Recruitment of Nectin-3 to Cell-Cell Junctions through trans-Heterophilic Interaction with CD155, a Vitronectin and Poliovirus Receptor That Localizes to αvβ3 Integrin-containing Membrane Microdomains
Open accessAbstract
Nectins present a novel class of Ig superfamily adhesion molecules that, cooperatively with cadherins, establish and maintain cell-cell adherens junctions. CD155, the cognate receptor for poliovirus, undergoes cell-matrix contacts by binding to the extracellular matrix protein vitronectin. The significant homology of nectins with CD155 prompted us to investigate the possibility of their interaction. We determined that nectin-3 binds CD155 and its putative mouse homologue Tage4 in cell-based ligand binding assays. Coculture of nectin-3- and CD155-expressing HeLa cells led to CD155-dependent recruitment of nectin-3 to cell-cell contacts. In a heterologous coculture system with CD155 expressing mouse neuroblastoma cells, HeLa cell-expressed nectin-3 was recruited to contact sites with CD155 bearing neurites. CD155 and nectin-3 colocalized to epithelial cell-cell junctions in renal proximal tubules and in the amniotic membrane. Efficient interaction depended on CD155 dimerization, which appears to be aided by cell type-specific cofactors. We furthermore found CD155 to codistribute with alpha(v) integrin microdomains on the surface of transfected mouse fibroblasts and at amniotic epithelial cell junctions. Our findings demonstrate the possible trans-interaction between the bona fide cell-cell adherens type adhesion system (cadherin/nectin) and the cell-matrix adhesion system (integrin/CD155) by virtue of their nectin-3 and CD155 components, respectively.
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Substitutions in the IRES contribute most to the attenuated phenotype of the Sabin 1 and Sabin 3 strains.
“The substitutions in the IRES, which alter stem-loop structures (63, 68, 126, 132) and reduce the efficiency of initiation of translation of the poliovirus RNA template (68, 188), contribute most to the attenuated phenotype of the Sabin 1 and Sabin 3 strains.”
From VACCINE-DERIVED POLIOVIRUSES AND THE ENDGAME STRATEGY FOR GLOBAL POLIO ERADICATION (2005) · cites this paper as [132]
Mutations that restore the original stem-loop structure in the IRES are frequently found in vaccine-related isolates from healthy OPV recipients, patients with VAPP, and the environment.
“Mutations that restore the original stem-loop structure in the IRES [Sabin 1: G480A (backmutation) or U525C (suppressor); Sabin 2: A481G;Sabin3:U472C]arefrequentlyfound in vaccine-related isolates from healthy OPV recipients (127, 132) and patients with VAPP (61), as well as from the environment (228).”
From VACCINE-DERIVED POLIOVIRUSES AND THE ENDGAME STRATEGY FOR GLOBAL POLIO ERADICATION (2005) · cites this paper as [132]
Cites
Integrins: Versatility, modulation, and signaling in cell adhesion
Hynes, R. O. (1992) · Cell · doi:10.1016/0092-8674(92)90115-s · Cited by 9,857 · see citing works
FOCAL ADHESIONS, CONTRACTILITY, AND SIGNALING
Burridge, K., & Chrzanowska‐Wodnicka, M. (1996) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.12.1.463 · Cited by 1,943 · see citing works
Adhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the αEβ7 integrin
Cepek, K. L., Shaw, S. K., Parker, C. M., Russell, G. J., Morrow, J. S., Rimm, D. L., & Brenner, M. B. (1994) · Nature · doi:10.1038/372190a0 · Cited by 1,178 · see citing works
Mendelsohn, C. L., Wimmer, E., & Racaniello, V. R. (1989) · Cell · doi:10.1016/0092-8674(89)90690-9 · Cited by 1,116 · see citing works
Self-citationAplin, A. E., Howe, A. K., Alahari, S. K., & Juliano, R. L. (1998) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01359-0 · Cited by 847 · see citing works
The kit ligand: A cell surface molecule altered in steel mutant fibroblasts
Flanagan, J. G., & Leder, P. (1990) · Cell · doi:10.1016/0092-8674(90)90299-t · Cited by 770 · see citing works
Cheng, H.-J., Nakamoto, M., Bergemann, A. D., & Flanagan, J. G. (1995) · Cell · doi:10.1016/0092-8674(95)90426-3 · Cited by 738 · see citing works
Berger, J., Hauber, J., Hauber, R., Geiger, R. E., & Cullen, B. R. (1988) · Gene · doi:10.1016/0378-1119(88)90219-3 · Cited by 667 · see citing works
Sonnenberg, A., Calafat, J., Janssen, H., Daams, H., van der Raaij-Helmer, L., Falcioni, R., Kennel, S. J., Aplin, J., Baker, J. E., & Loizidou, M. (1991) · The Journal of Cell Biology · doi:10.1083/jcb.113.4.907 · Cited by 570 · see citing works
Takahashi, K., Nakanishi, H., Miyahara, M., Mandai, K., Satoh, K., Satoh, A., Nishioka, H., Aoki, J., Nomoto, A., Mizoguchi, A., et al. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.145.3.539 · Cited by 540 · see citing works
Alpha 6 beta 4 integrin heterodimer is a component of hemidesmosomes.
