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CRL3ARMC5 ubiquitin ligase and Integrator phosphatase form parallel mechanisms to control early stages of RNA Pol II transcription

Cacioppo, R., Gillis, A., Shlamovitz, I., Zeller, A., Castiblanco, D., Crisp, A., Haworth, B., Arabiotorre, A., Abyaneh, P., Bao, Y., et al. (2024) · Molecular Cell · doi:10.1016/j.molcel.2024.11.024 · Cited by 23 · see citing works

XPG: a multitasking genome caretaker

Muniesa-Vargas, A., Theil, A. F., Ribeiro-Silva, C., Vermeulen, W., & Lans, H. (2022) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-022-04194-5 · Cited by 23 · see citing works

A half century of exploring DNA excision repair in chromatin

Smerdon, M. J., Wyrick, J. J., & Delaney, S. (2023) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2023.105118 · Cited by 23 · see citing works

A disease-associated XPA allele interferes with TFIIH binding and primarily affects transcription-coupled nucleotide excision repair

van den Heuvel, D., Kim, M., Wondergem, A. P., van der Meer, P. J., Witkamp, M., Lambregtse, F., Kim, H.-S., Kan, F., Apelt, K., Kragten, A., et al. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2208860120 · Cited by 21 · see citing works

Cockayne Syndrome Linked to Elevated R-Loops Induced by Stalled RNA Polymerase II during Transcription Elongation

Zhang, X., Xu, J., Hu, J., Zhang, S., Hao, Y., Zhang, D., Qian, H., Wang, D., & Fu, X. (2024) · Nature Communications · doi:10.1038/s41467-024-50298-w · Cited by 19 · see citing works

The small CRL4CSA ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics

Llerena Schiffmacher, D. A., Lee, S.-H., Kliza, K. W., Theil, A. F., Akita, M., Helfricht, A., Bezstarosti, K., Gonzalo-Hansen, C., van Attikum, H., Verlaan-de Vries, M., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-50584-7 · Cited by 19 · see citing works

Transcription-coupled AID deamination damage depends on ELOF1-associated RNA polymerase II

Dai, P., Tan, Y., Luo, Y., Liu, T., Huang, Y., Shang, Y., Huang, M. E., Liu, X., Zhang, S., Wang, Y., et al. (2025) · Molecular Cell · doi:10.1016/j.molcel.2025.02.006 · Cited by 17 · see citing works

Epigenetic Regulation of Nucleotide Excision Repair

Li, W., Jones, K., Burke, T. J., Hossain, M. A., & Lariscy, L. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.847051 · Cited by 17 · see citing works

The role of Transcription Factor IIH complex in nucleotide excision repair

Hoag, A., Duan, M., & Mao, P. (2023) · Environmental and Molecular Mutagenesis · doi:10.1002/em.22568 · Cited by 17 · see citing works

MMS22L-TONSL functions in sister chromatid cohesion in a pathway parallel to DSCC1-RFC

van Schie, J. J. M., de Lint, K., Pai, G. M., Rooimans, M. A., Wolthuis, R. M. F., & de Lange, J. (2022) · Life Science Alliance · doi:10.26508/lsa.202201596 · Cited by 17 · see citing works

Novel insights into bulky DNA damage formation and nucleotide excision repair from high-resolution genomics.

Cohen, Y., & Adar, S. (2023) · DNA Repair · doi:10.1016/j.dnarep.2023.103549 · Cited by 12 · see citing works

BIRC2–BIRC3 amplification: a potentially druggable feature of a subset of head and neck cancers in patients with Fanconi anemia

Roohollahi, K., de Jong, Y., Pai, G. M., Zaini, M. A., de Lint, K., Sie, D., Rooimans, M. A., Rockx, D., Hoskins, E. E., Ameziane, N., et al. (2022) · Scientific Reports · doi:10.1038/s41598-021-04042-9 · Cited by 16 · see citing works

The molecular basis of human transcription-coupled DNA repair

van der Meer, P. J., & Luijsterburg, M. S. (2025) · Nature Cell Biology · doi:10.1038/s41556-025-01715-9 · Cited by 17 · see citing works

