Johnstone, Ricky W.

Anticancer activities of histone deacetylase inhibitors

Bolden, J. E., Peart, M. J., & Johnstone, R. W. (2006) · Nature Reviews Drug Discovery

Histone Deacetylase Inhibitors ResearchEpigenetics and DNA Methylation

Cited by 2,919

Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders

Falkenberg, K. J., & Johnstone, R. W. (2014) · Nature Reviews Drug Discovery

Histone Deacetylase Inhibitors ResearchEpigenetics and DNA Methylation

Cited by 1,564

Histone-deacetylase inhibitors: novel drugs for the treatment of cancer

Johnstone, R. W. (2002) · Nature Reviews Drug Discovery

Histone Deacetylase Inhibitors ResearchEpigenetics and DNA Methylation

Cited by 1,515

New and emerging HDAC inhibitors for cancer treatment

West, A. C., & Johnstone, R. W. (2014) · Journal of Clinical Investigation

Histone Deacetylase Inhibitors ResearchEpigenetics and DNA Methylation

Cited by 1,404

BET inhibitor resistance emerges from leukaemia stem cells

Fong, C. Y., Gilan, O., Lam, E. Y. N., Rubin, A. F., Ftouni, S., Tyler, D., Stanley, K., Sinha, D., Yeh, P., Morison, J., et al. (2015) · Nature

Protein Degradation and InhibitorsChromatin Remodeling and Cancer

Cited by 545

Tumor immune evasion arises through loss of TNF sensitivity

Kearney, C. J., Vervoort, S. J., Hogg, S. J., Ramsbottom, K. M., Freeman, A. J., Lalaoui, N., Pijpers, L., Michie, J., Brown, K. K., Knight, D. A., et al. (2018) · Science Immunology

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 381

BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1

Hogg, S. J., Vervoort, S. J., Deswal, S., Ott, C. J., Li, J., Cluse, L. A., Beavis, P. A., Darcy, P. K., Martin, B. P., Spencer, A., et al. (2017) · Cell Reports

Protein Degradation and InhibitorsCancer Immunotherapy and Biomarkers

Cited by 308

Epigenetic changes to the MDR1 locus in response to chemotherapeutic drugs

Baker, E. K., Johnstone, R. W., Zalcberg, J. R., & El-Osta, A. (2005) · Oncogene

Drug Transport and Resistance MechanismsEpigenetics and DNA Methylation

Cited by 196

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition

Hogg, S. J., Motorna, O., Cluse, L. A., Johanson, T. M., Coughlan, H. D., Raviram, R., Myers, R. M., Costacurta, M., Todorovski, I., Pijpers, L., et al. (2021) · Molecular Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 170

CDK13 cooperates with CDK12 to control global RNA polymerase II processivity

Fan, Z., Devlin, J. R., Hogg, S. J., Doyle, M. A., Harrison, P. F., Todorovski, I., Cluse, L. A., Knight, D. A., Sandow, J. J., Gregory, G., et al. (2020) · Science Advances

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 164

An intact immune system is required for the anticancer activities of histone deacetylase inhibitors

West, A. C., Mattarollo, S. R., Shortt, J., Cluse, L. A., Christiansen, A. J., Smyth, M. J., & Johnstone, R. W. (2013) · Cancer Research

Histone Deacetylase Inhibitors ResearchImmunotherapy and Immune Responses

Cited by 137

Efficacy of CHK inhibitors as single agents in MYC-driven lymphoma cells

Ferrao, P. T., Bukczynska, E. P., Johnstone, R. W., & McArthur, G. A. (2012) · Oncogene

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 133

Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia

McKenzie, M. D., Ghisi, M., Oxley, E. P., Ngo, S., Cimmino, L., Esnault, C., Liu, R., Salmon, J. M., Bell, C. C., Ahmed, N., et al. (2019) · Cell Stem Cell

Acute Myeloid Leukemia ResearchCancer Cells and Metastasis

Cited by 91

SUGAR-seq enables simultaneous detection of glycans, epitopes, and the transcriptome in single cells

Kearney, C. J., Vervoort, S. J., Ramsbottom, K. M., Todorovski, I., Lelliott, E. J., Zethoven, M., Pijpers, L., Martin, B. P., Semple, T., Martelotto, L., et al. (2021) · Science Advances

Single-cell and spatial transcriptomicsGlycosylation and Glycoproteins Research

Cited by 87

The mTORC1 Inhibitor Everolimus Prevents and Treats Eμ- Myc Lymphoma by Restoring Oncogene-Induced Senescence

Wall, M., Poortinga, G., Stanley, K. L., Lindemann, R. K., Bots, M., Chan, C. J., Bywater, M. J., Kinross, K. M., Astle, M. V., Waldeck, K., et al. (2013) · Cancer Discovery

PI3K/AKT/mTOR signaling in cancerTelomeres, Telomerase, and Senescence

Cited by 64

HDAC3 activity is required for initiation of leukemogenesis in acute promyelocytic leukemia

Mehdipour, P., Santoro, F., Botrugno, O. A., Romanenghi, M., Pagliuca, C., Matthews, G. M., Johnstone, R. W., & Minucci, S. (2017) · Leukemia

Histone Deacetylase Inhibitors ResearchRetinoids in leukemia and cellular processes

Cited by 25

DOCK8 Drives Src-Dependent NK Cell Effector Function

Kearney, C. J., Vervoort, S. J., Ramsbottom, K. M., Freeman, A. J., Michie, J., Peake, J., Casanova, J.-L., Picard, C., Tangye, S. G., Ma, C. S., et al. (2017) · The Journal of Immunology

Immune Cell Function and InteractionImmunodeficiency and Autoimmune Disorders

Cited by 23

A TEXT BOOK OF MIDWIFERY FOR STUDENTS AND PRACTITIONERS

Johnstone, R. W. (1914) · AJN, American Journal of Nursing

Maternal and Perinatal Health InterventionsMedical History and Innovations

Cited by 9