Stepp, M. A., Spurr-Michaud, S. J., Tisdale, A. S., Elwell, J., & Gipson, I. K. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.22.8970 · Cited by 483 · see citing works
Gladson, C. L., & Cheresh, D. A. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115516 · Cited by 420 · see citing works
Transgenic mice expressing a human poliovirus receptor: A new model for poliomyelitis
Ren, R., Costantini, F. D., Gorgacz, E. J., Lee, J. J., & Racaniello, V. R. (1990) · Cell · doi:10.1016/0092-8674(90)90168-e · Cited by 379 · see citing works
Intergeneric poliovirus recombinants for the treatment of malignant glioma
Gromeier, M., Lachmann, S., Rosenfeld, M. R., Gutin, P. H., & Wimmer, E. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.12.6803 · Cited by 363 · see citing works
Self-citationReymond, N., Fabre, S., Lecocq, E., Adélaı̈de, J., Dubreuil, P. C., & Lopez, M. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m103810200 · Cited by 331 · see citing works
The poliovirus receptor protein is produced both as membrane‐bound and secreted forms.
Koike, S., Horie, H., Ise, I., Okitsu, A., Yoshida, M., Iizuka, N., Takeuchi, K., Takegami, T., & Nomoto, A. (1990) · The EMBO Journal · doi:10.1002/j.1460-2075.1990.tb07520.x · Cited by 321 · see citing works
Transgenic mice susceptible to poliovirus.
Koike, S., Taya, C., Kurata, T., Abe, S., Ise, I., Yonekawa, H., & Nomoto, A. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.3.951 · Cited by 294 · see citing works
Mizoguchi, A., Nakanishi, H., Kimura, K., Matsubara, K., Kuroda, K. O., Katata, T., Honda, T., Kiyohara, Y., Heo, K., Higashi, M., et al. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200103113 · Cited by 289 · see citing works
Overexpression of the CD155 gene in human colorectal carcinoma
Masson, D., Jarry, A., Baury, B., Blanchardie, P., LABOISSE, C. L., LUSTENBERGER, P., & Denis, M. G. (2001) · Gut · doi:10.1136/gut.49.2.236 · Cited by 285 · see citing works
Satoh-Horikawa, K., Nakanishi, H., Takahashi, K. P., Miyahara, M., Nishimura, M., Tachibana, K., Mizoguchi, A., & Takai, Y. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.14.10291 · Cited by 283 · see citing works
Tachibana, K., Nakanishi, H., Mandai, K., Ozaki, K., Ikeda, W., Yamamoto, Y., Nagafuchi, A., Tsukita, S., & Takai, Y. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.150.5.1161 · Cited by 272 · see citing works
Nectin Couples Cell-Cell Adhesion and the Actin Scaffold at Heterotypic Testicular Junctions
Kuroda, K. O., Nakanishi, H., Ohta, H., Tanaka, H., Kurihara, H., Mueller, S., Irie, K., Ikeda, W., Sakai, T., Wimmer, E., et al. (2002) · Current Biology · doi:10.1016/s0960-9822(02)00922-3 · Cited by 247 · see citing works
Self-citationInteraction of the poliovirus receptor with poliovirus
He, Y., Bowman, V. D., Mueller, S., Bator, C. M., Bella, J., Peng, X., Baker, T. S., Wimmer, E., Kuhn, R. J., & Rossmann, M. G. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.1.79 · Cited by 243 · see citing works
Self-citationBiology and function of hemidesmosomes
Nievers, M. G., Schaapveld, R. Q. J., & Sonnenberg, A. (1999) · Matrix Biology · doi:10.1016/s0945-053x(98)00003-1 · Cited by 211 · see citing works
Roivainen, M., Piirainen, L., Hovi, T., Virtanen, I., Riikonen, T., Heino, J., & Hyypiä, T. (1994) · Virology · doi:10.1006/viro.1994.1494 · Cited by 210 · see citing works
Eberlé, F., Dubreuil, P. C., Mattéi, M., Devilard, É., & Lopez, M. (1995) · Gene · doi:10.1016/0378-1119(95)00180-e · Cited by 183 · see citing works
Lopez, M., Aoubala, M., Jordier, F., Isnardon, D., Gomez, S., & Dubreuil, P. C. (1998) · Blood · doi:10.1182/blood.v92.12.4602 · Cited by 165 · see citing works
Lopez, M., Eberlé, F., Mattéi, M., Gabert, J. A., Birg, F., Bardin, F., Maroc, C., & Dubreuil, P. C. (1995) · Gene · doi:10.1016/0378-1119(94)00842-g · Cited by 162 · see citing works