CRISPR screens in sister chromatid cohesion defective cells reveal PAXIP1-PAGR1 as regulator of chromatin association of cohesin

van Schie, J. J. M., de Lint, K., Molenaar, T. M., Gines, M. M., Balk, J. A., Rooimans, M. A., Roohollahi, K., Pai, G. M., Borghuis, L., Ramadhin, A. R., et al. (2023) · Nucleic Acids Research · doi:10.1093/nar/gkad756 · Cited by 16 · see citing works

Mechanisms of transcription-coupled repair and DNA damage surveillance in health and disease

van Sluis, M., Gonzalo-Hansen, C., Li, Q., Lans, H., Wang, D., & Marteijn, J. A. F. (2025) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-025-00915-3 · Cited by 21 · see citing works

Genome-wide mapping of protein–DNA damage interaction by PADD-seq

Zhu, Y., Tan, Y., Li, L., Xiang, Y., Huang, Y., Zhang, X., Yin, J., Li, J., Lan, F., Qian, M., et al. (2023) · Nucleic Acids Research · doi:10.1093/nar/gkad008 · Cited by 14 · see citing works

CS proteins and ubiquitination: orchestrating DNA repair with transcription and cell division

Costanzo, F., Paccosi, E., Proietti‐De‐Santis, L., & Egly, J. (2024) · Trends in Cell Biology · doi:10.1016/j.tcb.2024.06.002 · Cited by 14 · see citing works

Transcription-coupled repair of DNA–protein crosslinks

Carnie, C. J., Jackson, S. P., & Stingele, J. (2024) · Trends in Cell Biology · doi:10.1016/j.tcb.2024.11.003 · Cited by 16 · see citing works

Transcription elongation factor ELOF1 is required for efficient somatic hypermutation and class switch recombination

Wu, L., Yadavalli, A. D., Šenigl, F., Matos-Rodrigues, G. E., Xu, D., Pintado-Urbanc, A. P., Simon, M. D., Wu, W., Nussenzweig, A., & Schatz, D. G. (2024) · Molecular Cell · doi:10.1016/j.molcel.2025.02.007 · Cited by 14 · see citing works

The mutational impact of Illudin S on human cells

Casimir, L., Zimmer, S., Racine-Brassard, F., Jacques, P., & Maréchal, A. (2022) · DNA repair · doi:10.1016/j.dnarep.2022.103433 · Cited by 12 · see citing works

Multiple structures of RNA polymerase II isolated from human nuclei by ChIP-CryoEM analysis

Kujirai, T., Kato, J., Yamamoto, K., Hirai, S., Fujii, T., Maehara, K., Harada, A., Negishi, L., Ogasawara, M., Yamaguchi, Y., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-59580-x · Cited by 13 · see citing works

DNA Damage-Induced RNAPII Degradation and Its Consequences in Gene Expression

Muñoz, J. C., Beckerman, I., Choudhary, R., Bouvier, L. A., & Muñoz, M. J. (2022) · Genes · doi:10.3390/genes13111951 · Cited by 12 · see citing works

Structural basis of RECQL5-induced RNA polymerase II transcription braking and subsequent reactivation

Zhang, L., Gordiyenko, Y., Morgan, T., Franco, C., Tufegdžić Vidaković, A., & Zhang, S. (2025) · Nature Structural &amp; Molecular Biology · doi:10.1038/s41594-025-01586-6 · Cited by 12 · see citing works

Transcription-Coupled Nucleotide Excision Repair: A Faster Solution or the Only Option?

Khobta, A., & Sarmini, L. (2025) · Biomolecules · doi:10.3390/biom15071026 · Cited by 12 · see citing works

Opposite roles of transcription elongation factors Spt4/5 and Elf1 in RNA polymerase II transcription through B-form versus non-B DNA structures

Xu, J., Chong, J., & Wang, D. (2021) · Nucleic Acids Research · doi:10.1093/nar/gkab240 · Cited by 10 · see citing works

Mutations found in cancer patients compromise DNA binding of the winged helix protein STK19

Li, J., Ma, X., Wang, X., Hu, X., Fang, S., Jin, G., Liu, K., & Dong, Z. (2024) · Scientific Reports · doi:10.1038/s41598-024-64840-9 · Cited by 9 · see citing works

Molecular model of TFIIH recruitment to the transcription-coupled repair machinery

