Mederacke, Ingmar

Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology

Mederacke, I., Hsu, C. C., Troeger, J. S., Huebener, P., Mu, X., Dapito, D. H., Pradere, J.-P., & Schwabe, R. F. (2013) · Nature Communications

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 1,443

Promotion of Hepatocellular Carcinoma by the Intestinal Microbiota and TLR4

Dapito, D. H., Mencin, A., Gwak, G.-Y., Pradere, J.-P., Jang, M.-K., Mederacke, I., Caviglia, J. M., Khiabanian, H., Adeyemi, A., Bataller, R., et al. (2012) · Cancer Cell

Hepatocellular Carcinoma Treatment and PrognosisLiver physiology and pathology

Cited by 1,346

Hepatic macrophages but not dendritic cells contribute to liver fibrosis by promoting the survival of activated hepatic stellate cells in mice

Pradere, J.-P., Kluwe, J., De Minicis, S., Jiao, J.-J., Gwak, G.-Y., Dapito, D. H., Jang, M.-K., Guenther, N. D., Mederacke, I., Friedman, R., et al. (2013) · Hepatology

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 613

Deactivation of Hepatic Stellate Cells During Liver Fibrosis Resolution in Mice

Troeger, J. S., Mederacke, I., Gwak, G., Dapito, D. H., Mu, X., Hsu, C. C., Pradere, J., Friedman, R. A., & Schwabe, R. F. (2012) · Gastroenterology

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 515

Tumor restriction by type I collagen opposes tumor-promoting effects of cancer-associated fibroblasts

Bhattacharjee, S., Hamberger, F., Ravichandra, A., Miller, M., Nair, A., Affo, S., Filliol, A., Chin, L., Savage, T. M., Yin, D., et al. (2021) · Journal of Clinical Investigation

Cancer Cells and MetastasisCellular Mechanics and Interactions

Cited by 367

The purinergic P2Y14 receptor links hepatocyte death to hepatic stellate cell activation and fibrogenesis in the liver

Mederacke, I., Filliol, A., Affo, S., Nair, A., Hernandez, C., Sun, Q., Hamberger, F., Brundu, F., Chen, Y., Ravichandra, A., et al. (2022) · Science Translational Medicine

Adenosine and Purinergic SignalingLiver physiology and pathology

Cited by 103

High-Mobility Group Box 1 Is Dispensable for Autophagy, Mitochondrial Quality Control, and Organ Function in Vivo

Huebener, P., Gwak, G.-Y., Pradere, J.-P., Quinzii, C. M., Friedman, R., Lin, C.-S., Trent, C. M., Mederacke, I., Zhao, E., Dapito, D. H., et al. (2014) · Cell Metabolism

Autophagy in Disease and TherapyMitochondrial Function and Pathology

Cited by 86