Miyahara, M., Nakanishi, H., Takahashi, K. P., Satoh-Horikawa, K., Tachibana, K., & Takai, Y. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.1.613 · Cited by 154 · see citing works
Mueller, S., Cao, X., Welker, R., & Wimmer, E. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m111937200 · Cited by 144 · see citing works
Self-citationMolecular cloning and expression of a murine homolog of the human poliovirus receptor gene
Morrison, M. E., & Racaniello, V. R. (1992) · Journal of Virology · doi:10.1128/jvi.66.5.2807-2813.1992 · Cited by 143 · see citing works
Human poliovirus receptor gene expression and poliovirus tissue tropism in transgenic mice
Ren, R., & Racaniello, V. R. (1992) · Journal of Virology · doi:10.1128/jvi.66.1.296-304.1992 · Cited by 142 · see citing works
Cerebral microenvironment influences expression of the vitronectin gene in astrocytic tumors
Gladson, C. L., Wilcox, J. N., Sanders, L. C., Gillespie, G. Y., & Cheresh, D. A. (1995) · Journal of Cell Science · doi:10.1242/jcs.108.3.947 · Cited by 136 · see citing works
Ikeda, W., Kakunaga, S., Itoh, S., Shingai, T., Takekuni, K., Satoh, K., Inoue, Y., Hamaguchi, A., Morimoto, K., Takeuchi, M., et al. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m303586200 · Cited by 131 · see citing works
Iwasaki, A., Welker, R., Mueller, S., Linehan, M. M., Nomoto, A., & Wimmer, E. (2002) · The Journal of Infectious Diseases · doi:10.1086/342682 · Cited by 121 · see citing works
Self-citationAoki, J., Koike, S., Asou, H., Ise, I., Suwa, H., Tanaka, T. T., Miyasaka, M., & Nomoto, A. (1997) · Experimental Cell Research · doi:10.1006/excr.1997.3685 · Cited by 119 · see citing works
Yang, W., Terasaki, T., Shiroki, K., Ohka, S., Aoki, J., Tanabe, S., Nomura, T., Terada, E., Sugiyama, Y., & Nomoto, A. (1997) · Virology · doi:10.1006/viro.1997.8450 · Cited by 115 · see citing works
Flanagan, J. G., Cheng, H.-J., Feldheim, D. A., Hattori, M., Lü, Q., & Vanderhaeghen, P. (2000) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(00)27264-9 · Cited by 113 · see citing works
ADIP, a Novel Afadin- and α-Actinin-Binding Protein Localized at Cell-Cell Adherens Junctions
Asada, M., Irie, K., Morimoto, K., Yamada, A., Ikeda, W., Takeuchi, M., & Takai, Y. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m209832200 · Cited by 106 · see citing works
Basement membrane invasion of glioma cells mediated by integrin receptors
Paulus, W., & Tonn, J. C. (1994) · Journal of neurosurgery · doi:10.3171/jns.1994.80.3.0515 · Cited by 101 · see citing works
Honda, T., Shimizu, K., Kawakatsu, T., Yasumi, M., Shingai, T., Fukuhara, A., Kuroda, K. O., Irie, K., Nakanishi, H., & Takai, Y. (2003) · Genes to Cells · doi:10.1046/j.1365-2443.2003.00616.x · Cited by 96 · see citing works
Lange, R., Peng, X., Wimmer, E., Lipp, M., & Bernhardt, G. (2001) · Virology · doi:10.1006/viro.2001.0943 · Cited by 96 · see citing works
Self-citationNobis, P., Zibirre, R., Meyer, G., Kuhne, J., Warnecke, G., & Koch, G. (1985) · Journal of General Virology · doi:10.1099/0022-1317-66-12-2563 · Cited by 88 · see citing works
Amino acid residues on human poliovirus receptor involved in interaction with poliovirus.
Aoki, J., Koike, S., Ise, I., Sato-Yoshida, Y., & Nomoto, A. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)37212-5 · Cited by 85 · see citing works
Fechner, H., Wang, X., Wang, H., Jansen, A., Pauschinger, M., Scherübl, H., Bergelson, J. M., Schultheiss, H.-P., & Poller, W. C. (2000) · Gene Therapy · doi:10.1038/sj.gt.3301321 · Cited by 85 · see citing works
Expression of the Human Poliovirus Receptor/CD155 Gene Is Activated by Sonic Hedgehog
Solecki, D. J., Gromeier, M., Mueller, S., Bernhardt, G., & Wimmer, E. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m201378200 · Cited by 81 · see citing works
Self-citationA novel member of the immunoglobulin gene superfamily expressed in rat carcinoma cell lines.