Paul, T., Yan, C., Yu, J., Tsutakawa, S. E., Tainer, J. A., Wang, D., & Ivanov, I. N. (2025) · Nature Communications · doi:10.1038/s41467-025-57593-0 · Cited by 11 · see citing works

New roles for elongation factors in RNA polymerase II ubiquitylation and degradation

Reese, J. C. (2023) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2023.194956 · Cited by 10 · see citing works

Transcription‐coupled repair – mechanisms of action, regulation, and associated human disorders

Nakazawa, Y., Oka, Y., Matsunaga, T., & Ogi, T. (2024) · FEBS Letters · doi:10.1002/1873-3468.15073 · Cited by 8 · see citing works

Transcription-Coupled Repair and R-Loop Crosstalk in Genome Stability

Jeon, J., & Kang, T. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26083744 · Cited by 8 · see citing works

Transcription‐coupled repair: tangled up in convoluted repair

Schiffmacher, D. A. L., Pai, Y. J., Pines, A., & Vermeulen, W. (2025) · FEBS Journal · doi:10.1111/febs.70104 · Cited by 9 · see citing works

Hierarchical mechanisms control the clearance of DNA lesion–stalled RNA polymerase II

van der Meer, P. J., Yakoub, G., Tsukada, K., Nakazawa, Y., Ogi, T., & Luijsterburg, M. S. (2026) · Nature Communications · doi:10.1038/s41467-026-68413-4 · Cited by 9 · see citing works

Elongation factor 1 is a component of the Arabidopsis RNA polymerase II elongation complex and associates with a subset of transcribed genes

Markusch, H., Holzinger, P., Obermeyer, S., Thorbecke, C., Bruckmann, A., Babl, S., Längst, G., Osakabe, A., Berger, F., & Grasser, K. D. (2023) · New Phytologist · doi:10.1111/nph.18724 · Cited by 8 · see citing works

Live-cell imaging of endogenous CSB-mScarletI as a sensitive marker for DNA-damage-induced transcription stress

Zhou, D., Yu, Q. S., Janssens, R. C., & Marteijn, J. A. F. (2024) · Cell Reports Methods · doi:10.1016/j.crmeth.2023.100674 · Cited by 8 · see citing works

Clearance of DNA damage-arrested RNAPII is selectively impaired in Cockayne syndrome cellsPreprint

van der Meer, P. J., Yakoub, G., Nakazawa, Y., Ogi, T., & Luijsterburg, M. S. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.05.17.594644 · Cited by 7 · see citing works

RNAPII response to transcription‐blocking DNA lesions in mammalian cells

Wang, J., Sadurnì, M. M., & Saponaro, M. (2022) · FEBS Journal · doi:10.1111/febs.16561 · Cited by 7 · see citing works

Poly-(ADP-ribose) serves as a scaffold for the methyltransferase METTL3/14 complex in the DNA damage response

Gonzalez-Leal, C., Cai, J., de Groot, B. A. F. J., Wegerer, A., Preißer, J., Luijsterburg, M. S., & Ladurner, A. G. (2025) · Nucleic Acids Research · doi:10.1093/nar/gkaf244 · Cited by 6 · see citing works

PARP1 and PARylation facilitate transcription-coupled DNA repair by stabilizing the CSB–RNAPII complex

Robu, M., Shah, R. G., van den Heuvel, D., Coulombe, Y., Bazin, M., van der Woude, M., Kragten, A., Lans, H., Pascal, J. M., Masson, J., et al. (2025) · Nucleic Acids Research · doi:10.1093/nar/gkaf1303 · Cited by 6 · see citing works

CFAP20 salvages arrested RNAPII from the path of co-directional replisomes

Uruci, S., Boer, D. E. C., Chrystal, P. W., Lalonde, M., Παναγόπουλος, Α., Yakoub, G., Kirdök, İ., de Lint, K., van der Woude, M., Wendel, T. J., et al. (2026) · Nature · doi:10.1038/s41586-025-09943-7 · Cited by 6 · see citing works

Insights Into Cockayne Syndrome Type B: What Underlies Its Pathogenesis?

