Karikari, Thomas K.

APOE ε4 associates with microglial activation independently of Aβ plaques and tau tangles

Ferrari-Souza, J. P., Lussier, F. Z., Leffa, D. T., Therriault, J., Tissot, C., Bellaver, B., Ferreira, P. C. L., Malpetti, M., Wang, Y.-T., Povala, G., et al. (2023) · Science Advances

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 81

Diagnostic value of serum versus plasma phospho-tau for Alzheimer’s disease

Kac, P. R., Gonzalez-Ortiz, F., Simrén, J., Dewit, N., Vanmechelen, E., Zetterberg, H., Blennow, K., Ashton, N. J., & Karikari, T. K. (2022) · Alzheimer's Research & Therapy

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 73

Phosphorylated tau181 in plasma as a potential biomarker for Alzheimer’s disease in adults with Down syndrome

Lleó, A., Zetterberg, H., Pegueroles, J., Karikari, T. K., Carmona-Iragui, M., Ashton, N. J., Montal, V., Barroeta, I., Lantero-Rodríguez, J., Videla, L., et al. (2021) · Nature Communications

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 72

Hippocampal GFAP-positive astrocyte responses to amyloid and tau pathologies

De Bastiani, M. A., Bellaver, B., Brum, W. S., Souza, D. G., Ferreira, P. C. L., Rocha, A. S., Povala, G., Ferrari-Souza, J. P., Benedet, A. L., Ashton, N. J., et al. (2023) · Brain, Behavior, and Immunity

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 57

Association of plasma P-tau181 with memory decline in non-demented adults

Therriault, J., Benedet, A. L., Pascoal, T. A., Lussier, F. Z., Tissot, C., Karikari, T. K., Ashton, N. J., Chamoun, M., Bezgin, G., Mathotaarachchi, S., et al. (2021) · Brain Communications

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 56

APOEε4 potentiates amyloid β effects on longitudinal tau pathology

Ferrari-Souza, J. P., Bellaver, B., Ferreira, P. C. L., Benedet, A. L., Povala, G., Lussier, F. Z., Leffa, D. T., Therriault, J., Tissot, C., Soares, C., et al. (2023) · Nature Aging

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 43

Comparison of CSF and plasma NfL and pNfH for Alzheimer's disease diagnosis: a memory clinic study

Vrillon, A., Ashton, N. J., Karikari, T. K., Götze, K., Cognat, E., Dumurgier, J., Lilamand, M., Zetterberg, H., Blennow, K., & Paquet, C. (2024) · Journal of Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 28

Comorbidities confound Alzheimer’s blood tests

Schindler, S. E., & Karikari, T. K. (2022) · Nature Medicine

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 27

Evaluation of in vivo staging of amyloid deposition in cognitively unimpaired elderly aged 78–94

Michalowska, M. M., Herholz, K., Hinz, R., Amadi, C., McInnes, L., Anton-Rodriguez, J. M., Karikari, T. K., Blennow, K., Zetterberg, H., Ashton, N. J., et al. (2022) · Molecular Psychiatry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 11

Data-driven CSF biomarker profiling: imaging and clinical outcomes in a cohort at risk of Alzheimer’s disease

Argiris, G., Akinci, M., Peña-Gómez, C., Palpatzis, E., Garcia-Prat, M., Shekari, M., Blennow, K., Zetterberg, H., Kollmorgen, G., Quijano-Rubio, C., et al. (2024) · Alzheimer's Research & Therapy

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 6