Salvatore, Domenico

Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases

Bianco, A. C., Salvatore, D., Gereben, B., Berry, M. J., & Larsen, P. R. (2002) · Endocrine Reviews

Thyroid Disorders and TreatmentsSelenium in Biological Systems

Cited by 1,853

Deiodinases and their intricate role in thyroid hormone homeostasis

Luongo, C., Dentice, M., & Salvatore, D. (2019) · Nature Reviews Endocrinology

Thyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment

Cited by 332

Regional distribution of type 2 thyroxine deiodinase messenger ribonucleic acid in rat hypothalamus and pituitary and its regulation by thyroid hormone

Tu, H. M., Kim, S.-W., Salvatore, D., Bartha, T., Legradi, G., Larsen, P. R., & Lechan, R. M. (1997) · Endocrinology

Thyroid Disorders and TreatmentsRegulation of Appetite and Obesity

Cited by 302

Molecular biological and biochemical characterization of the human type 2 selenodeiodinase.

Salvatore, D., Bartha, T., Harney, J. W., & Larsen, P. R. (1996) · Endocrinology

Thyroid Disorders and TreatmentsSelenium in Biological Systems

Cited by 284

Activation and inactivation of thyroid hormone by deiodinases: Local action with general consequences

Gereben, B., Zeöld, A., Dentice, M., Salvatore, D., & Bianco, A. C. (2008) · Cellular and Molecular Life Sciences

Thyroid Disorders and TreatmentsSelenium in Biological Systems

Cited by 207

Type 2 iodothyronine deiodinase is highly expressed in human thyroid.

Salvatore, D., Tu, H., Harney, J. W., & Larsen, P. R. (1996) · Journal of Clinical Investigation

Thyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment

Cited by 196

DIO2 Thr92Ala Reduces Deiodinase-2 Activity and Serum-T3 Levels in Thyroid-Deficient Patients

Castagna, M. G., Dentice, M., Cantara, S., Ambrosio, R., Maino, F., Porcelli, T., Marzocchi, C., Garbi, C., Pacini, F., & Salvatore, D. (2017) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment

Cited by 151

Local impact of thyroid hormone inactivation

Dentice, M., & Salvatore, D. (2011) · Journal of Endocrinology

Thyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment

Cited by 143

Characterization of the 5′-Flanking and 5′-Untranslated Regions of the Cyclic Adenosine 3′,5′-Monophosphate-Responsive Human Type 2 Iodothyronine Deiodinase Gene1

Bartha, T., Kim, S.-W., Salvatore, D., Gereben, B., Tu, H. M., Harney, J. W., Rudas, P., & Larsen, P. R. (2000) · Endocrinology

Thyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment

Cited by 118

The human, but not rat, dio2 gene is stimulated by thyroid transcription factor-1 (TTF-1)

Gereben, B., Salvatore, D., Harney, J. W., Tu, H. M., & Larsen, P. R. (2001) · Molecular Endocrinology

Thyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment

Cited by 70

Type 3 deiodinase and consumptive hypothyroidism: a common mechanism for a rare disease

Luongo, C., Trivisano, L., Alfano, F., & Salvatore, D. (2013) · Frontiers in Endocrinology

Thyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment

Cited by 67

Pendrin is a novel in vivo downstream target gene of the TTF-1/Nkx-2.1 homeodomain transcription factor in differentiated thyroid cells

Dentice, M., Luongo, C., Elefante, A., Ambrosio, R., Salzano, S., Zannini, M., Nitsch, R., Di Lauro, R., Rossi, G., Fenzi, G., et al. (2005) · Molecular and Cellular Biology

Thyroid Disorders and TreatmentsDevelopmental Biology and Gene Regulation

Cited by 48

Consumptive Hypothyroidism Resulting from Hepatic Vascular Tumors in an Athyreotic Adult

Howard, D., La Rosa, F. G., Huang, S., Salvatore, D., Mulcahey, M., Sang-Lee, J., Wachs, M., & Klopper, J. P. (2011) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsThyroid and Parathyroid Surgery

Cited by 30

The Thyroid Hormone Inactivating Enzyme Type 3 Deiodinase is Present in Bactericidal Granules and the Cytoplasm of Human Neutrophils

van der Spek, A. H., Bloise, F. F., Tigchelaar, W., Dentice, M., Salvatore, D., van der Wel, N. N., Fliers, E., & Boelen, A. (2016) · Endocrinology

Neutrophil, Myeloperoxidase and Oxidative MechanismsThyroid Disorders and Treatments

Cited by 28

Type 2 deiodinase Thr92Ala polymorphism and aging are associated with a decreased pituitary sensitivity to thyroid hormone

Luongo, C., De Stefano, M. A., Ambrosio, R., Volpe, F., Porcelli, T., Golia, V., Bellevicine, C., Troncone, G., Masone, S., Damiano, V., et al. (2023) · Thyroid

Thyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment

Cited by 11

Deiodinases: keeping the thyroid hormone supply in balance

Salvatore, D. (2011) · Journal of Endocrinology

Thyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment

Cited by 10