Afonso‐Reis, R., Madeira, C. R., Brito, D. V. C., & Nóbrega, C. (2025) · Aging Cell · doi:10.1111/acel.70136 · Cited by 6 · see citing works

The ELOF(1)ant in the room of TCR

Carnie, C. J., & Jackson, S. P. (2021) · Nature Cell Biology · doi:10.1038/s41556-021-00698-7 · Cited by 6 · see citing works

Tools for Decoding Ubiquitin Signaling in DNA Repair

Foster, B., Attwood, M., & Gibbs‐Seymour, I. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.760226 · Cited by 5 · see citing works

Pharmacologic interrogation of USP28 cellular function in p53 signaling

Bratt, A. S., Kilgas, S., Guzman, M. I. T., Magin, R. S., Maisonet, I. J., Starnbach, C. A., Teh, W. P., Varca, A. C., Hu, B., Guzman, E. T., et al. (2025) · Cell chemical biology · doi:10.1016/j.chembiol.2025.08.002 · Cited by 5 · see citing works

Interplay of the Tfb1 pleckstrin homology domain with Rad2 and Rad4 in transcription coupled and global genomic nucleotide excision repair

Gong, W., Holmberg, H., Lu, C., Huang, M., & Li, S. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae286 · Cited by 5 · see citing works

Elf1 promotes transcription-coupled repair in yeast by using its C-terminal domain to bind TFIIH

Selvam, K., Xu, J., Wilson, H. E., Oh, J., Li, Q., Wang, D., & Wyrick, J. J. (2024) · Nature Communications · doi:10.1038/s41467-024-50539-y · Cited by 4 · see citing works

Transcription and genome integrity

Ljungman, M. E. (2022) · DNA repair · doi:10.1016/j.dnarep.2022.103373 · Cited by 5 · see citing works

Targeting Genome Stability to Mitigate Human Aging and Disease

Toiber, D., & Schumacher, B. (2025) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev-pathmechdis-042624-105942 · Cited by 4 · see citing works

FeaSion decodes the regulatory landscape and functional diversity of RNA polymerase II CTD phosphorylation

Zhu, J., Bao, L., Xu, S., & Ji, X. (2025) · Science Advances · doi:10.1126/sciadv.adz2345 · Cited by 5 · see citing works

Integrator subunit INTS12 links ribotoxic stress to transcription-coupled nucleotide excision repair

Li, Z., Li, R., Yang, M., Huang, Y., Yang, J., Zhu, Q., Shao, Y., Zhao, W., Fu, H., Xiao, Y.-X., et al. (2026) · Nature Structural & Molecular Biology · doi:10.1038/s41594-026-01766-y · Cited by 4 · see citing works

A Practical Site-specific Method for the Detection of Bulky DNA Damages

Hassanain, H., Tseitline, D., Hacohen, T., Yifrach, A., Kirshenbaum, A., Lavi, B., Parnas, A., & Adar, S. (2024) · Journal of Molecular Biology · doi:10.1016/j.jmb.2024.168450 · Cited by 3 · see citing works

STK19: a critical factor coordinating transcription-coupled DNA repair

Li, S., & Li, W. (2025) · Protein & Cell · doi:10.1093/procel/pwaf007 · Cited by 3 · see citing works

Rpb7 represses transcription-coupled nucleotide excision repair

Gong, W., & Li, S. (2023) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2023.104969 · Cited by 3 · see citing works

Prolonged stalling of RNA Polymerase II at DNA damage explains phenotypical differences between Cockayne and UV-sensitive syndromesPreprint

Gonzalo-Hansen, C., Steurer, B., Janssens, R. C., Zhou, D., van Sluis, M., Lans, H., & Marteijn, J. A. F. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.05.17.541110 · Cited by 3 · see citing works

STK19 drives Transcription-Coupled Repair by stimulating repair complex stability, Pol II ubiquitylation and TFIIH recruitmentPreprint

Ramadhin, A. R., Lee, S.-H., Zhou, D., Salmazo, A. P. T., Gonzalo-Hansen, C., van Sluis, M., Blom, C. M. A., Janssens, R. C., Raams, A., Dekkers, D. H. W., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.07.22.604556 · Cited by 3 · see citing works

Mechanisms of DNA repair and mutagenesis induced by acetaldehyde, acrolein, aristolochic acids, and vinyl chloride

