Lingor, Paul

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

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Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

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Mechanisms of acute axonal degeneration in the optic nerve in vivo

Knöferle, J., Koch, J. C., Ostendorf, T., Michel, U., Planchamp, V., Vutova, P., Tönges, L., Stadelmann, C., Brück, W., Bähr, M., et al. (2010) · Proceedings of the National Academy of Sciences

Nerve injury and regenerationAutophagy in Disease and Therapy

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ROCK inhibition in models of neurodegeneration and its potential for clinical translation

Koch, J. C., Tatenhorst, L., Roser, A.-E., Saal, K.-A., Tönges, L., & Lingor, P. (2018) · Pharmacology & Therapeutics

Protein Kinase Regulation and GTPase SignalingAlzheimer's disease research and treatments

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Inhibition of Rho kinase (ROCK) increases neurite outgrowth on chondroitin sulphate proteoglycan in vitro and axonal regeneration in the adult optic nerve in vivo

Lingor, P., Teusch, N., Schwarz, K., Mueller, R., Mack, H., Bähr, M., & Mueller, B. K. (2007) · Journal of Neurochemistry

Nerve injury and regenerationNeurogenesis and neuroplasticity mechanisms

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ROCK2 is a major regulator of axonal degeneration, neuronal death and axonal regeneration in the CNS

Koch, J. C., Tönges, L., Barski, E., Michel, U., Bähr, M., & Lingor, P. (2014) · Cell Death & Disease

Nerve injury and regenerationAxon Guidance and Neuronal Signaling

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Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson’s disease

Tonges, L., Frank, T., Tatenhorst, L., Saal, K. A., Koch, J. C., Szego, E. M., Bahr, M., Weishaupt, J. H., & Lingor, P. (2012) · Brain

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

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Fasudil attenuates aggregation of α-synuclein in models of Parkinson’s disease

Tatenhorst, L., Eckermann, K., Dambeck, V., Fonseca-Ornelas, L., Walle, H., Lopes da Fonseca, T., Koch, J. C., Becker, S., Tönges, L., Bähr, M., et al. (2016) · Acta Neuropathologica Communications

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

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Rho kinase inhibition modulates microglia activation and improves survival in a model of amyotrophic lateral sclerosis

Tönges, L., Günther, R., Suhr, M., Jansen, J., Balck, A., Saal, K., Barski, E., Nientied, T., Götz, A. A., Koch, J., et al. (2014) · Glia

Amyotrophic Lateral Sclerosis ResearchNeuroinflammation and Neurodegeneration Mechanisms

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Axonal degeneration as a therapeutic target in the CNS

Lingor, P., Koch, J. C., Tönges, L., & Bähr, M. (2012) · Cell and Tissue Research

Nerve injury and regenerationHereditary Neurological Disorders

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Identification of new kinase clusters required for neurite outgrowth and retraction by a loss-of-function RNA interference screen

Loh, S. H. Y., Francescut, L., Lingor, P., Bähr, M., & Nicotera, P. (2008) · Cell Death & Differentiation

Axon Guidance and Neuronal SignalingNerve injury and regeneration

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Modulation of Microglial Activity by Rho-Kinase (ROCK) Inhibition as Therapeutic Strategy in Parkinson’s Disease and Amyotrophic Lateral Sclerosis

Roser, A.-E., Tönges, L., & Lingor, P. (2017) · Frontiers in Aging Neuroscience

Neuroinflammation and Neurodegeneration MechanismsParkinson's Disease Mechanisms and Treatments

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TGF-β 1 enhances neurite outgrowth via regulation of proteasome function and EFABP

Knöferle, J., Ramljak, S., Koch, J. C., Tönges, L., Asif, A. R., Michel, U., Wouters, F. S., Heermann, S., Krieglstein, K., Zerr, I., et al. (2010) · Neurobiology of Disease

Ubiquitin and proteasome pathwaysParkinson's Disease Mechanisms and Treatments

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Rho Kinase Inhibition with Fasudil in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis—Symptomatic Treatment Potential after Disease Onset

Günther, R., Balck, A., Koch, J. C., Nientiedt, T., Sereda, M., Bähr, M., Lingor, P., & Tönges, L. (2017) · Frontiers in Pharmacology

Amyotrophic Lateral Sclerosis ResearchNeurogenetic and Muscular Disorders Research

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The role of autophagy in axonal degeneration of the optic nerve

Koch, J. C., & Lingor, P. (2016) · Experimental Eye Research

Autophagy in Disease and TherapyGlaucoma and retinal disorders

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