Chadéneau, C., LeMoullac, B., & Denis, M. G. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)40723-x · Cited by 75 · see citing works
E-cadherin is a ligand for integrin α2β1
Whittard, J. D., Craig, S. E., Mould, A. P., Koch, A., Pertz, O. C., Engel, J., & Humphries, M. J. (2002) · Matrix Biology · doi:10.1016/s0945-053x(02)00037-9 · Cited by 63 · see citing works
Role of the second immunoglobulin-like loop of nectin in cell–cell adhesion
Momose, Y., Honda, T., Inagaki, M., Shimizu, K., Irie, K., Nakanishi, H., & Takai, Y. (2002) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(02)00183-3 · Cited by 52 · see citing works
Ohka, S., Ohno, H., Tohyama, K., & Nomoto, A. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.5660 · Cited by 36 · see citing works
Arita, M., Horie, H., Arita, M., & Nomoto, A. (1999) · Journal of Virology · doi:10.1128/jvi.73.2.1066-1074.1999 · Cited by 29 · see citing works
Prevalence of Human Papillomavirus Infection Among Prostitutes in Calcutta
Chatterjee, R., Mukhopadhyay, D., Murmu, N., & Jana, S. (2001) · Journal of Environmental Pathology Toxicology and Oncology · doi:10.1615/jenvironpatholtoxicoloncol.v20.i2.50 · Cited by 28 · see citing works
Bidirectional entry of poliovirus into polarized epithelial cells
Tucker, S. P., Thornton, C. L., Wimmer, E., & Compans, R. W. (1993) · Journal of Virology · doi:10.1128/jvi.67.1.29-38.1993 · Cited by 27 · see citing works
Self-citationRole of anb3 Integrin Receptor in the Invasive Potential of Human Cervical Cancer (SiHa) Cells
Chattopadhyay, N., & Chatterjee, A. (2001) · Journal of Environmental Pathology Toxicology and Oncology · doi:10.1615/jenvironpatholtoxicoloncol.v20.i3.50 · Cited by 25 · see citing works
Viruses for the treatment of malignant glioma.
Gromeier, M., & Wimmer, E. (2001) · PubMed · Cited by 24 · see citing works
Self-citationOrganization of the rat Tage4 gene and herpesvirus entry activity of the encoded protein
Baury, B., Geraghty, R. J., Masson, D., LUSTENBERGER, P., Spear, P. G., & Denis, M. G. (2001) · Gene · doi:10.1016/s0378-1119(01)00343-2 · Cited by 24 · see citing works
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Kew, O. M., Sutter, R. W., de Gourville, E. M., Dowdle, W. R., & Pallansch, M. A. (2005) · Annual Review of Microbiology · doi:10.1146/annurev.micro.58.030603.123625 · Cited by 703 · see citing works
Balancing natural killer cell activation through paired receptors
Martinet, L., & Smyth, M. J. (2015) · Nature reviews. Immunology · doi:10.1038/nri3799 · Cited by 483 · see citing works
Nectins and nectin‐like molecules: Roles in cell adhesion, migration, and polarization
Takai, Y., Irie, K., Shimizu, K., Sakisaka, T., & Ikeda, W. (2003) · Cancer Science · doi:10.1111/j.1349-7006.2003.tb01499.x · Cited by 375 · see citing works
One hundred years of poliovirus pathogenesis
Racaniello, V. R. (2006) · Virology · doi:10.1016/j.virol.2005.09.015 · Cited by 322 · see citing works
CD155/PVR plays a key role in cell motility during tumor cell invasion and migration
Sloan, K. E., Eustace, B. K., Stewart, J. K., Zehetmeier, C., Torella, C., Simeone, M., Roy, J. E., Unger, C., Louis, D. N., Ilag, L. L., et al. (2004) · BMC Cancer · doi:10.1186/1471-2407-4-73 · Cited by 244 · see citing works
Stengel, K. F., Bowles, K. H., Yu, X., Rougé, L., Yin, J., Comps‐Agrar, L., Wiesmann, C., Bazán, J. F., Eaton, D., & Grogan, J. L. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1120606109 · Cited by 216 · see citing works
CD 155, an onco‐immunologic molecule in human tumors
Gao, J., Zheng, Q., Xin, N., Wang, W., & Zhao, C. (2017) · Cancer Science · doi:10.1111/cas.13324 · Cited by 199 · see citing works
Tumor intrinsic and extrinsic immune functions of CD155
O’Donnell, J. S., Madore, J., Li, X.-Y., & Smyth, M. J. (2019) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2019.11.013 · Cited by 136 · see citing works
Overexpression of Necl‐5 correlates with unfavorable prognosis in patients with lung adenocarcinoma
Nakai, R., Maniwa, Y., Tanaka, Y., Nishio, W., Yoshimura, M., Okita, Y., Ohbayashi, C., Satoh, N., Ogita, H., Takai, Y., et al. (2010) · Cancer Science · doi:10.1111/j.1349-7006.2010.01530.x · Cited by 134 · see citing works
Poliovirus and poliomyelitis: A tale of guts, brains, and an accidental event
Mueller, S., Wimmer, E., & Cello, J. (2005) · Virus Research · doi:10.1016/j.virusres.2005.04.008 · Cited by 133 · see citing works
Self-citationBiology and pathology of nectins and nectin-like molecules
Sakisaka, T., & Takai, Y. (2004) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2004.07.007 · Cited by 131 · see citing works
Vitronectin—Master controller or micromanager?
