Roper, Randall J.

Molecular characterization of the translocation breakpoints in the down syndrome mouse model Ts65Dn

Reinholdt, L. G., Ding, Y., Gilbert, G. T., Czechanski, A., Solzak, J. P., Roper, R. J., Johnson, M. T., Donahue, L. R., Lutz, C., & Davisson, M. T. (2011) · Mammalian Genome

Down syndrome and intellectual disability researchGenomic variations and chromosomal abnormalities

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down syndrome mouse models Ts65Dn, Ts1Cje, and Ms1Cje/Ts65Dn exhibit variable severity of cerebellar phenotypes.

Olson, L. E., Roper, R. J., Baxter, L. L., Carlson, E. J., Epstein, C. J., & Reeves, R. H. (2004) · Developmental Dynamics

Down syndrome and intellectual disability researchGenetics and Neurodevelopmental Disorders

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Evaluation of the therapeutic potential of Epigallocatechin-3-gallate (EGCG) via oral gavage in young adult down syndrome mice

Goodlett, C. R., Stringer, M., LaCombe, J., Patel, R., Wallace, J. M., & Roper, R. J. (2020) · Scientific Reports

Down syndrome and intellectual disability researchTea Polyphenols and Effects

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Sexually dimorphic DYRK1A overexpression on postnatal day 15 in the Ts65Dn mouse model of down syndrome: effects of pharmacological targeting on behavioral phenotypes

Hawley, L. E., Prochaska, F., Stringer, M., Goodlett, C. R., & Roper, R. J. (2022) · Pharmacology Biochemistry and Behavior

Down syndrome and intellectual disability researchGenetics and Neurodevelopmental Disorders

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Sex-specific developmental alterations in DYRK1A expression in the brain of a Down syndrome mouse model

Hawley, L. E., Stringer, M., Deal, A. J., Folz, A., Goodlett, C. R., & Roper, R. J. (2024) · Neurobiology of Disease

Down syndrome and intellectual disability researchGenetics and Neurodevelopmental Disorders

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