Jones, K., Dye, E., Gilkes, N., Xia, D., Jiang, S., & Li, W. (2025) · Journal of Environmental Science and Health Part C · doi:10.1080/26896583.2025.2545086 · Cited by 2 · see citing works

Targeted CRISPR knockout screening identifies known and novel chemogenomic interactions between DNA damaging agents and DNA repair genes

Heer, C. D., Elia, J. L., Menon, V., Johnson, S. S., Arbelaez, S. R., Friedman, S., Lopez-Giraldez, F., Sundaram, R. K., Herzon, S. B., Bindra, R. S., et al. (2025) · NAR Cancer · doi:10.1093/narcan/zcaf052 · Cited by 2 · see citing works

Search, verify and excise-lesion recognition in NER

Kuper, J., & Kisker, C. (2026) · DNA repair · doi:10.1016/j.dnarep.2026.103922 · Cited by 2 · see citing works

The interaction of XPG with TFIIH through p62 and XPD is required for the completion of nucleotide excision repair

Kim, M., Jeong, E., Park, J., D’Souza, A., Tsai, M.-S., Yan, C., Ivanov, I., Chazin, W. J., Kim, H. S., & Schärer, O. D. (2026) · Nucleic Acids Research · doi:10.1093/nar/gkag078 · Cited by 2 · see citing works

PAF1C restores transcription after DNA damage independently of promoting histone mark deposition

van Schie, J. J. M., de Groot, B. A. F. J., van den Heuvel, D., & Luijsterburg, M. S. (2026) · EMBO Reports · doi:10.1038/s44319-026-00761-0 · Cited by 2 · see citing works

Polymerase face-off: emerging concepts in transcription-replication coordination

Uruci, S., Lalonde, M., Luijsterburg, M. S., & Hamperl, S. (2026) · EMBO Reports · doi:10.1038/s44319-026-00800-w · Cited by 2 · see citing works

Histone variant H2A.Z is needed for efficient transcription-coupled NER and genome integrity in UV challenged yeast cells

Gaillard, H., Ciudad, T., Aguilera, A., & Wellinger, R. E. (2024) · PLoS Genetics · doi:10.1371/journal.pgen.1011300 · Cited by 2 · see citing works

Evidence that ARK2N is not a core factor in transcription-coupled DNA repair

van Schie, J. J. M., Brussee, S. J., & Luijsterburg, M. S. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2425178122 · Cited by 2 · see citing works

Stabilization of AFF1 by PARylation ensures transcriptional restart after DNA damage

Zhu, F., Fu, H., Zhu, W., Li, C., Yang, M., Feng, Z., Shao, Y., Li, Z., Guo, Y., Huang, M., et al. (2025) · Nature Chemical Biology · doi:10.1038/s41589-025-02045-5 · Cited by 2 · see citing works

RNA polymerase II processing facilitates DNA repair and prevents DNA damage-induced neuronal and developmental failurePreprint

van der Woude, M., Thijssen, K. L., Sabatella, M., Marteijn, J. A. F., Vermeulen, W., & Lans, H. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.03.21.644538 · Cited by 2 · see citing works

Stalling of elongating Pol II triggers Ser7 phosphorylation in trans to drive transcription recoveryPreprint

Shlamovitz, I., Bao, Y., Toteva, T., Crisp, A., Ye, S., Wingett, S., Cacioppo, R., Edmondson, A., Castiblanco, D., Boemo, M. A., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.04.692291 · Cited by 2 · see citing works

ELOF1 is a core component of the promoter-proximal paused RNA polymerase II complexPreprint

Nunez, R. J. V., Bressin, A., Shao, Z., Mayer, A., & Vos, S. M. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.05.26.728003 · Cited by 2 · see citing works

Transcription-coupled repair: protecting genome across generations

Pani, B., & Nudler, E. (2025) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2025.102385 · Cited by 1 · see citing works

K63-linked ubiquitylation of S2P–RNAPII regulates transcription in a DNAPK inter-dependent manner in response to double-strand breaks

Pantazi, V., Smith, P., Páhi, Z. G., Katona, M., Pap, Á., Darula, Z., Fischer, R., Vendrell, I., Kessler, B. M., van Vugt, M. A. T. M., et al. (2026) · Nucleic Acids Research · doi:10.1093/nar/gkag347 · Cited by 1 · see citing works