Leavesley, D. I., Kashyap, A. S., Croll, T. I., Sivaramakrishnan, M., Shokoohmand, A., Hollier, B. G., & Upton, Z. (2013) · IUBMB Life · doi:10.1002/iub.1203 · Cited by 126 · see citing works
Mueller, S. (2003) · Biology of Reproduction · doi:10.1095/biolreprod.102.014670 · Cited by 127 · see citing works
Self-citationNectin ectodomain structures reveal a canonical adhesive interface
Harrison, O. J., Vendôme, J., Brasch, J., Jin, X., Hong, S., Katsamba, P. S., Ahlsén, G., Troyanovsky, R. B., Troyanovsky, S. M., Honig, B. H., et al. (2012) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2366 · Cited by 126 · see citing works
Coming of Age: CD96 Emerges as Modulator of Immune Responses
Georgiev, H., Ravens, I., Papadogianni, G., & Bernhardt, G. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.01072 · Cited by 115 · see citing works
CD155: A Multi-Functional Molecule in Tumor Progression
Molfetta, R., Zitti, B., Lecce, M., Milito, N. D., Stabile, H., Fionda, C., Cippitelli, M., Gismondi, A., Santoni, A., & Paolini, R. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21030922 · Cited by 113 · see citing works
Kakunaga, S., Ikeda, W., Shingai, T., Fujito, T., Yamada, A., Minami, Y., Imai, T., & Takai, Y. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m406340200 · Cited by 115 · see citing works
CD155 immunoregulation as a target for natural killer cell immunotherapy in glioblastoma
Lupo, K. B., & Matosevic, S. (2020) · Journal of Hematology & Oncology · doi:10.1186/s13045-020-00913-2 · Cited by 108 · see citing works
Roles and modes of action of nectins in cell–cell adhesion
Irie, K., Shimizu, K., Sakisaka, T., Ikeda, W., & Takai, Y. (2004) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2004.09.002 · Cited by 109 · see citing works
Ikeda, W., Kakunaga, S., Takekuni, K., Shingai, T., Satoh, K., Morimoto, K., Takeuchi, M., Imai, T., & Takai, Y. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m312969200 · Cited by 108 · see citing works
Fujito, T., Ikeda, W., Kakunaga, S., Minami, Y., Kajita, M., Sakamoto, Y., Monden, M., & Takai, Y. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200501090 · Cited by 107 · see citing works
The murine pan T cell marker CD96 is an adhesion receptor for CD155 and nectin-1
Seth, S., Maier, M. K., Qiu, Q., Ravens, I., Kremmer, E., Förster, R., & Bernhardt, G. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.10.102 · Cited by 99 · see citing works
Xu, Z., & Jin, B. (2010) · Cellular and Molecular Immunology · doi:10.1038/cmi.2009.108 · Cited by 91 · see citing works
Crystal structure of CD155 and electron microscopic studies of its complexes with polioviruses
Zhang, P., Mueller, S., Morais, M. C., Bator, C. M., Bowman, V. D., Hafenstein, S. L., Wimmer, E., & Rossmann, M. G. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0807848105 · Cited by 90 · see citing works
Self-citationInteraction of Integrin αvβ3 with Nectin
Sakamoto, Y., Ogita, H., Hirota, T., Kawakatsu, T., Fukuyama, T., Yasumi, M., Kanzaki, N., Ozaki, M., & Takai, Y. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m600301200 · Cited by 86 · see citing works
Roles of nectins in cell adhesion, migration and polarization
Nakanishi, H., & Takai, Y. (2004) · Biological Chemistry · doi:10.1515/bc.2004.116 · Cited by 85 · see citing works
CD 155 knockdown promotes apoptosis via AKT /Bcl‐2/Bax in colon cancer cells
Zheng, Q., Wang, B., Gao, J., Xin, N., Wang, W., Song, X., Shao, Y., & Zhao, C. (2017) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.13301 · Cited by 80 · see citing works
Hirota, T., Irie, K., Okamoto, R., Ikeda, W., & Takai, Y. (2005) · Oncogene · doi:10.1038/sj.onc.1208409 · Cited by 79 · see citing works
Maier, M. K., Seth, S., Czeloth, N., Qiu, Q., Ravens, I., Kremmer, E., Ebel, M., Müller, W., Pabst, O., Förster, R., et al. (2007) · European Journal of Immunology · doi:10.1002/eji.200737072 · Cited by 76 · see citing works
Ligand stimulation of CD155α inhibits cell adhesion and enhances cell migration in fibroblasts
Oda, T., Ohka, S., & Nomoto, A. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.05.111 · Cited by 72 · see citing works
