. (2020) · RNA

RNA Research and SplicingRNA and protein synthesis mechanisms

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