The Role of TFIIH Complex in Nucleotide Excision RepairPreprint

Hoag, A., Duan, M., & Mao, P. (2023) · doi:10.22541/au.168173465.59820001/v1 · Cited by 1 · see citing works

The histone variant H2A.Z is required for efficient transcription-coupled NER and to maintain genome integrity in UV challenged yeast cellsPreprint

Gaillard, H., Ciudad, T., Aguilera, A., & Wellinger, R. E. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.05.13.593813 · Cited by 1 · see citing works

Ubiquitylation of RNA Polymerase II Controls Early Stages of the Transcription CyclePreprint

Cacioppo, R., Gillis, A., Shlamovitz, I., Zeller, A., Castiblanco, D., Crisp, A., Haworth, B., Arabiotorre, A., Abyaneh, P., Bao, Y., et al. (2024) · SSRN Electronic Journal · doi:10.2139/ssrn.4826625

Finding novel vulnerabilities of hypomorphic BRCA1 allelesPreprint

Schreuder, A., de Lint, K., Gois, M. M., Kampen, R. A., Alonso, M. S. M., Nootenboom, I., Garzero, V., Wolthuis, R. M. F., & Noordermeer, S. M. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.05.24.595688

Chromatin and transcription

Morse, R. H. (2024) · Elsevier eBooks · doi:10.1016/b978-0-12-814809-9.00009-3

RNA Polymerase II subunits overexpressions induce genome instability and deregulate transcriptionPreprint

Sadurnì, M. M., Jones, M. L., Pavlou, L., Radi, M., Kompocholi, S., Passaretti, P., Gambus, A., Gregersen, L. H., & Saponaro, M. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.11.20.622938

Bypass of Blocking Lesions by RNAPII Impairs the Transcriptional DNA Damage ResponsePreprint

Bañuelos, C. P., Caeiro, L. D., Cingaram, P. R., Beckedorff, F., Morey, L., Cortes, D. B., Shiekhattar, R., & Verdún, R. E. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.04.28.651040

PAF1C-driven restoration of RNAPII elongation after DNA damage occurs independently of transcription-associated histone mark depositionPreprint

van Schie, J. J. M., de Groot, B. A. F. J., & Luijsterburg, M. S. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.07.23.666359

A Splicing Variant in XPA Results in Delayed Onset of Clinical Features of Xeroderma Pigmentosum

van den Heuvel, A., Wondergem, A. P., Kim, M., Breet, I., Kim, H. S., Fawcett, H., Fassihi, H., Lehmann, A. R., Schärer, O. D., & Luijsterburg, M. S. (2025) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2025.08.047

Protocol for imaging-based quantification of RNAPII clearance during transcription-coupled DNA repair

de Groot, B. A. F. J., van der Meer, P. J., van den Heuvel, D., & Luijsterburg, M. S. (2025) · STAR Protocols · doi:10.1016/j.xpro.2025.104213

Unravelling molecular mechanisms in transcription-coupled nucleotide excision repair

van der Weegen, Y. (2022) · Leiden Repository (Leiden University)

Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability

Geijer, M. E., Zhou, D., Selvam, K., Steurer, B., Mukherjee, C., Evers, B., Cugusi, S., van Toorn, M., van der Woude, M., Janssens, R. C., et al. (2021) · Nature Cell Biology · doi:10.1038/s41556-021-00692-z · Cited by 91 · see citing works

Structural basis for RNA polymerase II ubiquitylation and inactivation in transcription-coupled repair

Kokić, G., Yakoub, G., van den Heuvel, D., Wondergem, A. P., van der Meer, P. J., van der Weegen, Y., Chernev, A., Fianu, I., Fokkens, T. J., Lorenz, S., et al. (2024) · Nature Structural & Molecular Biology · doi:10.1038/s41594-023-01207-0 · Cited by 54 · see citing works

The molecular basis of human transcription-coupled DNA repair

van der Meer, P. J., & Luijsterburg, M. S. (2025) · Nature Cell Biology · doi:10.1038/s41556-025-01715-9 · Cited by 17 · see citing works

The ELOF(1)ant in the room of TCR

Carnie, C. J., & Jackson, S. P. (2021) · Nature Cell Biology · doi:10.1038/s41556-021-00698-7 · Cited by 6 · see citing works