Klingelhutz, Aloysius J.

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells

Kiyono, T., Foster, S. A., Koop, J. I., McDougall, J. K., Galloway, D. A., & Klingelhutz, A. J. (1998) · Nature

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 1,206

Cigarette smoke induces cellular senescence

Nyunoya, T., Monick, M. M., Klingelhutz, A., Yarovinsky, T. O., Cagley, J. R., & Hunninghake, G. W. (2006) · American Journal of Respiratory Cell and Molecular Biology

Telomeres, Telomerase, and SenescenceChronic Obstructive Pulmonary Disease (COPD) Research

Cited by 306

Genetic and Epigenetic Changes in Human Epithelial Cells Immortalized by Telomerase

Farwell, D. G., Shera, K. A., Koop, J. I., Bonnet, G. A., Matthews, C. P., Reuther, G. W., Coltrera, M. D., McDougall, J. K., & Klingelhutz, A. J. (2000) · The American Journal of Pathology

Telomeres, Telomerase, and SenescenceEpigenetics and DNA Methylation

Cited by 196

The role of telomeres in the ageing of human skin: Telomeres and skin ageing

Buckingham, E. M., & Klingelhutz, A. J. (2011) · Experimental Dermatology

Telomeres, Telomerase, and SenescenceSkin Protection and Aging

Cited by 109

Airborne polychlorinated biphenyls (PCBs) reduce telomerase activity and shorten telomere length in immortal human skin keratinocytes (HaCat)

Senthilkumar, P. K., Klingelhutz, A. J., Jacobus, J. A., Lehmler, H., Robertson, L. W., & Ludewig, G. (2011) · Toxicology Letters

Toxic Organic Pollutants ImpactTelomeres, Telomerase, and Senescence

Cited by 45