Otten, Renee

Predicting multiple conformations via sequence clustering and AlphaFold2

Wayment-Steele, H. K., Ojoawo, A., Otten, R., Apitz, J. M., Pitsawong, W., Hömberger, M., Ovchinnikov, S., Colwell, L., & Kern, D. (2024) · Nature

Protein Structure and DynamicsEnzyme Structure and Function

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Subpolar addition of new cell wall is directed by DivIVA in mycobacteria

Meniche, X., Otten, R., Siegrist, M. S., Baer, C. E., Murphy, K. C., Bertozzi, C. R., & Sassetti, C. M. (2014) · Proceedings of the National Academy of Sciences

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 175

Mechanism of activating mutations and allosteric drug inhibition of the phosphatase SHP2

Pádua, R. A. P., Sun, Y., Marko, I., Pitsawong, W., Stiller, J. B., Otten, R., & Kern, D. (2018) · Nature Communications

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 133

From primordial clocks to circadian oscillators

Pitsawong, W., Pádua, R. A. P., Grant, T., Hoemberger, M., Otten, R., Bradshaw, N., Grigorieff, N., & Kern, D. (2023) · Nature

Circadian rhythm and melatoninLight effects on plants

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The conformational landscape of fold-switcher KaiB is tuned to the circadian rhythm timescale

Wayment-Steele, H. K., Otten, R., Pitsawong, W., Ojoawo, A. M., Glaser, A., Calderone, L. A., & Kern, D. (2024) · Proceedings of the National Academy of Sciences

Protein Structure and DynamicsCircadian rhythm and melatonin

Cited by 19

The conformational landscape of fold-switcher KaiB is tuned to the circadian rhythm timescale

Wayment-Steele, H. K., Otten, R., Pitsawong, W., Ojoawo, A. M., Glaser, A., Calderone, L. A., & Kern, D. (2024) · Proceedings of the National Academy of Sciences

Protein Structure and DynamicsCircadian rhythm and melatonin

Cited by 19