Matsumoto, Shigeyuki

In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras–effector interaction

Shima, F., Yoshikawa, Y., Ye, M., Araki, M., Matsumoto, S., Liao, J., Hu, L., Sugimoto, T., Ijiri, Y., Takeda, A., et al. (2013) · Proceedings of the National Academy of Sciences

Protein Kinase Regulation and GTPase SignalingComputational Drug Discovery Methods

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Chemical genomics language model toward reliable and explainable compound-protein interaction exploration

Koyama, T., Tsumura, H., Okita, R., Yamazaki, K., Hasegawa, A., Imamura, K., Kato, T., Iwata, H., Kojima, R., Inoue, H., et al. (2026) · Journal of Cheminformatics

Computational Drug Discovery MethodsMachine Learning in Bioinformatics

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Data from Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis

Tabata, J., Nakaoku, T., Araki, M., Yoshino, R., Kohsaka, S., Otsuka, A., Ikegami, M., Ui, A., Kanno, S.-I., Miyoshi, K., et al. (2023)

Genomics and Rare DiseasesCancer Genomics and Diagnostics

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