Hoare, Matthew

Cellular senescence and its effector programs

Salama, R., Sadaie, M., Hoare, M., & Narita, M. (2014) · Genes & Development

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 855

NOTCH1 mediates a switch between two distinct secretomes during senescence

Hoare, M., Ito, Y., Kang, T.-W., Weekes, M. P., Matheson, N. J., Patten, D. A., Shetty, S., Parry, A. J., Menon, S., Salama, R., et al. (2016) · Nature Cell Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 522

Somatic mutations and clonal dynamics in healthy and cirrhotic human liver

Brunner, S. F., Roberts, N. D., Wylie, L. A., Moore, L., Aitken, S. J., Davies, S. E., Sanders, M. A., Ellis, P., Alder, C., Hooks, Y., et al. (2019) · Nature

Cancer Genomics and DiagnosticsLiver physiology and pathology

Cited by 393

Functional skewing of the global CD8 T cell population in chronic hepatitis B virus infection

Das, A., Hoare, M., Davies, N., Lopes, A. R., Dunn, C., Kennedy, P. T. F., Alexander, G., Finney, H., Lawson, A., Plunkett, F. J., et al. (2008) · The Journal of Experimental Medicine

Hepatitis B Virus StudiesT-cell and B-cell Immunology

Cited by 256

Convergent somatic mutations in metabolism genes in chronic liver disease

Ng, S. W. K., Rouhani, F. J., Brunner, S. F., Brzozowska, N., Aitken, S. J., Yang, M., Abascal, F., Moore, L., Nikitopoulou, E., Chappell, L., et al. (2021) · Nature

Cancer Genomics and DiagnosticsLiver Disease Diagnosis and Treatment

Cited by 190

Spatial and Temporal Control of Senescence

Ito, Y., Hoare, M., & Narita, M. (2017) · Trends in Cell Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 178

Multimodal decoding of human liver regeneration

Matchett, K., Wilson-Kanamori, Jr., Portman, Jr., Kapourani, C., Fercoq, F., May, S., Mackey, J., Brice, M., Zajdel, E., Beltran, M., et al. (2023) · Nature

Liver physiology and pathologyDrug-Induced Hepatotoxicity and Protection

Cited by 140

Multimodal decoding of human liver regeneration

Matchett, K. P., Wilson-Kanamori, J. R., Portman, J. R., Kapourani, C. A., Fercoq, F., May, S., Zajdel, E., Beltran, M., Sutherland, E. F., Mackey, J. B. G., et al. (2024) · Nature

Liver physiology and pathologyDrug-Induced Hepatotoxicity and Protection

Cited by 140

Hepatocyte Expression of the Senescence Marker p21 Is Linked to Fibrosis and an Adverse Liver-Related Outcome in Alcohol-Related Liver Disease

Aravinthan, A., Pietrosi, G., Hoare, M., Jupp, J., Marshall, A., Verrill, C., Davies, S., Bateman, A., Sheron, N., Allison, M., et al. (2013) · PLoS ONE

Alcohol Consumption and Health EffectsLiver physiology and pathology

Cited by 117

Transmitting senescence to the cell neighbourhood

Hoare, M., & Narita, M. (2013) · Nature Cell Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 108

NOTCH-mediated non-cell autonomous regulation of chromatin structure during senescence

Parry, A. J., Hoare, M., Bihary, D., Hänsel-Hertsch, R., Smith, S., Tomimatsu, K., Mannion, E., Smith, A., D’Santos, P., Russell, I. A., et al. (2018) · Nature Communications

Telomeres, Telomerase, and SenescenceGenomics and Chromatin Dynamics

Cited by 102

COX2 regulates senescence secretome composition and senescence surveillance through PGE2

Gonçalves, S., Yin, K., Ito, Y., Chan, A., Olan, I., Gough, S., Cassidy, L., Serrao, E., Smith, S., Young, A., et al. (2021) · Cell Reports

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 95

CD4+ T-lymphocyte telomere length is related to fibrosis stage, clinical outcome and treatment response in chronic hepatitis C virus infection

Hoare, M., Gelson, W. T. H., Das, A., Fletcher, J. M., Davies, S. E., Curran, M. D., Vowler, S. L., Maini, M. K., Akbar, A. N., & Alexander, G. J. M. (2010) · Journal of Hepatology

Hepatitis C virus researchTelomeres, Telomerase, and Senescence

Cited by 53

Selection for somatic escape variants in SERPINA1 in the liver of patients with alpha-1 antitrypsin deficiency

Brzozowska, N., Wu, L. Y. D., Khodzhaeva, V., Griffiths, W. J., Duckworth, A., Jung, H., Coorens, T. H. H., Hooks, Y., Chambers, J. E., Campbell, P. J., et al. (2025) · Nature Genetics

Genomics and Rare DiseasesEvolution and Genetic Dynamics

Cited by 11

Senescent Cell–Derived Extracellular Vesicles Inhibit Cancer Recurrence by Coordinating Immune Surveillance

Ziglari, T., Calistri, N. L., Finan, J. M., Derrick, D. S., Nakayasu, E. S., Burnet, M. C., Kyle, J. E., Hoare, M., Heiser, L. M., & Pucci, F. (2025) · Cancer Research

Extracellular vesicles in diseaseTelomeres, Telomerase, and Senescence

Cited by 11

Senescent cell-derived extracellular vesicles inhibit cancer recurrence by coordinating immune surveillance

Ziglari, T., Calistri, N. L., Finan, J. M., Derrick, D., Nakayasu, E. S., Burnet, M. C., Kyle, J. E., Hoare, M., Heiser, L. M., & Pucci, F. (2022) · Cancer Research

Extracellular vesicles in diseaseTelomeres, Telomerase, and Senescence

Cited by 11