Mueller, Steffen

Virus attenuation by genome-scale changes in codon pair bias

Coleman, J. R., Papamichail, D., Skiena, S., Futcher, B., Wimmer, E., & Mueller, S. (2008) · Science

RNA and protein synthesis mechanismsEvolution and Genetic Dynamics

Cited by 715

Live attenuated influenza virus vaccines by computer-aided rational design

Mueller, S., Coleman, J. R., Papamichail, D., Ward, C. B., Nimnual, A., Futcher, B., Skiena, S., & Wimmer, E. (2010) · Nature Biotechnology

Influenza Virus Research StudiesRNA and protein synthesis mechanisms

Cited by 275

Direct Interaction between Two Viral Proteins, the Nonstructural Protein 2CATPase and the Capsid Protein VP3, Is Required for Enterovirus Morphogenesis

Liu, Y., Wang, C., Mueller, S., Paul, A. V., Wimmer, E., & Jiang, P. (2010) · PLoS Pathogens

Viral Infections and Immunology ResearchEvolution and Genetic Dynamics

Cited by 142

Poliovirus and poliomyelitis: A tale of guts, brains, and an accidental event

Mueller, S., Wimmer, E., & Cello, J. (2005) · Virus Research

Viral Infections and Immunology ResearchVirology and Viral Diseases

Cited by 133

Deliberate reduction of hemagglutinin and neuraminidase expression of influenza virus leads to an ultraprotective live vaccine in mice

Yang, C., Skiena, S., Futcher, B., Mueller, S., & Wimmer, E. (2013) · Proceedings of the National Academy of Sciences

Influenza Virus Research StudiesVirology and Viral Diseases

Cited by 103

Large-scale recoding of an arbovirus genome to rebalance its insect versus mammalian preference

Shen, S. H., Stauft, C. B., Gorbatsevych, O., Song, Y., Ward, C. B., Yurovsky, A., Mueller, S., Futcher, B., & Wimmer, E. (2015) · Proceedings of the National Academy of Sciences

Mosquito-borne diseases and controlRNA and protein synthesis mechanisms

Cited by 99

Complexes of poliovirus serotypes with their common cellular receptor, CD155

He, Y., Mueller, S., Chipman, P. R., Bator, C. M., Peng, X., Bowman, V. D., Mukhopadhyay, S., Wimmer, E., Kuhn, R. J., & Rossmann, M. G. (2003) · Journal of Virology

Viral Infections and Immunology ResearchEnzyme Structure and Function

Cited by 98

Recruitment of Nectin-3 to Cell-Cell Junctions through trans-Heterophilic Interaction with CD155, a Vitronectin and Poliovirus Receptor That Localizes to αvβ3 Integrin-containing Membrane Microdomains

Mueller, S., & Wimmer, E. (2003) · Journal of Biological Chemistry

Cell Adhesion Molecules ResearchSkin and Cellular Biology Research

Cited by 90

Evaluation of the attenuation, immunogenicity, and efficacy of a live virus vaccine generated by codon-pair bias de-optimization of the 2009 pandemic H1N1 influenza virus, in ferrets

Broadbent, A. J., Santos, C. P., Anafu, A., Wimmer, E., Mueller, S., & Subbarao, K. (2016) · Vaccine

Influenza Virus Research StudiesVirology and Viral Diseases

Cited by 79

Reply to Simmonds et al.: Codon pair and dinucleotide bias have not been functionally distinguished

Futcher, B., Gorbatsevych, O., Shen, S. H., Stauft, C. B., Song, Y., Wang, B., Leatherwood, J., Gardin, J., Yurovsky, A., Mueller, S., et al. (2015) · Proceedings of the National Academy of Sciences

RNA and protein synthesis mechanismsGenomics and Phylogenetic Studies

Cited by 22