Toyoda, H., Yin, J., Mueller, S., Wimmer, E., & Cello, J. (2007) · Cancer Research · doi:10.1158/0008-5472.can-06-3713 · Cited by 72 · see citing works
Self-citationCarter, C. (2017) · Journal of Alzheimer s Disease Reports · doi:10.3233/adr-170017 · Cited by 70 · see citing works
Nectin and Nectin-Like Molecules: Biology and Pathology
Miyoshi, J., & Takai, Y. (2007) · American Journal of Nephrology · doi:10.1159/000108103 · Cited by 66 · see citing works
Poliovirus Receptor (CD155) Regulates a Step in Transendothelial Migration between PECAM and CD99
Sullivan, D. P., Seidman, M. A., & Müller, W. A. (2013) · American Journal Of Pathology · doi:10.1016/j.ajpath.2012.11.037 · Cited by 64 · see citing works
Neutrophil and monocyte recruitment by PECAM, CD99, and other molecules via the LBRC
Sullivan, D. P., & Müller, W. A. (2013) · Seminars in Immunopathology · doi:10.1007/s00281-013-0412-6 · Cited by 62 · see citing works
Leukocyte transmigration across the blood-brain barrier: perspectives on neuroAIDS
Roberts, T. K. (2009) · Frontiers in bioscience · doi:10.2741/3631 · Cited by 56 · see citing works
Seth, S., Georgoudaki, A., Chambers, B. J., Qiu, Q., Kremmer, E., Maier, M. K., Czeloth, N., Ravens, I., Foerster, R., & Bernhardt, G. (2009) · Journal of Leukocyte Biology · doi:10.1189/jlb.1208745 · Cited by 51 · see citing works
Update in TIGIT Immune-Checkpoint Role in Cancer
Annese, T., Tamma, R., & Ribatti, D. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.871085 · Cited by 50 · see citing works
Umemoto, T., Yamato, M., Shiratsuchi, Y., Terasawa, M., Yang, J., Nishida, K., Kobayashi, Y., & Okano, T. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.11.7733 · Cited by 46 · see citing works
Ravens, I., Seth, S., Förster, R., & Bernhardt, G. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2003.11.067 · Cited by 46 · see citing works
Ogita, H., & Takai, Y. (2008) · International review of cytology · doi:10.1016/s0074-7696(07)65001-3 · Cited by 45 · see citing works
CD155 in tumor progression and targeted therapy
Zhan, M., Zhang, Z., Zhao, X., Zhang, Y., Liu, T., Lu, L., & Li, X.-Y. (2022) · Cancer Letters · doi:10.1016/j.canlet.2022.215830 · Cited by 44 · see citing works
The CD155/poliovirus receptor enhances the proliferation of ras‐mutated cells
Kono, T., Imai, Y., Yasuda, S., Ohmori, K., Fukui, H., Ichikawa, K., Tomita, S., Imura, J., Kuroda, Y., Ueda, Y., et al. (2007) · International Journal of Cancer · doi:10.1002/ijc.23080 · Cited by 44 · see citing works
Abundance of follicular helper T cells in Peyer's patches is modulated by CD155
Seth, S., Ravens, I., Kremmer, E., Maier, M. K., Hadis, U., Hardtke, S., Förster, R., & Bernhardt, G. (2009) · European Journal of Immunology · doi:10.1002/eji.200939470 · Cited by 36 · see citing works
Erickson, B. M., Thompson, N. L., & Hixson, D. C. (2006) · Hepatology · doi:10.1002/hep.21021 · Cited by 36 · see citing works
Expression patterns of nectins and afadin during epithelial remodeling in the mouse embryo
Okabe, N., Ozaki‐Kuroda, K., Nakanishi, H., Shimizu, K., & Takai, Y. (2004) · Developmental Dynamics · doi:10.1002/dvdy.20033 · Cited by 35 · see citing works
CD155 downregulation synergizes with adriamycin to induce breast cancer cell apoptosis
Gao, J., Zheng, Q., Shao, Y., Wang, W., & Zhao, C. (2018) · APOPTOSIS · doi:10.1007/s10495-018-1473-8 · Cited by 33 · see citing works
Rikitake, Y., & Takai, Y. (2007) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-007-7290-9 · Cited by 33 · see citing works
Virus interaction with the apical junctional complex
González‐Mariscal, L. (2009) · Frontiers in bioscience · doi:10.2741/3276 · Cited by 32 · see citing works
CD155 contributes to the mesenchymal phenotype of triple‐negative breast cancer
Zheng, Q., Gao, J., Yin, P., Wang, W., Wang, B., Li, Y., & Zhao, C. (2019) · Cancer Science · doi:10.1111/cas.14276 · Cited by 32 · see citing works
Roles of Nectins and Nectin-Like Molecules in the Nervous System
Mori, M., Rikitake, Y., Mandai, K., & Takai, Y. (2013) · Advances in neurobiology · doi:10.1007/978-1-4614-8090-7_5 · Cited by 31 · see citing works
Poliovirus, Pathogenesis of Poliomyelitis, and Apoptosis
Blondel, B., Colbère-Garapin, F., Couderc, T., Wirotius, A., & Guivel‐Benhassine, F. (2005) · Springer eBooks · doi:10.1007/3-540-27320-4_2 · Cited by 32 · see citing works
CD155 and Its Receptors as Targets for Cancer Therapy
Paolini, R., & Molfetta, R. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241612958 · Cited by 30 · see citing works
Yap, E.-H., Rosche, T., Almo, S. C., & Fiser, A. (2013) · Journal of Molecular Biology · doi:10.1016/j.jmb.2013.11.009 · Cited by 27 · see citing works
Ogita, H., Ikeda, W., & TAKAI, Y. (2008) · Journal of Microscopy · doi:10.1111/j.1365-2818.2008.02058.x · Cited by 27 · see citing works
Sato, T., Irie, K., Ooshio, T., Ikeda, W., & Takai, Y. (2004) · Genes to Cells · doi:10.1111/j.1365-2443.2004.00763.x · Cited by 27 · see citing works
CRTAM: A molecule involved in epithelial cell adhesion
Garay, E., Patiño‐López, G., Islas, S., Alarcón, L., Canché-Pool, E. B., Valle‐Rios, R., Contreras, O. M., Granados, G., Chávez‐Munguía, B., Juaristi, E., et al. (2010) · Journal of Cellular Biochemistry · doi:10.1002/jcb.22673 · Cited by 24 · see citing works
Ylipaasto, P., Eskelinen, M., Salmela, K. T., Hovi, T., & Roivainen, M. (2009) · Journal of General Virology · doi:10.1099/vir.0.012450-0 · Cited by 24 · see citing works
CD155 expression impairs anti-PD1 therapy response in non-small cell lung cancer
Jiang, C., Qu, X., Ma, L., Yi, L., Xu, C. Y., Gao, X., Wang, J., Che, N., Zhang, H., & Zhang, S. (2022) · Clinical & Experimental Immunology · doi:10.1093/cei/uxac020 · Cited by 23 · see citing works
Sato, T., Irie, K., Okamoto, R., Ooshio, T., Fujita, N., & Takai, Y. (2005) · Cancer Science · doi:10.1111/j.1349-7006.2005.00087.x · Cited by 23 · see citing works
Qiu, Q., Ravens, I., Seth, S., Rathinasamy, A., Maier, M. K., Davalos‐Misslitz, A. C. M., Förster, R., & Bernhardt, G. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0900062 · Cited by 22 · see citing works
Cancer Immunotherapy and the Nectin Family
Johnston, R. J., Lee, P. S., Strop, P., & Smyth, M. J. (2020) · Annual Review of Cancer Biology · doi:10.1146/annurev-cancerbio-060920-084910 · Cited by 19 · see citing works
Jahan, N., Wimmer, E., & Mueller, S. (2011) · Journal of Virology · doi:10.1128/jvi.01804-09 · Cited by 19 · see citing works
Self-citationCD155: A Key Receptor Playing Diversified Roles
Nandi, S. S., Gohil, T., Sawant, S. A., Lambe, U. P., Ghosh, S., & Jana, S. (2021) · Current Molecular Medicine · doi:10.2174/1566524021666210910112906 · Cited by 18 · see citing works
Danisch, S., Qiu, Q., Seth, S., Ravens, I., Dorsch, M. M., Shibuya, A., Shibuya, K., Förster, R., & Bernhardt, G. (2012) · Immunobiology · doi:10.1016/j.imbio.2012.02.010 · Cited by 18 · see citing works
Cell Adhesion Molecules of the Immunoglobulin Superfamily in the Nervous System
Walmod, P. S., Pedersen, M. V., Berezin, V., & Bock, E. (2007) · Springer eBooks · doi:10.1007/978-0-387-30379-6_2 · Cited by 15 · see citing works
Devaux, C. A., Pontarotti, P., Levasseur, A., Colson, P., & Raoult, D. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1284337 · Cited by 16 · see citing works
Yap, E.-H., & Fiser, A. (2016) · Structure · doi:10.1016/j.str.2016.10.012 · Cited by 12 · see citing works
Expression and possible role of PVR/CD155/Necl-5 in osteoclastogenesis
Kakehi, S., Nakahama, K., & Morita, I. (2007) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-007-9413-x · Cited by 12 · see citing works
Poliovirus type 1 infection of murinePRNP-knockout neuronal cells
Baj, A., Bettaccini, A. A., Nishimura, T., Onodera, T., & Toniolo, A. (2005) · Journal of NeuroVirology · doi:10.1080/13550280590952745 · Cited by 11 · see citing works
Characterization of the New World Monkey Homologues of Human Poliovirus Receptor CD155
Khan, S. A., Peng, X., Yin, J., Zhang, P., & Wimmer, E. (2008) · Journal of Virology · doi:10.1128/jvi.02664-07 · Cited by 9 · see citing works
Self-citationSensitivity of C6 Glioma Cells Carrying the Human Poliovirus Receptor to Oncolytic Polioviruses
Sosnovtseva, A. O., Lipatova, A. V., Grinenko, N. F., Baklaushev, V. P., Chumakov, P. M., & Chekhonin, V. P. (2016) · Bulletin of Experimental Biology and Medicine · doi:10.1007/s10517-016-3520-1 · Cited by 9 · see citing works
Suzuki, Y. (2006) · Gene · doi:10.1016/j.gene.2005.12.016 · Cited by 8 · see citing works
Kim, E. Y., & Dryer, S. E. (2024) · Cells · doi:10.3390/cells13020172 · Cited by 7 · see citing works
Nandi, S. S., Sharma, D. K., & Deshpande, J. M. (2016) · The Indian Journal of Medical Research · doi:10.4103/0971-5916.193281 · Cited by 5 · see citing works
Synthesis and QSAR Analysis of Diaryl Ethers and Their Analogues as Potential Antiviral Agents
Nikolova, I., Slavchev, I., Zagranyarska, I., Nikolova, N., Vilhelmova-Ilieva, N., Stoyanova, A., Grozdanov, P., Mukova, L., Galabov, A. S., Lessigiarska, I., et al. (2022) · ChemistrySelect · doi:10.1002/slct.202203088 · Cited by 4 · see citing works
van Houts, E. (2011) · Cambridge University Press eBooks · doi:10.1017/cbo9780511976056.019 · Cited by 4 · see citing works
Racaniello, V. R. (2016) · Springer eBooks · doi:10.1007/978-3-319-33133-1_1 · Cited by 2 · see citing works
Racaniello, V. R. (2008) · Cambridge University Press eBooks · doi:10.1017/cbo9780511541728.004 · Cited by 2 · see citing works
Recent Advances, Challenges, and Opportunities in Synthetic Genomes
Singh, V. (2020) · Springer eBooks · doi:10.1007/978-981-15-0081-7_13 · Cited by 2 · see citing works
Gordon, S. R., Dimovski, S., & Kocik, N. (2022) · Experimental Eye Research · doi:10.1016/j.exer.2022.109212 · Cited by 1 · see citing works
Toyoda, H., Wimmer, E., & Cello, J. (2012) · InTech eBooks · doi:10.5772/29741
Self-citationReceptor modification as a therapeutic approach against viral diseases
Farid, R., Khan, M. H., & Rashid, H. (2012) · Bioinformation · doi:10.6026/97320630008331
Polioviruses and the Endgame Strategy for Global Polio Eradication
Kew, O. M., Sutter, R. W., de Gourville, E. M., Dowdle, W. R., & Pallansch, M. A. (2005)
Reiss, C. S. (2008) · Cambridge University Press eBooks · doi:10.1017/cbo9780511541728.003
Pasupulleti, V. K. (2012) · K-State Research Exchange (Kansas State University)
Mécanismes d'immunosurveillance NKG2D et DNAM-1 dans le carcinome hépatocellulaire
Cadoux, M. (2019) · theses.fr (ABES) · doi:10.70675/a6660468zb747z4a0czb963z900d06687ec7
- Authors
- Mueller, S., & Wimmer, E.
- Affiliations
- Stony Brook University (US)
- Corresponding author
- Wimmer, Eckard
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 2003-08
- Volume
- 278
- Issue
- 33
- Pages
- 31251-31260
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1980311792
- Cited by
- 90
- References
- 56
- Citations by year
- 2024: 2 · 2023: 1 · 2022: 5 · 2021: 1 · 2020: 4 · 2019: 3 · 2018: 2 · 2017: 3 · 2016: 4 · 2015: 1 · 2014: 2 · 2013: 6 · 2012: 6
- FWCI
- 4.51
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Biological Chemistry (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- National Institute of Allergy and Infectious Diseases (AI-39485)
- Topics
- Health Sciences › Medicine › Immunology and Allergy › Cell Adhesion Molecules Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Skin and Cellular Biology Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular Mechanics and Interactions
- Keywords
- nectin-3, CD155, integrin αvβ3, poliovirus receptor, cell-cell contact, adherens junctions, alpha v beta 3 integrin, lipid rafts, trans-interactions, epithelial cell adhesion, amniotic membrane, proximal tubule
- MeSH terms
- Nectins, Amnion, Animals, Antigens, Neoplasm, Cell Adhesion, Cell Communication, Epithelial Cells, Fibroblasts, HeLa Cells, Humans, Intercellular Junctions, Kidney, Ligands, Membrane Proteins, Neoplasm Proteins, Neuroblastoma, Receptors, Cell Surface, Receptors, Virus, Cell Adhesion Molecules, PC12 Cells, Protein Structure, Tertiary, Dimerization, COS Cells, Integrin alphaVbeta3, Mice, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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